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The map label for this gene is fhuC [H]

Identifier: 124027071

GI number: 124027071

Start: 157233

End: 157910

Strand: Direct

Name: fhuC [H]

Synonym: Hbut_0174

Alternate gene names: 124027071

Gene position: 157233-157910 (Clockwise)

Preceding gene: 124027070

Following gene: 124027072

Centisome position: 9.43

GC content: 55.6

Gene sequence:

>678_bases
TTGGCCCAAACGGTGCTGGCAAGACAACACTCCTCAAGGACACTAGCCGGGATAATTAAGCCAACCCGGGGAGTGGTAAA
ACTCGATGGCAAGCCGGTACATGCGATGAACCCTCGTACCCGGGCAAGACTAATCGCCTACACTCCGGTCGCCCTCGAGG
CGCCAGGCCTAGGCCAAACAGTGGCAGAATACGTGGCTGCGAGCCTCTACCCCTACGGTCACAGCCTCAAAATAGGCCTA
ACCAGCTACGACCTCCAGGAAGCAATAACCCATCTAGGAAAGCTAGAAGCTGAACACCTAGCACAACGGAGACTAGCAAC
CCTAAGCAGTGGCGAGCAAAAACGCAGCATTATAGCCCACGGCCTCGCCAGGAGGCCCATAGTGCTACTCGCCGACGAGC
CAACAAGCCTACTAGACATGAGGGCCCGGCTACTAGCCTACAGAGTGCTCCGCCTAGAAGCAGAGAAGGGCCGGATAGTC
GTGGCATCAACCCACGACATGCTTCTTGCGGCACTCTATGCAGACCACGTAGTAGTCATAGATAAGGGCGTGGTCGTAGC
GCAGGGCACAGCGGGAAAAGTACTATCCAGCGAGCTTCTCGAGGCAGTCTTCTCGGTTAAGATAGCAGTAGCAGAAGTGG
ATGGAAGAACAGTCCCCATACCACTTGAGCCACTTTAA

Upstream 100 bases:

>100_bases
CACGTCCTAGAGGCTGAGAACGTCACAGTAGAGTTCAACGGTAGAATAGTACTCCGGGACATAAACCTGAAGCTCGAGTC
AGGTAAGCTCACGGTAATCC

Downstream 100 bases:

>100_bases
GCAGTAAGAAACAGGTATTGTAGAAAAGCAAAGGTTTTTAGAAACCTTCTTACCCGTGATTTTCCGAAAGACATGGTAAT
ATATACAAGCAGTCGAAACG

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MAQTVLARQHSSRTLAGIIKPTRGVVKLDGKPVHAMNPRTRARLIAYTPVALEAPGLGQTVAEYVAASLYPYGHSLKIGL
TSYDLQEAITHLGKLEAEHLAQRRLATLSSGEQKRSIIAHGLARRPIVLLADEPTSLLDMRARLLAYRVLRLEAEKGRIV
VASTHDMLLAALYADHVVVIDKGVVVAQGTAGKVLSSELLEAVFSVKIAVAEVDGRTVPIPLEPL

Sequences:

>Translated_225_residues
MAQTVLARQHSSRTLAGIIKPTRGVVKLDGKPVHAMNPRTRARLIAYTPVALEAPGLGQTVAEYVAASLYPYGHSLKIGL
TSYDLQEAITHLGKLEAEHLAQRRLATLSSGEQKRSIIAHGLARRPIVLLADEPTSLLDMRARLLAYRVLRLEAEKGRIV
VASTHDMLLAALYADHVVVIDKGVVVAQGTAGKVLSSELLEAVFSVKIAVAEVDGRTVPIPLEPL
>Mature_224_residues
AQTVLARQHSSRTLAGIIKPTRGVVKLDGKPVHAMNPRTRARLIAYTPVALEAPGLGQTVAEYVAASLYPYGHSLKIGLT
SYDLQEAITHLGKLEAEHLAQRRLATLSSGEQKRSIIAHGLARRPIVLLADEPTSLLDMRARLLAYRVLRLEAEKGRIVV
ASTHDMLLAALYADHVVVIDKGVVVAQGTAGKVLSSELLEAVFSVKIAVAEVDGRTVPIPLEPL

Specific function: Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system [H]

COG id: COG1120

COG function: function code PH; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1786345, Length=193, Percent_Identity=35.2331606217617, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI1790739, Length=206, Percent_Identity=33.495145631068, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1786803, Length=214, Percent_Identity=31.7757009345794, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788225, Length=84, Percent_Identity=42.8571428571429, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788644, Length=122, Percent_Identity=33.6065573770492, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787029, Length=111, Percent_Identity=36.9369369369369, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.34 [H]

Molecular weight: Translated: 24239; Mature: 24108

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTVLARQHSSRTLAGIIKPTRGVVKLDGKPVHAMNPRTRARLIAYTPVALEAPGLGQT
CCCCHHHHHCCCCCEEEEECCCCCEEEECCCCEECCCCCCCEEEEEECCEEEECCCCHHH
VAEYVAASLYPYGHSLKIGLTSYDLQEAITHLGKLEAEHLAQRRLATLSSGEQKRSIIAH
HHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHH
GLARRPIVLLADEPTSLLDMRARLLAYRVLRLEAEKGRIVVASTHDMLLAALYADHVVVI
HHCCCCEEEEECCCHHHHHHHHHHHHHHHHHEECCCCEEEEEEHHHHHHHHHHHCEEEEE
DKGVVVAQGTAGKVLSSELLEAVFSVKIAVAEVDGRTVPIPLEPL
ECCEEEECCCCCHHHHHHHHHHHHHHEEEEEECCCCEECCCCCCC
>Mature Secondary Structure 
AQTVLARQHSSRTLAGIIKPTRGVVKLDGKPVHAMNPRTRARLIAYTPVALEAPGLGQT
CCCHHHHHCCCCCEEEEECCCCCEEEECCCCEECCCCCCCEEEEEECCEEEECCCCHHH
VAEYVAASLYPYGHSLKIGLTSYDLQEAITHLGKLEAEHLAQRRLATLSSGEQKRSIIAH
HHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHH
GLARRPIVLLADEPTSLLDMRARLLAYRVLRLEAEKGRIVVASTHDMLLAALYADHVVVI
HHCCCCEEEEECCCHHHHHHHHHHHHHHHHHEECCCCEEEEEEHHHHHHHHHHHCEEEEE
DKGVVVAQGTAGKVLSSELLEAVFSVKIAVAEVDGRTVPIPLEPL
ECCEEEECCCCCHHHHHHHHHHHHHHEEEEEECCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3301821; 2823072; 8202364; 9278503 [H]