Click here to switch to the map view.

The map label for this gene is ypnP [H]

Identifier: 124027179

GI number: 124027179

Start: 267350

End: 268774

Strand: Direct

Name: ypnP [H]

Synonym: Hbut_0282

Alternate gene names: 124027179

Gene position: 267350-268774 (Clockwise)

Preceding gene: 124027178

Following gene: 124027183

Centisome position: 16.04

GC content: 57.96

Gene sequence:

>1425_bases
TTGGCTGACGCTGGTGAGCGGCTGGGGAGGCTGCGGGAGAGGGTTCTCAGCGAGGAGAATATTGTCCGGCTCCTCGTGTG
GCTTGCCGTGCCGTTGATGGCTTCTAGTAGTGTTAGGATACTCTACGAAGCTGTGGACGCTTTCTGGCTGTCGAGGCTCG
GCGAGGCCGCCCTCGGCACACCAATAGTCTCGTGGCCCTATCCTGACATAGTGTTTGCTGTAGCGTTTGGCCTCTCGGGC
AGCGTATCAGCCATAGCAGGCCAGTACATCGGGGCCGGCCTCTACGACCGAGCTTCGCGCAGCGCCGGCACCGTCCTAGG
CCTCATAATGATTGTCGCCGTGCCCGGCTCCATAGCTATAGCTGCTACTGCGCCGCTCTACCTCGATGCTATAGGGGTGC
CCGAGACCGTTAAGCCCCTCGCCGAAGTGTACCTGGCCATCATAGCGCTCGGCACACCGTTCTCGGCGCTATTCCTCTTC
TTCAACATGCTGCTGGGAGCAGCCGGCGACACGAGGACACCGGTTAAGGTGTCTATAGCAGCTACAGCGATAAACGCTGT
TCTAGACCCCATACTGATATTCGTGGCTGACCTCGGCGTCCTCGGAGCTGCTCTTGCCACCTTTATAGCCTCCCTGTTCT
CCGCCAGCTATGCCGCCTATAGCCTAGCCACGGGGAGGCACGGGTTCAGGCTGGGTATTCGGGACCTCATACCCGACCGC
AGCCTGTTACCGCTTGTCGCCAAGGTCTCGGCGCCGCTGGTGGTGCAGCGTCTAGGCATGACATTGGGCTTTATGGTTAT
GGCTGGCATCGTGGCTGGCTTGGGCGAGGTAGTGCTGGCAGCATACCAGGTTGGCCACGTGGCGCTCAGCATTGACTCGA
TAATATCGATGCCTCTAGCCCGCTCGGTAGGCATAGTCGTAGCCCAATCCCTCGGCGCAGGCCAGACCTGGAGGGCGCGC
AAAGCCGTGAAAACCGGGCTACTACTCCTAGCAGGCTTCGTCGGAGCATACATAGCAGCCATAGTCTACTTCGCCGAAGA
GTTTGCTAGGATATTCACTAGCAACCCGGAAACAGTAAAGGTTATAGTGGACATGCTCCACGTCTTCGGGCCAAGCATAC
TATCCTTCAACTTACTCACATTAGCAAATGTCGTAGCGAGGAGCAGCGGCCACACGTTCTTCATATCAGCCCTAGGCATA
GCTAGGCTGTGGTTCCTCCGGATACCCCTCTCATGGCTTCTAGCCTACCAGCTAGGCCTAGGCGAGAAGGGACTATGGGC
AGGCATGGCTATAAGCAACCACGTAGCCGGTGGAACAGCCCTAGCATGGCTAGCCTACGGCAACTGGGCCAAACCAGTAA
TAACGCAGGAGCAAAGAGAGCATAAACCCGGACACATGAAGACACAGTCACAACAGCAGGGCTAG

Upstream 100 bases:

>100_bases
GTGGCGAGGTGCCGCGGCTAGGGAGGACCCAGCCCCTTCGGAGGCTGCCTACTAGTTTTTGAAGAACGGTTTCCTCCTCT
CGCCCTGCCGGCTGTGAGCC

Downstream 100 bases:

>100_bases
ACAAGTACGAGCCTTGAGAACCCGAAACCAGCAGAGGAGCAAGTCCCAAGCTATCCCGAGATCAGGAAGGGGACGGGAAG
CTACTCTCCCTGCGGGCCTG

Product: Na+-driven multidrug efflux pump, NorM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MADAGERLGRLRERVLSEENIVRLLVWLAVPLMASSSVRILYEAVDAFWLSRLGEAALGTPIVSWPYPDIVFAVAFGLSG
SVSAIAGQYIGAGLYDRASRSAGTVLGLIMIVAVPGSIAIAATAPLYLDAIGVPETVKPLAEVYLAIIALGTPFSALFLF
FNMLLGAAGDTRTPVKVSIAATAINAVLDPILIFVADLGVLGAALATFIASLFSASYAAYSLATGRHGFRLGIRDLIPDR
SLLPLVAKVSAPLVVQRLGMTLGFMVMAGIVAGLGEVVLAAYQVGHVALSIDSIISMPLARSVGIVVAQSLGAGQTWRAR
KAVKTGLLLLAGFVGAYIAAIVYFAEEFARIFTSNPETVKVIVDMLHVFGPSILSFNLLTLANVVARSSGHTFFISALGI
ARLWFLRIPLSWLLAYQLGLGEKGLWAGMAISNHVAGGTALAWLAYGNWAKPVITQEQREHKPGHMKTQSQQQG

Sequences:

>Translated_474_residues
MADAGERLGRLRERVLSEENIVRLLVWLAVPLMASSSVRILYEAVDAFWLSRLGEAALGTPIVSWPYPDIVFAVAFGLSG
SVSAIAGQYIGAGLYDRASRSAGTVLGLIMIVAVPGSIAIAATAPLYLDAIGVPETVKPLAEVYLAIIALGTPFSALFLF
FNMLLGAAGDTRTPVKVSIAATAINAVLDPILIFVADLGVLGAALATFIASLFSASYAAYSLATGRHGFRLGIRDLIPDR
SLLPLVAKVSAPLVVQRLGMTLGFMVMAGIVAGLGEVVLAAYQVGHVALSIDSIISMPLARSVGIVVAQSLGAGQTWRAR
KAVKTGLLLLAGFVGAYIAAIVYFAEEFARIFTSNPETVKVIVDMLHVFGPSILSFNLLTLANVVARSSGHTFFISALGI
ARLWFLRIPLSWLLAYQLGLGEKGLWAGMAISNHVAGGTALAWLAYGNWAKPVITQEQREHKPGHMKTQSQQQG
>Mature_473_residues
ADAGERLGRLRERVLSEENIVRLLVWLAVPLMASSSVRILYEAVDAFWLSRLGEAALGTPIVSWPYPDIVFAVAFGLSGS
VSAIAGQYIGAGLYDRASRSAGTVLGLIMIVAVPGSIAIAATAPLYLDAIGVPETVKPLAEVYLAIIALGTPFSALFLFF
NMLLGAAGDTRTPVKVSIAATAINAVLDPILIFVADLGVLGAALATFIASLFSASYAAYSLATGRHGFRLGIRDLIPDRS
LLPLVAKVSAPLVVQRLGMTLGFMVMAGIVAGLGEVVLAAYQVGHVALSIDSIISMPLARSVGIVVAQSLGAGQTWRARK
AVKTGLLLLAGFVGAYIAAIVYFAEEFARIFTSNPETVKVIVDMLHVFGPSILSFNLLTLANVVARSSGHTFFISALGIA
RLWFLRIPLSWLLAYQLGLGEKGLWAGMAISNHVAGGTALAWLAYGNWAKPVITQEQREHKPGHMKTQSQQQG

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=473, Percent_Identity=23.2558139534884, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 50084; Mature: 49952

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAGERLGRLRERVLSEENIVRLLVWLAVPLMASSSVRILYEAVDAFWLSRLGEAALGT
CCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHCC
PIVSWPYPDIVFAVAFGLSGSVSAIAGQYIGAGLYDRASRSAGTVLGLIMIVAVPGSIAI
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHCCCCEEE
AATAPLYLDAIGVPETVKPLAEVYLAIIALGTPFSALFLFFNMLLGAAGDTRTPVKVSIA
EECCCHHEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEHH
ATAINAVLDPILIFVADLGVLGAALATFIASLFSASYAAYSLATGRHGFRLGIRDLIPDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHCCCC
SLLPLVAKVSAPLVVQRLGMTLGFMVMAGIVAGLGEVVLAAYQVGHVALSIDSIISMPLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHH
RSVGIVVAQSLGAGQTWRARKAVKTGLLLLAGFVGAYIAAIVYFAEEFARIFTSNPETVK
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VIVDMLHVFGPSILSFNLLTLANVVARSSGHTFFISALGIARLWFLRIPLSWLLAYQLGL
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
GEKGLWAGMAISNHVAGGTALAWLAYGNWAKPVITQEQREHKPGHMKTQSQQQG
CCCCCEECHHHHCCCCCCHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADAGERLGRLRERVLSEENIVRLLVWLAVPLMASSSVRILYEAVDAFWLSRLGEAALGT
CCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHCC
PIVSWPYPDIVFAVAFGLSGSVSAIAGQYIGAGLYDRASRSAGTVLGLIMIVAVPGSIAI
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHCCCCEEE
AATAPLYLDAIGVPETVKPLAEVYLAIIALGTPFSALFLFFNMLLGAAGDTRTPVKVSIA
EECCCHHEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEHH
ATAINAVLDPILIFVADLGVLGAALATFIASLFSASYAAYSLATGRHGFRLGIRDLIPDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHCCCC
SLLPLVAKVSAPLVVQRLGMTLGFMVMAGIVAGLGEVVLAAYQVGHVALSIDSIISMPLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHH
RSVGIVVAQSLGAGQTWRARKAVKTGLLLLAGFVGAYIAAIVYFAEEFARIFTSNPETVK
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VIVDMLHVFGPSILSFNLLTLANVVARSSGHTFFISALGIARLWFLRIPLSWLLAYQLGL
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
GEKGLWAGMAISNHVAGGTALAWLAYGNWAKPVITQEQREHKPGHMKTQSQQQG
CCCCCEECHHHHCCCCCCHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]