Click here to switch to the map view.

The map label for this gene is udp [H]

Identifier: 124026992

GI number: 124026992

Start: 82882

End: 83724

Strand: Direct

Name: udp [H]

Synonym: Hbut_0092

Alternate gene names: 124026992

Gene position: 82882-83724 (Clockwise)

Preceding gene: 124026990

Following gene: 124026993

Centisome position: 4.97

GC content: 57.77

Gene sequence:

>843_bases
GTGGAGAGGCCCTCGGCGAAAGCGCCAACCGTTGAGGGTAAAATGTACCATATCATGCTCGGCCCAGGCGAAATTCCGCC
CTACGTCCTCCTGCCAGGCGATCCAGGTAGGATAGACGATATAGTCGCGACGTGGGATGAATGGCGGGAGCTAGCATTTC
ACCGCGAGTATCGTAGTGTCAAGGGCAGGTATAAGGGTGTGGAAATAGGCGCTGTCAGCACTGGCATAGGCGGACCGTCA
ACTGCAATTGCCGTCGAGGAGCTGGCTAGGATAGGGGTACATACGTTCATCCGCGTGGGCACCACTGGCGCTATACAACC
GGATATAGAACTTGGAACAGTCATCATAGGCTATGCAGCTGTAAGATATGATGGTGCTAGTGGTGAGTATGCTCCGCCAG
AGTACCCCGCAGCTGCGACACCCGAGGTGGTTCTAGCTCTTGTTGAGGCTGCTGAGAGGCTCGGGGTACCATACCGTGTC
GGCGTGGTGGCCTCAACAGCAACATTCCACTTGGGGCAGAGCCGCCCAGGGTTCCGTGGGTACGAGTGGAGCCGTAGCAG
GGAGAGGCTAGCAGACCTACAGCGCATGGGTGTCCTCAGCTTCGAGATGGAGGCGGCGACGATATTCACTCTCGCGAGTC
TCTATGGGCTGCGGGCAGGCTGTGTCTGCGCCGCAATAGCCAACCGCGTGACCGACGAGTTTAAACCGGGGGTCGGGGTT
AGGGAGGCGATACTAGTGGCTAATGAGGCTGTGAGGATACTAGCCGAGGCCGACAGGGAAAAGGGCAGGAAGCCAGCTAG
TATAACAACGCTCTACAACGCCGTCAGAAAGCTGTACGGCTAG

Upstream 100 bases:

>100_bases
ATTCTTCTGGCACGGCTTGGCTACCCGGTTTCACAGCATAGTCTGGCCGGTACAGCTAAGGGGTTAGCCCCTCCTAACAG
ATTGTAGTGGTGTAGTAGCC

Downstream 100 bases:

>100_bases
TTGCAGGACAAGGATCGGTGCGGGGGCTTGCCTAGGGTCAAGGTGACAGTTGTTCCGGGCGGCAAGACTAGGATACTAGA
GTTTGGCGCCATGCCACGCG

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MERPSAKAPTVEGKMYHIMLGPGEIPPYVLLPGDPGRIDDIVATWDEWRELAFHREYRSVKGRYKGVEIGAVSTGIGGPS
TAIAVEELARIGVHTFIRVGTTGAIQPDIELGTVIIGYAAVRYDGASGEYAPPEYPAAATPEVVLALVEAAERLGVPYRV
GVVASTATFHLGQSRPGFRGYEWSRSRERLADLQRMGVLSFEMEAATIFTLASLYGLRAGCVCAAIANRVTDEFKPGVGV
REAILVANEAVRILAEADREKGRKPASITTLYNAVRKLYG

Sequences:

>Translated_280_residues
MERPSAKAPTVEGKMYHIMLGPGEIPPYVLLPGDPGRIDDIVATWDEWRELAFHREYRSVKGRYKGVEIGAVSTGIGGPS
TAIAVEELARIGVHTFIRVGTTGAIQPDIELGTVIIGYAAVRYDGASGEYAPPEYPAAATPEVVLALVEAAERLGVPYRV
GVVASTATFHLGQSRPGFRGYEWSRSRERLADLQRMGVLSFEMEAATIFTLASLYGLRAGCVCAAIANRVTDEFKPGVGV
REAILVANEAVRILAEADREKGRKPASITTLYNAVRKLYG
>Mature_280_residues
MERPSAKAPTVEGKMYHIMLGPGEIPPYVLLPGDPGRIDDIVATWDEWRELAFHREYRSVKGRYKGVEIGAVSTGIGGPS
TAIAVEELARIGVHTFIRVGTTGAIQPDIELGTVIIGYAAVRYDGASGEYAPPEYPAAATPEVVLALVEAAERLGVPYRV
GVVASTATFHLGQSRPGFRGYEWSRSRERLADLQRMGVLSFEMEAATIFTLASLYGLRAGCVCAAIANRVTDEFKPGVGV
REAILVANEAVRILAEADREKGRKPASITTLYNAVRKLYG

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=251, Percent_Identity=42.2310756972112, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1790844, Length=210, Percent_Identity=32.3809523809524, Blast_Score=94, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 30236; Mature: 30236

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERPSAKAPTVEGKMYHIMLGPGEIPPYVLLPGDPGRIDDIVATWDEWRELAFHREYRSV
CCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KGRYKGVEIGAVSTGIGGPSTAIAVEELARIGVHTFIRVGTTGAIQPDIELGTVIIGYAA
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHEEEEEEE
VRYDGASGEYAPPEYPAAATPEVVLALVEAAERLGVPYRVGVVASTATFHLGQSRPGFRG
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCCCC
YEWSRSRERLADLQRMGVLSFEMEAATIFTLASLYGLRAGCVCAAIANRVTDEFKPGVGV
CCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
REAILVANEAVRILAEADREKGRKPASITTLYNAVRKLYG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERPSAKAPTVEGKMYHIMLGPGEIPPYVLLPGDPGRIDDIVATWDEWRELAFHREYRSV
CCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KGRYKGVEIGAVSTGIGGPSTAIAVEELARIGVHTFIRVGTTGAIQPDIELGTVIIGYAA
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHEEEEEEE
VRYDGASGEYAPPEYPAAATPEVVLALVEAAERLGVPYRVGVVASTATFHLGQSRPGFRG
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCCCC
YEWSRSRERLADLQRMGVLSFEMEAATIFTLASLYGLRAGCVCAAIANRVTDEFKPGVGV
CCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
REAILVANEAVRILAEADREKGRKPASITTLYNAVRKLYG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2674901; 1379743; 9278503; 8506346; 8899705; 9661793; 7796917; 12499542 [H]