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The map label for this gene is pyrF [H]

Identifier: 124027012

GI number: 124027012

Start: 100073

End: 100729

Strand: Reverse

Name: pyrF [H]

Synonym: Hbut_0112

Alternate gene names: 124027012

Gene position: 100729-100073 (Counterclockwise)

Preceding gene: 124027016

Following gene: 124027011

Centisome position: 6.04

GC content: 55.1

Gene sequence:

>657_bases
TTGACGCTCGTAGCTGCAATAGACCGTGATCCAGCCGAGGAACTAGTTTCGAAGCTATGCAGGGTGGTTGCAGGCTTCAA
GCTTGGCATTCCACTGCTGCTTAGGTATGGTGCAGCTTACGCGCATAGGCTGCGTAAACTCTGTAGAGACGCACTATGGA
TTGCTGATCTAAAGCTTGCAGACATAGGTAGCACCATGGTTGCTAGCGTGGAGCCTCTTCTCGGAGCCGTAGATGCCTTC
ATAGCGCATGCGGTGGTTGGGGTGGAGGGTGCACTTGACCAGCTGGCCAACACGCTGGAGGAACATGGAACTAAACTGGT
GCTCGTAGTAGCTATGAGTCATCCAGGCGCCTCCAGCCTTTACAATAAGCTCGTAGAAGACAATATTGAGGTGGCGAGGA
GGATCAGGGCGTGGGGCGTAGTTGCGCCAGCAACAATGCCGGAGCTCGTAGCGCTTGTGCGGAGTAGGCTGCCGGAAGTA
AAGGTGTTCTCGCCAGGAGTTGGCGCGCAAGGAGCGAAGCCTGGCGACGCCCTTTGCGCAGGAGCTGATTACGAGATAGT
TGGGAGACTAATTACGTCCTCGCCGGATCCTCTCGAAGTTGCTAAGAAGGTTCTGGCGGAGCAGAAAAAGAGACTTGAGA
GGTGCTGGAAGCCGTGA

Upstream 100 bases:

>100_bases
GAGGCGGTTACGCATATAGTGTCCGGCTATTAGCGCTCTCGCACAAACTACATTAATAAATGTAACCTTTGTGTAATGTT
TCCTCCATGGGAGTCGACTC

Downstream 100 bases:

>100_bases
ACAGCTATGCACTAGATCTAGCTGATGTGCTTGTCGAGGCTGGTGCGATAAGGTTTGGAGAGTTTAGACTCTCCAGCGGC
TCCACAAGCCCTATCTACAT

Product: orotidine-5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTLVAAIDRDPAEELVSKLCRVVAGFKLGIPLLLRYGAAYAHRLRKLCRDALWIADLKLADIGSTMVASVEPLLGAVDAF
IAHAVVGVEGALDQLANTLEEHGTKLVLVVAMSHPGASSLYNKLVEDNIEVARRIRAWGVVAPATMPELVALVRSRLPEV
KVFSPGVGAQGAKPGDALCAGADYEIVGRLITSSPDPLEVAKKVLAEQKKRLERCWKP

Sequences:

>Translated_218_residues
MTLVAAIDRDPAEELVSKLCRVVAGFKLGIPLLLRYGAAYAHRLRKLCRDALWIADLKLADIGSTMVASVEPLLGAVDAF
IAHAVVGVEGALDQLANTLEEHGTKLVLVVAMSHPGASSLYNKLVEDNIEVARRIRAWGVVAPATMPELVALVRSRLPEV
KVFSPGVGAQGAKPGDALCAGADYEIVGRLITSSPDPLEVAKKVLAEQKKRLERCWKP
>Mature_217_residues
TLVAAIDRDPAEELVSKLCRVVAGFKLGIPLLLRYGAAYAHRLRKLCRDALWIADLKLADIGSTMVASVEPLLGAVDAFI
AHAVVGVEGALDQLANTLEEHGTKLVLVVAMSHPGASSLYNKLVEDNIEVARRIRAWGVVAPATMPELVALVRSRLPEVK
VFSPGVGAQGAKPGDALCAGADYEIVGRLITSSPDPLEVAKKVLAEQKKRLERCWKP

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 23348; Mature: 23216

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVAAIDRDPAEELVSKLCRVVAGFKLGIPLLLRYGAAYAHRLRKLCRDALWIADLKLA
CCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIGSTMVASVEPLLGAVDAFIAHAVVGVEGALDQLANTLEEHGTKLVLVVAMSHPGASSL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHH
YNKLVEDNIEVARRIRAWGVVAPATMPELVALVRSRLPEVKVFSPGVGAQGAKPGDALCA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHCC
GADYEIVGRLITSSPDPLEVAKKVLAEQKKRLERCWKP
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLVAAIDRDPAEELVSKLCRVVAGFKLGIPLLLRYGAAYAHRLRKLCRDALWIADLKLA
CEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIGSTMVASVEPLLGAVDAFIAHAVVGVEGALDQLANTLEEHGTKLVLVVAMSHPGASSL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHH
YNKLVEDNIEVARRIRAWGVVAPATMPELVALVRSRLPEVKVFSPGVGAQGAKPGDALCA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHCC
GADYEIVGRLITSSPDPLEVAKKVLAEQKKRLERCWKP
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]