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The map label for this gene is moeZ [H]

Identifier: 124027450

GI number: 124027450

Start: 537829

End: 538572

Strand: Direct

Name: moeZ [H]

Synonym: Hbut_0565

Alternate gene names: 124027450

Gene position: 537829-538572 (Clockwise)

Preceding gene: 124027449

Following gene: 124027451

Centisome position: 32.26

GC content: 51.75

Gene sequence:

>744_bases
ATGCCCGGCGAGAAGTTGTCCAGCGAGGAGCTGGCTAGGTATGATAGACAGCTACCACTGTTTGGTATTGGGGGCCAGGC
TAAGCTTAAGAATGTAAGTGTCCTAATCGCTGGCGTTGGTGGGCTTGGATCGTTCGAGGCTATGTATCTTGCTGCGCTTG
GTGTTGGTAGGCTTGTTCTAGTGGACGCTGATTATGTTGACATTACTAATCTTAACAGGCAGGTGCTCTACTGGACTGAG
GATATTGGTAAGCCGAAGCCCTACCCGGCGGCTGAGAAGCTTCGCCGTCTCAACCCGAATGTTGAGGTTGTTGTTGTTAG
GGAGCGTATAACGCCGGAGACGGCGTCCAGGCTTGTGAAGGACGTGGACGTGGTTATTGATGGGCTTGATAACTGGGAGA
CGAGGTTAATTCTCGACGAGGCAGCGTATCGGGCGGGTAAACCATACATCCATGCTGGTGTCTATGGGTTTCAGGGCCAG
GTTGTAGTTGTAGTACCTGGTGAGACGCCCTGTCTGCGGTGTCTACTTCCGCCTTTTCTACGTACGCCAGAGCGCATAAT
AGCAATTAGCCCCGTGGTGGGTATTGTGGCTGGCATAGTAGTGATGGAGCTGGTAAAGCTTGTAACGGGGATTGGTCGCT
CAAATAAGGGAAGAATGATAATAGTTGATACGTATAACATGGAGTTCATGAACGTAGAGCTAAAGCCCCGCAAGGGGTGC
ATGTGTCCCGAGCCTGGGGTGTAA

Upstream 100 bases:

>100_bases
GGTGTTCTGTAGGTTTGATGTACTTGGCAGCCGTCAGGAATATCGGGTTGTGTATGCCCAGAGGCTCTAGTTGGGGCCTG
GCTGGTTTTGGGTGCTGCTT

Downstream 100 bases:

>100_bases
GCTAGGCCGTGGAGTATGAAAAGCTGGTACTTGCAGCGCTTTCCGGCGAAATAGTGTTGAAGTCAGAGCGTACAAGGCCT
AGGTTTGAGCAGAGACTAGT

Product: dinucleotide-utilizing enzyme

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MPGEKLSSEELARYDRQLPLFGIGGQAKLKNVSVLIAGVGGLGSFEAMYLAALGVGRLVLVDADYVDITNLNRQVLYWTE
DIGKPKPYPAAEKLRRLNPNVEVVVVRERITPETASRLVKDVDVVIDGLDNWETRLILDEAAYRAGKPYIHAGVYGFQGQ
VVVVVPGETPCLRCLLPPFLRTPERIIAISPVVGIVAGIVVMELVKLVTGIGRSNKGRMIIVDTYNMEFMNVELKPRKGC
MCPEPGV

Sequences:

>Translated_247_residues
MPGEKLSSEELARYDRQLPLFGIGGQAKLKNVSVLIAGVGGLGSFEAMYLAALGVGRLVLVDADYVDITNLNRQVLYWTE
DIGKPKPYPAAEKLRRLNPNVEVVVVRERITPETASRLVKDVDVVIDGLDNWETRLILDEAAYRAGKPYIHAGVYGFQGQ
VVVVVPGETPCLRCLLPPFLRTPERIIAISPVVGIVAGIVVMELVKLVTGIGRSNKGRMIIVDTYNMEFMNVELKPRKGC
MCPEPGV
>Mature_246_residues
PGEKLSSEELARYDRQLPLFGIGGQAKLKNVSVLIAGVGGLGSFEAMYLAALGVGRLVLVDADYVDITNLNRQVLYWTED
IGKPKPYPAAEKLRRLNPNVEVVVVRERITPETASRLVKDVDVVIDGLDNWETRLILDEAAYRAGKPYIHAGVYGFQGQV
VVVVPGETPCLRCLLPPFLRTPERIIAISPVVGIVAGIVVMELVKLVTGIGRSNKGRMIIVDTYNMEFMNVELKPRKGCM
CPEPGV

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=235, Percent_Identity=40.4255319148936, Blast_Score=151, Evalue=5e-37,
Organism=Homo sapiens, GI23510338, Length=186, Percent_Identity=30.6451612903226, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI23510340, Length=186, Percent_Identity=30.6451612903226, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI38045948, Length=181, Percent_Identity=33.1491712707182, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI38045944, Length=181, Percent_Identity=33.1491712707182, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI38045942, Length=181, Percent_Identity=33.1491712707182, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI13376212, Length=239, Percent_Identity=30.1255230125523, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4885649, Length=150, Percent_Identity=30.6666666666667, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI150417996, Length=164, Percent_Identity=29.8780487804878, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI38327032, Length=210, Percent_Identity=30, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI225543285, Length=157, Percent_Identity=29.2993630573248, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4885585, Length=154, Percent_Identity=29.2207792207792, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI225543288, Length=154, Percent_Identity=29.2207792207792, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787048, Length=243, Percent_Identity=32.9218106995885, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87082356, Length=242, Percent_Identity=37.1900826446281, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1789177, Length=147, Percent_Identity=29.9319727891156, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17540406, Length=240, Percent_Identity=30, Blast_Score=127, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI193203301, Length=158, Percent_Identity=29.1139240506329, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71984476, Length=179, Percent_Identity=30.7262569832402, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI86565433, Length=187, Percent_Identity=28.3422459893048, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI86565431, Length=187, Percent_Identity=28.3422459893048, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508819, Length=238, Percent_Identity=28.9915966386555, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321903, Length=215, Percent_Identity=33.953488372093, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322639, Length=174, Percent_Identity=31.0344827586207, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6325323, Length=153, Percent_Identity=35.2941176470588, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320598, Length=157, Percent_Identity=28.6624203821656, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6325438, Length=141, Percent_Identity=30.4964539007092, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582879, Length=242, Percent_Identity=35.9504132231405, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28573937, Length=186, Percent_Identity=32.258064516129, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24660640, Length=150, Percent_Identity=31.3333333333333, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI20129973, Length=200, Percent_Identity=31, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641311, Length=222, Percent_Identity=27.9279279279279, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 27086; Mature: 26955

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGEKLSSEELARYDRQLPLFGIGGQAKLKNVSVLIAGVGGLGSFEAMYLAALGVGRLVL
CCCCCCCHHHHHHHHCCCCEEECCCCCEECEEEEEEEECCCCCHHHHHHHHHHCCCEEEE
VDADYVDITNLNRQVLYWTEDIGKPKPYPAAEKLRRLNPNVEVVVVRERITPETASRLVK
EECCEEEECCCCCEEEEEEHHCCCCCCCCHHHHHHHCCCCEEEEEEECCCCHHHHHHHHH
DVDVVIDGLDNWETRLILDEAAYRAGKPYIHAGVYGFQGQVVVVVPGETPCLRCLLPPFL
HHHHEEECCCCCCEEEEEEHHHHHCCCCEEEEEEECCCCEEEEEECCCCCHHHHHCCHHH
RTPERIIAISPVVGIVAGIVVMELVKLVTGIGRSNKGRMIIVDTYNMEFMNVELKPRKGC
CCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEEECCCCCC
MCPEPGV
CCCCCCC
>Mature Secondary Structure 
PGEKLSSEELARYDRQLPLFGIGGQAKLKNVSVLIAGVGGLGSFEAMYLAALGVGRLVL
CCCCCCHHHHHHHHCCCCEEECCCCCEECEEEEEEEECCCCCHHHHHHHHHHCCCEEEE
VDADYVDITNLNRQVLYWTEDIGKPKPYPAAEKLRRLNPNVEVVVVRERITPETASRLVK
EECCEEEECCCCCEEEEEEHHCCCCCCCCHHHHHHHCCCCEEEEEEECCCCHHHHHHHHH
DVDVVIDGLDNWETRLILDEAAYRAGKPYIHAGVYGFQGQVVVVVPGETPCLRCLLPPFL
HHHHEEECCCCCCEEEEEEHHHHHCCCCEEEEEEECCCCEEEEEECCCCCHHHHHCCHHH
RTPERIIAISPVVGIVAGIVVMELVKLVTGIGRSNKGRMIIVDTYNMEFMNVELKPRKGC
CCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEEECCCCCC
MCPEPGV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]