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The map label for this gene is 124026909

Identifier: 124026909

GI number: 124026909

Start: 3689

End: 4414

Strand: Direct

Name: 124026909

Synonym: Hbut_0005

Alternate gene names: NA

Gene position: 3689-4414 (Clockwise)

Preceding gene: 124026908

Following gene: 124026914

Centisome position: 0.22

GC content: 52.89

Gene sequence:

>726_bases
TTGAAACTTGGGAAGGTGGAGAGACTACTGAGGAGCAGGGTTGAATCAGGAGAGAAGCTCTTCTTACTACTCTCCGACCC
CGAAAAACCAATATCGCCCAACACTGTCAAGCTCTTCGAAGAGAATGGCGCCGACGTACTACTAATTGGTGGTAGCCTAA
ACGTTACCCCCTACGATATAGATGAGTACATAGCTAGGCTTAGGGTTGAGGGTGTGAAGCTCCCCATAGTTCTGTTCCCG
GGCGGTCTCAACAACATCGCCAAGTCTGCCGACGCAATACTCTTCATGACTTTGATGAACAGCATGGATCCCTACTGGAT
TGTTGGCGCACAGGTAGCTGCAGCCCCAATCGTGTATAGGCTGGGCCTCGAGGCTATACCATCAGCATACATCATTGTAG
GGCACGGTGGTGCAGCTGGACATATAGGCCGCGCACTACCAATTCCATACGAGAATGGCTATATAGCAGCAGCCTACGCC
CTAGCTGCCGAGTACCTCGGAGCACGCCTAGTATACTTTGAGGCAGGCTCAGGTGCCCCAAAACCCGTACCTGTTGACGC
TGTAGCTGCTGCCAGCAAGGTTCTATCGCAAGCTTTGCTAGTAGTTGGTGGTGGTATACGGGAAGAGACCCTGGCCGCTG
AGAGGCTTAAGGCGGGAGCGGACGGCGTCGTAATTGGAACACTTGCAGAAAAGGATCCCGAGAAAGCACTGAGATCCTCT
CGGTAG

Upstream 100 bases:

>100_bases
GACGCATACCTGGAGGGCAGGATAGAGTATAAGTTTATCAAGGCCGAGGGCGAGAAGACCATCAGCCTAGAGGAGCTGAC
ATCTGAGGAGGGTGAAGTTG

Downstream 100 bases:

>100_bases
TTAAGAAGCGCTAGACTCCTCCCCGCCTGTGCCTGTACAGCTGACACTCCCTAGCTCAGCACCATACTTCTTCTTGAATG
CTTCCTCAGCGTCAACTCCC

Product: geranylgeranylglyceryl phosphate synthase-like protein

Products: NA

Alternate protein names: GGGP synthase; GGGPS; (S)-3-O-geranylgeranylglyceryl phosphate synthase; Phosphoglycerol geranylgeranyltransferase

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MKLGKVERLLRSRVESGEKLFLLLSDPEKPISPNTVKLFEENGADVLLIGGSLNVTPYDIDEYIARLRVEGVKLPIVLFP
GGLNNIAKSADAILFMTLMNSMDPYWIVGAQVAAAPIVYRLGLEAIPSAYIIVGHGGAAGHIGRALPIPYENGYIAAAYA
LAAEYLGARLVYFEAGSGAPKPVPVDAVAAASKVLSQALLVVGGGIREETLAAERLKAGADGVVIGTLAEKDPEKALRSS
R

Sequences:

>Translated_241_residues
MKLGKVERLLRSRVESGEKLFLLLSDPEKPISPNTVKLFEENGADVLLIGGSLNVTPYDIDEYIARLRVEGVKLPIVLFP
GGLNNIAKSADAILFMTLMNSMDPYWIVGAQVAAAPIVYRLGLEAIPSAYIIVGHGGAAGHIGRALPIPYENGYIAAAYA
LAAEYLGARLVYFEAGSGAPKPVPVDAVAAASKVLSQALLVVGGGIREETLAAERLKAGADGVVIGTLAEKDPEKALRSS
R
>Mature_241_residues
MKLGKVERLLRSRVESGEKLFLLLSDPEKPISPNTVKLFEENGADVLLIGGSLNVTPYDIDEYIARLRVEGVKLPIVLFP
GGLNNIAKSADAILFMTLMNSMDPYWIVGAQVAAAPIVYRLGLEAIPSAYIIVGHGGAAGHIGRALPIPYENGYIAAAYA
LAAEYLGARLVYFEAGSGAPKPVPVDAVAAASKVLSQALLVVGGGIREETLAAERLKAGADGVVIGTLAEKDPEKALRSS
R

Specific function: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membr

COG id: COG1646

COG function: function code R; Predicted phosphate-binding enzymes, TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GGGP synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GGGPS_HYPBU (A2BIS8)

Other databases:

- EMBL:   CP000493
- RefSeq:   YP_001012229.1
- ProteinModelPortal:   A2BIS8
- SMR:   A2BIS8
- STRING:   A2BIS8
- GeneID:   4781879
- GenomeReviews:   CP000493_GR
- KEGG:   hbu:Hbut_0005
- eggNOG:   arNOG05493
- HOGENOM:   HBG313841
- OMA:   ADAIFFM
- ProtClustDB:   PRK04169
- BioCyc:   HBUT415426:HBUT_0005-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00112
- InterPro:   IPR008205
- InterPro:   IPR010946
- Gene3D:   G3DSA:3.20.20.390
- TIGRFAMs:   TIGR01769
- TIGRFAMs:   TIGR01768

Pfam domain/function: PF01884 PcrB

EC number: =2.5.1.41

Molecular weight: Translated: 25407; Mature: 25407

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: BINDING 205-205

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGKVERLLRSRVESGEKLFLLLSDPEKPISPNTVKLFEENGADVLLIGGSLNVTPYDI
CCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCH
DEYIARLRVEGVKLPIVLFPGGLNNIAKSADAILFMTLMNSMDPYWIVGAQVAAAPIVYR
HHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
LGLEAIPSAYIIVGHGGAAGHIGRALPIPYENGYIAAAYALAAEYLGARLVYFEAGSGAP
HCHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCC
KPVPVDAVAAASKVLSQALLVVGGGIREETLAAERLKAGADGVVIGTLAEKDPEKALRSS
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCC
R
C
>Mature Secondary Structure
MKLGKVERLLRSRVESGEKLFLLLSDPEKPISPNTVKLFEENGADVLLIGGSLNVTPYDI
CCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCH
DEYIARLRVEGVKLPIVLFPGGLNNIAKSADAILFMTLMNSMDPYWIVGAQVAAAPIVYR
HHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
LGLEAIPSAYIIVGHGGAAGHIGRALPIPYENGYIAAAYALAAEYLGARLVYFEAGSGAP
HCHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCC
KPVPVDAVAAASKVLSQALLVVGGGIREETLAAERLKAGADGVVIGTLAEKDPEKALRSS
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA