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The map label for this gene is yggV [C]

Identifier: 124027323

GI number: 124027323

Start: 420364

End: 420936

Strand: Reverse

Name: yggV [C]

Synonym: Hbut_0432

Alternate gene names: 124027323

Gene position: 420936-420364 (Counterclockwise)

Preceding gene: 124027324

Following gene: 124027322

Centisome position: 25.25

GC content: 52.18

Gene sequence:

>573_bases
ATGGAGGCAAGAGTAATCCTCATCGCGACCACAAACAAGCACAAGATTGAAGAGATAAACGAGGTACTCCAGAGCTGCGG
CTACCGAGTAGAGCCAGCAGCGGCATCAAAACTAGAAGTACAGTCCAATAGGCTCGAAGATGTTGCCGCCTATGCAGCCA
TTCAAGCATACTTGGCTTTACAGCGTCCAGTAATAGTAGAAGATGCGGGACTCTTTGTGGAAGCTCTCGGCGGGTTCCCC
GGACCCTACTCATCCTACGTCTTCAAAACCATAGGTATTAGGGGGCTGCTTAAACTCCTGGAGGATGTTGAAAACCGAAG
AGCATACTTCAAATCCGTCATAGCCCTAGCTCATAGTGGAGGCGTGGAAGTATTCACCGGTACAGTCCACGGAGTAATCG
CTGAGAAGCCGCGCGGAGATAGGGGCTTCGGATACGATCCAGTATTCATACCCGAAGGCTCGTCTAAGACCTTTGCCGAG
ATGGAAACCCAGGAGAAGAACAAGTTCTCGCACCGCGGAAAGGCAGCCAGAGAGCTGTGCAGATGGCTACGGCAATACGG
GCCGCCACGATAG

Upstream 100 bases:

>100_bases
GCTACCGCAGTGTGCGGGGTGCCGATAAGACGGAAAGGATTATGGAGCTTGTGAGGGAGATAAGGCTCATGGGCCGCTAT
AGGGCGGAGAGGAGGACAGC

Downstream 100 bases:

>100_bases
CAGTGCTGCGAGCGATAGCACTACTTATAGCCCCCTACCGGGCATAGCCGCGCAACGAGACCTGGAGCCCCCGGGAGTAG
GGGGCTCCCCAGCCCCTAGA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MEARVILIATTNKHKIEEINEVLQSCGYRVEPAAASKLEVQSNRLEDVAAYAAIQAYLALQRPVIVEDAGLFVEALGGFP
GPYSSYVFKTIGIRGLLKLLEDVENRRAYFKSVIALAHSGGVEVFTGTVHGVIAEKPRGDRGFGYDPVFIPEGSSKTFAE
METQEKNKFSHRGKAARELCRWLRQYGPPR

Sequences:

>Translated_190_residues
MEARVILIATTNKHKIEEINEVLQSCGYRVEPAAASKLEVQSNRLEDVAAYAAIQAYLALQRPVIVEDAGLFVEALGGFP
GPYSSYVFKTIGIRGLLKLLEDVENRRAYFKSVIALAHSGGVEVFTGTVHGVIAEKPRGDRGFGYDPVFIPEGSSKTFAE
METQEKNKFSHRGKAARELCRWLRQYGPPR
>Mature_190_residues
MEARVILIATTNKHKIEEINEVLQSCGYRVEPAAASKLEVQSNRLEDVAAYAAIQAYLALQRPVIVEDAGLFVEALGGFP
GPYSSYVFKTIGIRGLLKLLEDVENRRAYFKSVIALAHSGGVEVFTGTVHGVIAEKPRGDRGFGYDPVFIPEGSSKTFAE
METQEKNKFSHRGKAARELCRWLRQYGPPR

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=179, Percent_Identity=35.195530726257, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI31657144, Length=137, Percent_Identity=39.4160583941606, Blast_Score=95, Evalue=3e-20,
Organism=Escherichia coli, GI1789324, Length=195, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17556833, Length=187, Percent_Identity=34.7593582887701, Blast_Score=106, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6322529, Length=195, Percent_Identity=32.3076923076923, Blast_Score=89, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19920712, Length=177, Percent_Identity=35.0282485875706, Blast_Score=103, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_HYPBU (A2BJY7)

Other databases:

- EMBL:   CP000493
- RefSeq:   YP_001012643.1
- ProteinModelPortal:   A2BJY7
- SMR:   A2BJY7
- STRING:   A2BJY7
- GeneID:   4782980
- GenomeReviews:   CP000493_GR
- KEGG:   hbu:Hbut_0432
- eggNOG:   arNOG10472
- HOGENOM:   HBG697237
- OMA:   FAYDSIF
- PhylomeDB:   A2BJY7
- ProtClustDB:   PRK14821
- BioCyc:   HBUT415426:HBUT_0432-MONOMER
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 21059; Mature: 21059

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEARVILIATTNKHKIEEINEVLQSCGYRVEPAAASKLEVQSNRLEDVAAYAAIQAYLAL
CCCEEEEEEECCCHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QRPVIVEDAGLFVEALGGFPGPYSSYVFKTIGIRGLLKLLEDVENRRAYFKSVIALAHSG
CCCEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVEVFTGTVHGVIAEKPRGDRGFGYDPVFIPEGSSKTFAEMETQEKNKFSHRGKAARELC
CCEEEECHHHEEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
RWLRQYGPPR
HHHHHHCCCC
>Mature Secondary Structure
MEARVILIATTNKHKIEEINEVLQSCGYRVEPAAASKLEVQSNRLEDVAAYAAIQAYLAL
CCCEEEEEEECCCHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QRPVIVEDAGLFVEALGGFPGPYSSYVFKTIGIRGLLKLLEDVENRRAYFKSVIALAHSG
CCCEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVEVFTGTVHGVIAEKPRGDRGFGYDPVFIPEGSSKTFAEMETQEKNKFSHRGKAARELC
CCEEEECHHHEEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
RWLRQYGPPR
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA