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The map label for this gene is hpsA [H]

Identifier: 124027029

GI number: 124027029

Start: 113189

End: 113944

Strand: Direct

Name: hpsA [H]

Synonym: Hbut_0129

Alternate gene names: 124027029

Gene position: 113189-113944 (Clockwise)

Preceding gene: 124027027

Following gene: 124027032

Centisome position: 6.79

GC content: 58.33

Gene sequence:

>756_bases
GTGCCGCTGGAGATTATAGTCCTACACAGCCAGCCCCTACGCCCGGTGACTAGTGTGCCCTCCAGGCCACGCGTTGTGGA
GCTAGCTTCTAGGCAGCCAATCCTCCAGATAGCACTTGACCTAACCTCGCTCGAGGATGCCTTGCTCCTCGCCTCTAGGC
TCCGCCGTGGCCTCGGCGATTCGGGCTGGCTAGCTGAGGCCGGTACTCCACTCATAAAGTCTGAAGGACTGCGCTCAGTG
AGCCTCCTGGCCCGGGTGGTTGACCCAGTGCCCGTTGTAGCTGACATGAAGACAGCTGATACCGGCGCGCTCGAGGCGGA
GCTGGCATGCAAGGCAGGGGCTAGTGTCGTTACAGTACTGGGACTAGCGCCAGATGAGACTATAGAGGCTGCCGTAAGGA
CTGCTCATAACTGCGGTATGGCTGTAGCTGTCGACATGCTCGGGGTACGCAACGTCCTGGAGAGGGTTGAGGAGCTCGAG
CCTCTAGGAGTCGACATCATCGAACTCCATGTTGGCATTGATGTACAGAGGGCTCTCGGCCTTACGGCGGCTGAGCTGCG
CGGGCTAGTCTCAAAGATTGCCTCTAAGTTTAATGGCGTGGTAGCAGTAGCTGGCGGCCTCAACGAGTCCACAGCGCCAG
CAATGATTGAGGCAGGGGCATCGATAGCCATTGTCGGCGGCGCAATAACGAGGAGTAGGGATCCAGTAGGTATGGCTAAA
AAAATCCTCAAGGCGATACAGAGCGTTAGCCGGTAG

Upstream 100 bases:

>100_bases
CGGAGCCTATGAGCTGTATCGCTCTAAGCGTAAGATACCTAGCGGAAATACCGGCACCAACCAGGTAAAGCGGCAAAACC
CTCCCTCCGCCTTGAGAGTC

Downstream 100 bases:

>100_bases
AGGGCTCACGGTAAACTATCACCGGCACACGCTCCCCGGCATTATACCTGCGACCCTCAACCAACGCTATACCGTCAGCC
TCAACATTGCTAACTGTCAC

Product: hexulose-6-phosphate synthase

Products: NA

Alternate protein names: HPS; D-arabino-3-hexulose-6-phosphate formaldehyde lyase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MPLEIIVLHSQPLRPVTSVPSRPRVVELASRQPILQIALDLTSLEDALLLASRLRRGLGDSGWLAEAGTPLIKSEGLRSV
SLLARVVDPVPVVADMKTADTGALEAELACKAGASVVTVLGLAPDETIEAAVRTAHNCGMAVAVDMLGVRNVLERVEELE
PLGVDIIELHVGIDVQRALGLTAAELRGLVSKIASKFNGVVAVAGGLNESTAPAMIEAGASIAIVGGAITRSRDPVGMAK
KILKAIQSVSR

Sequences:

>Translated_251_residues
MPLEIIVLHSQPLRPVTSVPSRPRVVELASRQPILQIALDLTSLEDALLLASRLRRGLGDSGWLAEAGTPLIKSEGLRSV
SLLARVVDPVPVVADMKTADTGALEAELACKAGASVVTVLGLAPDETIEAAVRTAHNCGMAVAVDMLGVRNVLERVEELE
PLGVDIIELHVGIDVQRALGLTAAELRGLVSKIASKFNGVVAVAGGLNESTAPAMIEAGASIAIVGGAITRSRDPVGMAK
KILKAIQSVSR
>Mature_250_residues
PLEIIVLHSQPLRPVTSVPSRPRVVELASRQPILQIALDLTSLEDALLLASRLRRGLGDSGWLAEAGTPLIKSEGLRSVS
LLARVVDPVPVVADMKTADTGALEAELACKAGASVVTVLGLAPDETIEAAVRTAHNCGMAVAVDMLGVRNVLERVEELEP
LGVDIIELHVGIDVQRALGLTAAELRGLVSKIASKFNGVVAVAGGLNESTAPAMIEAGASIAIVGGAITRSRDPVGMAKK
ILKAIQSVSR

Specific function: Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate [H]

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. HPS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790006, Length=218, Percent_Identity=29.8165137614679, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017120
- InterPro:   IPR001754
- InterPro:   IPR011060
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6; PF00215 OMPdecase [H]

EC number: =4.1.2.43 [H]

Molecular weight: Translated: 26071; Mature: 25940

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLEIIVLHSQPLRPVTSVPSRPRVVELASRQPILQIALDLTSLEDALLLASRLRRGLGD
CCEEEEEECCCCCCHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
SGWLAEAGTPLIKSEGLRSVSLLARVVDPVPVVADMKTADTGALEAELACKAGASVVTVL
CCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHCCCCEEEEE
GLAPDETIEAAVRTAHNCGMAVAVDMLGVRNVLERVEELEPLGVDIIELHVGIDVQRALG
ECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHC
LTAAELRGLVSKIASKFNGVVAVAGGLNESTAPAMIEAGASIAIVGGAITRSRDPVGMAK
CCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCCEEEECCHHHCCCCCHHHHH
KILKAIQSVSR
HHHHHHHHHCC
>Mature Secondary Structure 
PLEIIVLHSQPLRPVTSVPSRPRVVELASRQPILQIALDLTSLEDALLLASRLRRGLGD
CEEEEEECCCCCCHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
SGWLAEAGTPLIKSEGLRSVSLLARVVDPVPVVADMKTADTGALEAELACKAGASVVTVL
CCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHCCCCEEEEE
GLAPDETIEAAVRTAHNCGMAVAVDMLGVRNVLERVEELEPLGVDIIELHVGIDVQRALG
ECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHC
LTAAELRGLVSKIASKFNGVVAVAGGLNESTAPAMIEAGASIAIVGGAITRSRDPVGMAK
CCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCCEEEECCHHHCCCCCHHHHH
KILKAIQSVSR
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA