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The map label for this gene is 124027394

Identifier: 124027394

GI number: 124027394

Start: 489449

End: 490450

Strand: Direct

Name: 124027394

Synonym: Hbut_0507

Alternate gene names: NA

Gene position: 489449-490450 (Clockwise)

Preceding gene: 124027393

Following gene: 124027395

Centisome position: 29.36

GC content: 52.1

Gene sequence:

>1002_bases
GTGGAGGAGATACTAGTCCGAGCCTCTATAGGCACCCTTGCAGCTCTAGGTCTTGCAGGGATACGAGTAGCTGCAAAACC
TACAACCGCCTACTTACTCCAGTATAGTCCCTACGGCTGCCTCGCCGGGTGCAAGTTCTGTACACAGTCTCTACGCTCGC
CAGCAAGTAAGGATATGCTTTCAAGAGTAAAATGGCCAGTAGTTAGGCTCACTGAGCTACTGGCAGCATGGCGGAAGGCA
GGTAGGCCATTTACGAGAATCTGTATTCAGACCGTTGTAAAGCCATGGTTTGGTTGCGAAGCTGCAAGAATTCTCGAGGC
CATACGAACCATAGACCAAGAGACCCCTGCCTCTATAGCCTCAACACCTGTATCTACAAGGCTCCTATTGTACTGGAAGA
GTCTAGGTGTGGACTATCTCGGCGTAGGCCTTGATGCTGTTACTCCAACGGTATTTAGGCGTGCTGGCAAACCATTCACA
TGGACAAGCTACATGGACTTTATTGAGAGAGGTATAGCTGTCTACGGTCGCGGTCACGTATATGTACACTTGATAGTTGG
GCTCGGCGAAAAGCCTACAGAGATTATAAGGCTCATGGAGAAGCTCTACGCCATGGGTGCTCGTGTAGCGCTATTCAACT
ACACGGCTGTAACAAGCTGGAAGACAAGCAGCGTAAGAATCGAGGACTACCGGCTGCTCCAGCTAGCCCGTGAAATCCTT
GAAGAAGGCCTAGATCCCTGGGACTACATCGAGGAGAGGAATGGCAGCCTCGTGCTCCGCGAGTGCCCCCCAGTAAACCT
TGTAAAAGCTGTATTGACGAGCGGTTGTCCAGGCTGCAATAGACCATTCTACAACGAGAGTCCCCGCGGCCCGATCTACA
ACTATCCAAGCCCAGCGCTAGCTGTAAGGGATAGGGAGGCACTGAAGCACCAACTGCTAGGCAGAGCTAGAGGGCTGGAG
AGGTGTATCGAAGGGTGGGTATCGCAGTCTTCAGGCTCATAG

Upstream 100 bases:

>100_bases
TGGAGATTGTTGCATGTGAAAAGCTAGAGCCTATACTCGAGAATAACCCGGATAAAACAGTGATAGTGACAATTGCTTGC
AAGCGGGGCGATGCGCTACG

Downstream 100 bases:

>100_bases
CAAGGTTCTCAGAGGTAAGCCTCACCGGGCCCCACTGTGCCCTCAACTGCCACCACTGTAGAGGCAAGTACTTGAGGCAC
ATGCTTAAACCGCTACCCGG

Product: biotin synthase-related enzyme

Products: biotin

Alternate protein names: Radical SAM Domain-Containing Protein; Biotin Synthase Related Protein; Biotin Synthase; Biotin Synthase-Related Protein; Radical SAM Superfamily Protein; Biotin Synthase-Related; Radical SAM Family Protein

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MEEILVRASIGTLAALGLAGIRVAAKPTTAYLLQYSPYGCLAGCKFCTQSLRSPASKDMLSRVKWPVVRLTELLAAWRKA
GRPFTRICIQTVVKPWFGCEAARILEAIRTIDQETPASIASTPVSTRLLLYWKSLGVDYLGVGLDAVTPTVFRRAGKPFT
WTSYMDFIERGIAVYGRGHVYVHLIVGLGEKPTEIIRLMEKLYAMGARVALFNYTAVTSWKTSSVRIEDYRLLQLAREIL
EEGLDPWDYIEERNGSLVLRECPPVNLVKAVLTSGCPGCNRPFYNESPRGPIYNYPSPALAVRDREALKHQLLGRARGLE
RCIEGWVSQSSGS

Sequences:

>Translated_333_residues
MEEILVRASIGTLAALGLAGIRVAAKPTTAYLLQYSPYGCLAGCKFCTQSLRSPASKDMLSRVKWPVVRLTELLAAWRKA
GRPFTRICIQTVVKPWFGCEAARILEAIRTIDQETPASIASTPVSTRLLLYWKSLGVDYLGVGLDAVTPTVFRRAGKPFT
WTSYMDFIERGIAVYGRGHVYVHLIVGLGEKPTEIIRLMEKLYAMGARVALFNYTAVTSWKTSSVRIEDYRLLQLAREIL
EEGLDPWDYIEERNGSLVLRECPPVNLVKAVLTSGCPGCNRPFYNESPRGPIYNYPSPALAVRDREALKHQLLGRARGLE
RCIEGWVSQSSGS
>Mature_333_residues
MEEILVRASIGTLAALGLAGIRVAAKPTTAYLLQYSPYGCLAGCKFCTQSLRSPASKDMLSRVKWPVVRLTELLAAWRKA
GRPFTRICIQTVVKPWFGCEAARILEAIRTIDQETPASIASTPVSTRLLLYWKSLGVDYLGVGLDAVTPTVFRRAGKPFT
WTSYMDFIERGIAVYGRGHVYVHLIVGLGEKPTEIIRLMEKLYAMGARVALFNYTAVTSWKTSSVRIEDYRLLQLAREIL
EEGLDPWDYIEERNGSLVLRECPPVNLVKAVLTSGCPGCNRPFYNESPRGPIYNYPSPALAVRDREALKHQLLGRARGLE
RCIEGWVSQSSGS

Specific function: Unknown

COG id: COG2516

COG function: function code R; Biotin synthase-related enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.8.1.6

Molecular weight: Translated: 37078; Mature: 37078

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEILVRASIGTLAALGLAGIRVAAKPTTAYLLQYSPYGCLAGCKFCTQSLRSPASKDML
CCCCEEEHHHHHHHHHHHHHHEEECCCCEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHH
SRVKWPVVRLTELLAAWRKAGRPFTRICIQTVVKPWFGCEAARILEAIRTIDQETPASIA
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHH
STPVSTRLLLYWKSLGVDYLGVGLDAVTPTVFRRAGKPFTWTSYMDFIERGIAVYGRGHV
CCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEECCCEE
YVHLIVGLGEKPTEIIRLMEKLYAMGARVALFNYTAVTSWKTSSVRIEDYRLLQLAREIL
EEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEHEEECCCCCCEEHHHHHHHHHHHHHH
EEGLDPWDYIEERNGSLVLRECPPVNLVKAVLTSGCPGCNRPFYNESPRGPIYNYPSPAL
HHCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
AVRDREALKHQLLGRARGLERCIEGWVSQSSGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEEILVRASIGTLAALGLAGIRVAAKPTTAYLLQYSPYGCLAGCKFCTQSLRSPASKDML
CCCCEEEHHHHHHHHHHHHHHEEECCCCEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHH
SRVKWPVVRLTELLAAWRKAGRPFTRICIQTVVKPWFGCEAARILEAIRTIDQETPASIA
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHH
STPVSTRLLLYWKSLGVDYLGVGLDAVTPTVFRRAGKPFTWTSYMDFIERGIAVYGRGHV
CCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEECCCEE
YVHLIVGLGEKPTEIIRLMEKLYAMGARVALFNYTAVTSWKTSSVRIEDYRLLQLAREIL
EEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEHEEECCCCCCEEHHHHHHHHHHHHHH
EEGLDPWDYIEERNGSLVLRECPPVNLVKAVLTSGCPGCNRPFYNESPRGPIYNYPSPAL
HHCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
AVRDREALKHQLLGRARGLERCIEGWVSQSSGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dethiobiotin; sulfur

Specific reaction: dethiobiotin + sulfur = biotin

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA