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The map label for this gene is cca [H]

Identifier: 124026917

GI number: 124026917

Start: 9157

End: 10611

Strand: Reverse

Name: cca [H]

Synonym: Hbut_0014

Alternate gene names: 124026917

Gene position: 10611-9157 (Counterclockwise)

Preceding gene: 124026919

Following gene: 124026916

Centisome position: 0.64

GC content: 55.53

Gene sequence:

>1455_bases
ATGAAGACCGGCATCGCCGGCAGCAGCGGCTGCCCCCATACCAAGGTCGAGAAACAAGTACTAGCTATGGTTGCACCCAC
CACGGGTGAGCGCGAAAAGGCGCGTAAAGCTGTAGAGGAGGCCACCAGGCTTCTCGACGCTGTACTGAAAGAACTTGGAG
TCAAGGACTATGAGGTACGTGTCGAGGGAAGCTATGCAAAGGATACCTGGCTTAGCGGCGAGCTAGACATAGACCTCTTC
ATACTCCTCCCGAGAAGCAAGTGCCTAGACCTGATACACGCCGGGCTGATAGACCAGATTGAGGAGAAACTGGCCAAGCT
CGGCTTGCGCACTGAACGCAGGTATGCCCAGCATCCATACGCAAGAGTACTAGTTCACAGCTACTGGGTTGAGGTGGTGC
CAGCTTGTCGCGTGGAGAAGCCTGGAGAGGTTGTTACTGCTGTTGACAGGACCCCCCTTCACACAAGGTATATACTTGGA
AGGCTAGAGCCCCATCAGCGTGACGAGGTTAGGCTTCTCAAGAGCTTCCTTAAGGGAATAGGTGTTTATGGTGCTGAAAT
AGCTGTGGAGGGATTTTCCGGCTACCTAGCAGAACTACTAATCGCAGCCTATGGCTGCTTTCGTAATGTTATAGCTGAGG
CTGCCAAGTGGAAACCACCAGTGATAGTTGACGTGAATGGGGCCGGCTATAGCCGTAAGGAGCTCCTGGAAAAGTTTGGC
GATAAACCCATGATAGTTGTTGATCCCGTAGACCCATCGAGGAATGCGGCAGCAGCAGTCTCGACACGATCACTTGCAGA
GCTTGTTCTCGCAGCAAAAATGTACCTCAGGGAACCCCGCATGGAGTTCTTCCACGTAGCCAGAACCCCCCCTACGACGC
CCCAACAAGCAGTAGCAAGTAGTGGTGAGCGTGTGTCAAACATGGTGCTACTACTCCTAGAGCCACCGCAGAGAGTGCCC
CCCGACACACTATGGGGGGTTGGCAAGCGAGCCCTAAGGCTAGCAGTAAACCTGCTAGAGAGATGGGGCTTCCACGTAAT
AGACTACAGGGTTACAGCATGCACAGAAGGGAGAATACTAGCCTGTATCGAGTTGGAAGAGAGGGTAACCCCGCCATACA
CACTGCACCGGGGCCCACCGGCCTGGAGTGGGCACGCGCTACGCTTCCTCGAGAAGTACGCCACCGATCCAAACGCCTAT
GGGCCCTGGATTGACGAGGAGGGCCGGCTGGTAGTGATTAGGGCTAGGAGGTACCAGGACGCTATACACCTCCTACGCGA
CCGGGCATGGGAATGGCTCCCCGGCAGCGCTAGTGGGTACAAGGTGGAGGTCCACCCGCTACTTCAGGGCCTCCTGGAGA
GGAGGATTGAGGAGTGTGAGCTGGAATGCCTAGCCAGCTTAGCCGTGAAGAAGCCAGCCTGGATGAGGAGGCTATACCAC
TCGCAAAAGCCATAG

Upstream 100 bases:

>100_bases
CTCATCACACAGCTTATGGCTGGTCAGCAATACCAGCCCTCTTCATCGCTCCTCTTTAAGACCTACCACGCCACCATACT
ATATGCGTACTGGTGGAGCC

Downstream 100 bases:

>100_bases
AAATAATCTGTAGCTACTATAGCGTGAGCATGGAGTCACCAGAGTGCCATAGGCTCATACACGACGCTAACTCCCTAGGA
ATCAGAGGAATCATACCCCT

Product: tRNA CCA-pyrophosphorylase

Products: NA

Alternate protein names: tRNA CCA-pyrophosphorylase; tRNA adenylyl-/cytidylyl- transferase; tRNA nucleotidyltransferase; tRNA-NT [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MKTGIAGSSGCPHTKVEKQVLAMVAPTTGEREKARKAVEEATRLLDAVLKELGVKDYEVRVEGSYAKDTWLSGELDIDLF
ILLPRSKCLDLIHAGLIDQIEEKLAKLGLRTERRYAQHPYARVLVHSYWVEVVPACRVEKPGEVVTAVDRTPLHTRYILG
RLEPHQRDEVRLLKSFLKGIGVYGAEIAVEGFSGYLAELLIAAYGCFRNVIAEAAKWKPPVIVDVNGAGYSRKELLEKFG
DKPMIVVDPVDPSRNAAAAVSTRSLAELVLAAKMYLREPRMEFFHVARTPPTTPQQAVASSGERVSNMVLLLLEPPQRVP
PDTLWGVGKRALRLAVNLLERWGFHVIDYRVTACTEGRILACIELEERVTPPYTLHRGPPAWSGHALRFLEKYATDPNAY
GPWIDEEGRLVVIRARRYQDAIHLLRDRAWEWLPGSASGYKVEVHPLLQGLLERRIEECELECLASLAVKKPAWMRRLYH
SQKP

Sequences:

>Translated_484_residues
MKTGIAGSSGCPHTKVEKQVLAMVAPTTGEREKARKAVEEATRLLDAVLKELGVKDYEVRVEGSYAKDTWLSGELDIDLF
ILLPRSKCLDLIHAGLIDQIEEKLAKLGLRTERRYAQHPYARVLVHSYWVEVVPACRVEKPGEVVTAVDRTPLHTRYILG
RLEPHQRDEVRLLKSFLKGIGVYGAEIAVEGFSGYLAELLIAAYGCFRNVIAEAAKWKPPVIVDVNGAGYSRKELLEKFG
DKPMIVVDPVDPSRNAAAAVSTRSLAELVLAAKMYLREPRMEFFHVARTPPTTPQQAVASSGERVSNMVLLLLEPPQRVP
PDTLWGVGKRALRLAVNLLERWGFHVIDYRVTACTEGRILACIELEERVTPPYTLHRGPPAWSGHALRFLEKYATDPNAY
GPWIDEEGRLVVIRARRYQDAIHLLRDRAWEWLPGSASGYKVEVHPLLQGLLERRIEECELECLASLAVKKPAWMRRLYH
SQKP
>Mature_484_residues
MKTGIAGSSGCPHTKVEKQVLAMVAPTTGEREKARKAVEEATRLLDAVLKELGVKDYEVRVEGSYAKDTWLSGELDIDLF
ILLPRSKCLDLIHAGLIDQIEEKLAKLGLRTERRYAQHPYARVLVHSYWVEVVPACRVEKPGEVVTAVDRTPLHTRYILG
RLEPHQRDEVRLLKSFLKGIGVYGAEIAVEGFSGYLAELLIAAYGCFRNVIAEAAKWKPPVIVDVNGAGYSRKELLEKFG
DKPMIVVDPVDPSRNAAAAVSTRSLAELVLAAKMYLREPRMEFFHVARTPPTTPQQAVASSGERVSNMVLLLLEPPQRVP
PDTLWGVGKRALRLAVNLLERWGFHVIDYRVTACTEGRILACIELEERVTPPYTLHRGPPAWSGHALRFLEKYATDPNAY
GPWIDEEGRLVVIRARRYQDAIHLLRDRAWEWLPGSASGYKVEVHPLLQGLLERRIEECELECLASLAVKKPAWMRRLYH
SQKP

Specific function: Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing

COG id: COG1746

COG function: function code J; tRNA nucleotidyltransferase (CCA-adding enzyme)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008229
- InterPro:   IPR002934
- InterPro:   IPR011068
- InterPro:   IPR015329 [H]

Pfam domain/function: PF01909 NTP_transf_2; PF09249 tRNA_NucTransf2 [H]

EC number: =2.7.7.21; =2.7.7.25 [H]

Molecular weight: Translated: 54466; Mature: 54466

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTGIAGSSGCPHTKVEKQVLAMVAPTTGEREKARKAVEEATRLLDAVLKELGVKDYEVR
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VEGSYAKDTWLSGELDIDLFILLPRSKCLDLIHAGLIDQIEEKLAKLGLRTERRYAQHPY
EECCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHH
ARVLVHSYWVEVVPACRVEKPGEVVTAVDRTPLHTRYILGRLEPHQRDEVRLLKSFLKGI
HHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHC
GVYGAEIAVEGFSGYLAELLIAAYGCFRNVIAEAAKWKPPVIVDVNGAGYSRKELLEKFG
CCCCHHEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHC
DKPMIVVDPVDPSRNAAAAVSTRSLAELVLAAKMYLREPRMEFFHVARTPPTTPQQAVAS
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCHHHHHHC
SGERVSNMVLLLLEPPQRVPPDTLWGVGKRALRLAVNLLERWGFHVIDYRVTACTEGRIL
CCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEE
ACIELEERVTPPYTLHRGPPAWSGHALRFLEKYATDPNAYGPWIDEEGRLVVIRARRYQD
EEEEHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECHHHHH
AIHLLRDRAWEWLPGSASGYKVEVHPLLQGLLERRIEECELECLASLAVKKPAWMRRLYH
HHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SQKP
CCCC
>Mature Secondary Structure
MKTGIAGSSGCPHTKVEKQVLAMVAPTTGEREKARKAVEEATRLLDAVLKELGVKDYEVR
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VEGSYAKDTWLSGELDIDLFILLPRSKCLDLIHAGLIDQIEEKLAKLGLRTERRYAQHPY
EECCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHH
ARVLVHSYWVEVVPACRVEKPGEVVTAVDRTPLHTRYILGRLEPHQRDEVRLLKSFLKGI
HHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHC
GVYGAEIAVEGFSGYLAELLIAAYGCFRNVIAEAAKWKPPVIVDVNGAGYSRKELLEKFG
CCCCHHEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHC
DKPMIVVDPVDPSRNAAAAVSTRSLAELVLAAKMYLREPRMEFFHVARTPPTTPQQAVAS
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCHHHHHHC
SGERVSNMVLLLLEPPQRVPPDTLWGVGKRALRLAVNLLERWGFHVIDYRVTACTEGRIL
CCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEE
ACIELEERVTPPYTLHRGPPAWSGHALRFLEKYATDPNAYGPWIDEEGRLVVIRARRYQD
EEEEHHHHCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECHHHHH
AIHLLRDRAWEWLPGSASGYKVEVHPLLQGLLERRIEECELECLASLAVKKPAWMRRLYH
HHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SQKP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA