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The map label for this gene is 124027715

Identifier: 124027715

GI number: 124027715

Start: 836735

End: 837808

Strand: Direct

Name: 124027715

Synonym: Hbut_0839

Alternate gene names: NA

Gene position: 836735-837808 (Clockwise)

Preceding gene: 124027708

Following gene: 124027718

Centisome position: 50.19

GC content: 55.12

Gene sequence:

>1074_bases
TTGCCCCGGGTCTGTATGTACTATGACGAGGTCTTCAGACTTCATGAGCCTCCGTATGGTTCACACCCAGAGAGCCCGGA
AAGGCTAGCAATAGCGCTGGAATCGCTGGCCAAGACGGGGCTCTATACGCTGGTGCATATACAGCCAGCGCCTAGGCGTG
GCCTGGAGCGGGATAGGATACTTGAAGTACACGATCCAGCCTATGTCGAGAAGGTTGAGGAGCTTGCTGGACGTGGCGGC
GGCTACATAGACCCAGACACCTACGTTGGGAAGTACACCATACTCGCAGCCCATGCATACACAGCCTCAGTGCTCGATGC
CGTTGACAAGCTAGTTGAGGGAGACTGCAACATAGCTATAGTACTCGGACGTCCACCGGGACACCACGCCGGCCGTCGCG
GCGTCGCAATGGGGGCTCCAACGCTGGGCTTCTGTATATTCAACATCTCGGCACTAGCAGCAAAACACGCTGCCAACCGC
GGCGAGAACGTGCTAGTTGTAGACTTCGACCTGCACCACGGCAATGGGACCCAAGACATACTCTACAGTGATGAAAGGAT
TGTACACCTAGACTTACACCAGGATCCTTCAACAATATATCCTGGCACGGGCTGGCCATGGGAGAACGGGTCTGGGAGGG
CTAGGGGTACAAAGCTAAATGTTATAGTGCCTGTTGACGCTGGAGACGATGTCTATATGATGCTGTTCCAGAGGGGCTTA
GAGCTTGCACAAGCAGTACAGGGAAGTCCGAGCCTAGTCATTGTTGATGCCGGGTTTGACGCCTATGCAGGTGATGGGTT
TGGCATGTTGTACCTCACAACGAACACGTACTACGAGCTGGGCACTACGCTGAGAAGAATGAGGACACGGATACTCGTCG
TGCTTGAGGGTGGCTATAGTATTGGGCTGAGGAGGGCCCTACCAGCATTCATCGCGGGCCTGCTTGGCGAGGCCAACCCG
TATCCAGAGAAGAGGAGCGAGAGCCGCGACGCGGTGTGGAGGACTGCACTGGAGAACTTTGAGCGACTTGAAAAAGCAAT
AGCAGAGGCAAAGAGAAATGCTGGCAGGTTCTAG

Upstream 100 bases:

>100_bases
TCCCCGCAACGCCAGCCACACATTCCCTCTCCGGACAGCTAGCCGCGAGGACGTATAGCCCTGCTTTGGACTATATAGCG
TAGCCTGGGTGCTCCGGGGT

Downstream 100 bases:

>100_bases
CTCTAGAAGGGTGATATGAAGTCCTCCGGCTTTGGCGGCTCTGGCGGCAGACCCTTCCTTTCACGTATCTTCTTCACTAG
GTCCATTAACATGTTGTCTG

Product: histone deacetylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MPRVCMYYDEVFRLHEPPYGSHPESPERLAIALESLAKTGLYTLVHIQPAPRRGLERDRILEVHDPAYVEKVEELAGRGG
GYIDPDTYVGKYTILAAHAYTASVLDAVDKLVEGDCNIAIVLGRPPGHHAGRRGVAMGAPTLGFCIFNISALAAKHAANR
GENVLVVDFDLHHGNGTQDILYSDERIVHLDLHQDPSTIYPGTGWPWENGSGRARGTKLNVIVPVDAGDDVYMMLFQRGL
ELAQAVQGSPSLVIVDAGFDAYAGDGFGMLYLTTNTYYELGTTLRRMRTRILVVLEGGYSIGLRRALPAFIAGLLGEANP
YPEKRSESRDAVWRTALENFERLEKAIAEAKRNAGRF

Sequences:

>Translated_357_residues
MPRVCMYYDEVFRLHEPPYGSHPESPERLAIALESLAKTGLYTLVHIQPAPRRGLERDRILEVHDPAYVEKVEELAGRGG
GYIDPDTYVGKYTILAAHAYTASVLDAVDKLVEGDCNIAIVLGRPPGHHAGRRGVAMGAPTLGFCIFNISALAAKHAANR
GENVLVVDFDLHHGNGTQDILYSDERIVHLDLHQDPSTIYPGTGWPWENGSGRARGTKLNVIVPVDAGDDVYMMLFQRGL
ELAQAVQGSPSLVIVDAGFDAYAGDGFGMLYLTTNTYYELGTTLRRMRTRILVVLEGGYSIGLRRALPAFIAGLLGEANP
YPEKRSESRDAVWRTALENFERLEKAIAEAKRNAGRF
>Mature_356_residues
PRVCMYYDEVFRLHEPPYGSHPESPERLAIALESLAKTGLYTLVHIQPAPRRGLERDRILEVHDPAYVEKVEELAGRGGG
YIDPDTYVGKYTILAAHAYTASVLDAVDKLVEGDCNIAIVLGRPPGHHAGRRGVAMGAPTLGFCIFNISALAAKHAANRG
ENVLVVDFDLHHGNGTQDILYSDERIVHLDLHQDPSTIYPGTGWPWENGSGRARGTKLNVIVPVDAGDDVYMMLFQRGLE
LAQAVQGSPSLVIVDAGFDAYAGDGFGMLYLTTNTYYELGTTLRRMRTRILVVLEGGYSIGLRRALPAFIAGLLGEANPY
PEKRSESRDAVWRTALENFERLEKAIAEAKRNAGRF

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=316, Percent_Identity=31.3291139240506, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI153085395, Length=365, Percent_Identity=29.8630136986301, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI20070354, Length=317, Percent_Identity=32.4921135646688, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI30795202, Length=258, Percent_Identity=32.9457364341085, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI30795204, Length=258, Percent_Identity=32.9457364341085, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI17158039, Length=258, Percent_Identity=32.9457364341085, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI148539870, Length=250, Percent_Identity=31.6, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI169234807, Length=250, Percent_Identity=31.6, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI62750349, Length=358, Percent_Identity=29.8882681564246, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI62750347, Length=358, Percent_Identity=29.8882681564246, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI226529806, Length=317, Percent_Identity=28.7066246056782, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI13128862, Length=312, Percent_Identity=25.6410256410256, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI8923769, Length=318, Percent_Identity=23.2704402515723, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI13128860, Length=316, Percent_Identity=24.3670886075949, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI293336691, Length=288, Percent_Identity=25, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI262073088, Length=174, Percent_Identity=26.4367816091954, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI262073092, Length=237, Percent_Identity=24.4725738396624, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17540334, Length=314, Percent_Identity=33.4394904458599, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17540332, Length=314, Percent_Identity=33.4394904458599, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI193206283, Length=314, Percent_Identity=33.4394904458599, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17537347, Length=334, Percent_Identity=31.437125748503, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI193209491, Length=252, Percent_Identity=30.1587301587302, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25154022, Length=312, Percent_Identity=29.8076923076923, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25154020, Length=312, Percent_Identity=29.4871794871795, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17508561, Length=311, Percent_Identity=25.08038585209, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534739, Length=305, Percent_Identity=22.2950819672131, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17561978, Length=173, Percent_Identity=26.5895953757225, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324307, Length=352, Percent_Identity=29.8295454545455, Blast_Score=136, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6321244, Length=328, Percent_Identity=25.609756097561, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6323999, Length=327, Percent_Identity=23.8532110091743, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6325141, Length=412, Percent_Identity=24.5145631067961, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24642146, Length=343, Percent_Identity=33.2361516034985, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24642144, Length=343, Percent_Identity=33.2361516034985, Blast_Score=141, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24642142, Length=343, Percent_Identity=33.2361516034985, Blast_Score=141, Evalue=7e-34,
Organism=Drosophila melanogaster, GI281360899, Length=343, Percent_Identity=33.2361516034985, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI281360801, Length=236, Percent_Identity=34.3220338983051, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281360799, Length=236, Percent_Identity=34.3220338983051, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24641720, Length=236, Percent_Identity=34.3220338983051, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24644244, Length=318, Percent_Identity=25.1572327044025, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24657891, Length=315, Percent_Identity=26.3492063492064, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 39261; Mature: 39130

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVCMYYDEVFRLHEPPYGSHPESPERLAIALESLAKTGLYTLVHIQPAPRRGLERDRI
CCCEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCE
LEVHDPAYVEKVEELAGRGGGYIDPDTYVGKYTILAAHAYTASVLDAVDKLVEGDCNIAI
EEECCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCEEE
VLGRPPGHHAGRRGVAMGAPTLGFCIFNISALAAKHAANRGENVLVVDFDLHHGNGTQDI
EECCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCE
LYSDERIVHLDLHQDPSTIYPGTGWPWENGSGRARGTKLNVIVPVDAGDDVYMMLFQRGL
EECCCEEEEEEECCCCCEECCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHH
ELAQAVQGSPSLVIVDAGFDAYAGDGFGMLYLTTNTYYELGTTLRRMRTRILVVLEGGYS
HHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCEEEEEEECCCC
IGLRRALPAFIAGLLGEANPYPEKRSESRDAVWRTALENFERLEKAIAEAKRNAGRF
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PRVCMYYDEVFRLHEPPYGSHPESPERLAIALESLAKTGLYTLVHIQPAPRRGLERDRI
CCEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCE
LEVHDPAYVEKVEELAGRGGGYIDPDTYVGKYTILAAHAYTASVLDAVDKLVEGDCNIAI
EEECCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCEEE
VLGRPPGHHAGRRGVAMGAPTLGFCIFNISALAAKHAANRGENVLVVDFDLHHGNGTQDI
EECCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCE
LYSDERIVHLDLHQDPSTIYPGTGWPWENGSGRARGTKLNVIVPVDAGDDVYMMLFQRGL
EECCCEEEEEEECCCCCEECCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHH
ELAQAVQGSPSLVIVDAGFDAYAGDGFGMLYLTTNTYYELGTTLRRMRTRILVVLEGGYS
HHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCEEEEEEECCCC
IGLRRALPAFIAGLLGEANPYPEKRSESRDAVWRTALENFERLEKAIAEAKRNAGRF
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]