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The map label for this gene is pab [H]

Identifier: 123967116

GI number: 123967116

Start: 1672366

End: 1673685

Strand: Direct

Name: pab [H]

Synonym: P9515_18831

Alternate gene names: 123967116

Gene position: 1672366-1673685 (Clockwise)

Preceding gene: 123967115

Following gene: 123967117

Centisome position: 98.13

GC content: 29.02

Gene sequence:

>1320_bases
ATGAATATTAAAACAAAAAAATTATCTAAGTGGATTGATCCAGAATTAATTGCAAATCATTTGGCCTTGAAATTTGGAGA
ACATGGGTTGTCCTGGTTAGATAGTGATGGAAAAGATAATGGGAAATGGTCAATAATGGGAGTGAACCCAAAAAAAATAA
TTTCTTCAGGAAATATAAATAATTTAGATATTGGTAATAACCCTTTTTTAAAATTAAAAAAAATTGAGAAAGGTTTTTGG
ATTGGATGGCTCAACTTTGAAGCTGGGGCTTATATTGAGCCAAAAAATCCATGGAAAAATCATGAAATATCTACTTTATG
GATTGCATCGTATGATCCAATTATAAAATTTAATCTAATTTCAAATGAAATACTGCTTGAGGGAACAAATTCTGCTGAAT
TAAGTAAATATGAAAAAATAATTTATGATATCGATCCTGAAAAAGAAAAAAATTCTATAAATAAAATTTTTAAATTTGAT
TTTTCAAAAATTAATTTACTAAAAATAAGCAATCAATTTCAGAAAAATATTTTAAGAATTAAGCAATTAATATCTATAGG
AGACATTTTTCAGGCAAATCTAACAACAAAATGTGAAGTTGAAGCTTTAGAAACTTTTAGTTATCTAAATTTATATTTAA
AAATAAGAAGCAAACTACCTGCGCCTTTTGGAGGAATAATAATAAATAAATCAAAGGGTATTAACGAAGCAGTATTATCA
ACCTCCCCTGAAAGATTTTTAAAAATAGACAAAGAGGGATATGTTGAATCAAGACCTATCAAAGGCACAAGGTCTAGACA
TCAAGATGAAAACCAAGATGCGTTAAATGCCATAGATTTGATAACTAATGAGAAAGATAGAGCTGAAAATATTATGATTG
TAGACCTCTTGAGAAATGATTTGAGCAAAGTATGCGAAGTAGGAAGTATTGAAGTGCCGGAGATATTAAAACTTGAAAGT
TATTTAAAAGTCCATCATCTTACATCTGTGATTAGAGGAAAGTTAAAAAAAAATAAAAGTTGGGTAGACTTACTAATTGC
TTGTTGGCCAGGGGGTTCTATCACAGGTGCTCCAAAATTAAGGTCCTGCCAAAGACTTTTTGAAATAGAAAATAGTAGCA
GAGGACCTTATTGTGGATCCTTTATAAAATTAGACTGGCATGGAGAATTTGATAGCAATATACTCATAAGATCATTTATC
GTAAAAAATCAGAAAATTCAAATATCTGCTGGATGCGGAATAGTAAATGATTCTGATCCAAAAGAGGAATTAAACGAACT
AAAATGGAAACTTTTACCTTTAATTGATTCATTGAAATGA

Upstream 100 bases:

>100_bases
AAAACATGGAGTTGTTATTCAGGTAATTTAAAACCCTGTGGGAAATGTGATAGTTGCAGAATAAGACAAACAGCCTATAA
AAAATGGCAAATTAAACAAA

Downstream 100 bases:

>100_bases
CGATAAGTATAGGCTGGCATAAAGATCAATGGCTAAAAATTGAAGATATTTGTATCTCAGCAAATGATAGAGGTCTAAAG
TTTGGCGATGGAATATTCGA

Product: putative p-aminobenzoate synthetase

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MNIKTKKLSKWIDPELIANHLALKFGEHGLSWLDSDGKDNGKWSIMGVNPKKIISSGNINNLDIGNNPFLKLKKIEKGFW
IGWLNFEAGAYIEPKNPWKNHEISTLWIASYDPIIKFNLISNEILLEGTNSAELSKYEKIIYDIDPEKEKNSINKIFKFD
FSKINLLKISNQFQKNILRIKQLISIGDIFQANLTTKCEVEALETFSYLNLYLKIRSKLPAPFGGIIINKSKGINEAVLS
TSPERFLKIDKEGYVESRPIKGTRSRHQDENQDALNAIDLITNEKDRAENIMIVDLLRNDLSKVCEVGSIEVPEILKLES
YLKVHHLTSVIRGKLKKNKSWVDLLIACWPGGSITGAPKLRSCQRLFEIENSSRGPYCGSFIKLDWHGEFDSNILIRSFI
VKNQKIQISAGCGIVNDSDPKEELNELKWKLLPLIDSLK

Sequences:

>Translated_439_residues
MNIKTKKLSKWIDPELIANHLALKFGEHGLSWLDSDGKDNGKWSIMGVNPKKIISSGNINNLDIGNNPFLKLKKIEKGFW
IGWLNFEAGAYIEPKNPWKNHEISTLWIASYDPIIKFNLISNEILLEGTNSAELSKYEKIIYDIDPEKEKNSINKIFKFD
FSKINLLKISNQFQKNILRIKQLISIGDIFQANLTTKCEVEALETFSYLNLYLKIRSKLPAPFGGIIINKSKGINEAVLS
TSPERFLKIDKEGYVESRPIKGTRSRHQDENQDALNAIDLITNEKDRAENIMIVDLLRNDLSKVCEVGSIEVPEILKLES
YLKVHHLTSVIRGKLKKNKSWVDLLIACWPGGSITGAPKLRSCQRLFEIENSSRGPYCGSFIKLDWHGEFDSNILIRSFI
VKNQKIQISAGCGIVNDSDPKEELNELKWKLLPLIDSLK
>Mature_439_residues
MNIKTKKLSKWIDPELIANHLALKFGEHGLSWLDSDGKDNGKWSIMGVNPKKIISSGNINNLDIGNNPFLKLKKIEKGFW
IGWLNFEAGAYIEPKNPWKNHEISTLWIASYDPIIKFNLISNEILLEGTNSAELSKYEKIIYDIDPEKEKNSINKIFKFD
FSKINLLKISNQFQKNILRIKQLISIGDIFQANLTTKCEVEALETFSYLNLYLKIRSKLPAPFGGIIINKSKGINEAVLS
TSPERFLKIDKEGYVESRPIKGTRSRHQDENQDALNAIDLITNEKDRAENIMIVDLLRNDLSKVCEVGSIEVPEILKLES
YLKVHHLTSVIRGKLKKNKSWVDLLIACWPGGSITGAPKLRSCQRLFEIENSSRGPYCGSFIKLDWHGEFDSNILIRSFI
VKNQKIQISAGCGIVNDSDPKEELNELKWKLLPLIDSLK

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=255, Percent_Identity=38.8235294117647, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1787518, Length=266, Percent_Identity=31.5789473684211, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1786809, Length=199, Percent_Identity=26.1306532663317, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=427, Percent_Identity=27.1662763466042, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324361, Length=283, Percent_Identity=29.3286219081272, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 49981; Mature: 49981

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKTKKLSKWIDPELIANHLALKFGEHGLSWLDSDGKDNGKWSIMGVNPKKIISSGNIN
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHCCCCCC
NLDIGNNPFLKLKKIEKGFWIGWLNFEAGAYIEPKNPWKNHEISTLWIASYDPIIKFNLI
EEECCCCCCEEEEEECCCEEEEEEEECCCEEECCCCCCCCCCEEEEEEECCCCEEEEEEE
SNEILLEGTNSAELSKYEKIIYDIDPEKEKNSINKIFKFDFSKINLLKISNQFQKNILRI
CCEEEEECCCCHHHHHHHHEEEECCCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHH
KQLISIGDIFQANLTTKCEVEALETFSYLNLYLKIRSKLPAPFGGIIINKSKGINEAVLS
HHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHC
TSPERFLKIDKEGYVESRPIKGTRSRHQDENQDALNAIDLITNEKDRAENIMIVDLLRND
CCCHHHEEECCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCHHCCEEEHHHHHHH
LSKVCEVGSIEVPEILKLESYLKVHHLTSVIRGKLKKNKSWVDLLIACWPGGSITGAPKL
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHH
RSCQRLFEIENSSRGPYCGSFIKLDWHGEFDSNILIRSFIVKNQKIQISAGCGIVNDSDP
HHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCEEEHHHCCCCEEEEEECCCCCCCCCH
KEELNELKWKLLPLIDSLK
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIKTKKLSKWIDPELIANHLALKFGEHGLSWLDSDGKDNGKWSIMGVNPKKIISSGNIN
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHCCCCCC
NLDIGNNPFLKLKKIEKGFWIGWLNFEAGAYIEPKNPWKNHEISTLWIASYDPIIKFNLI
EEECCCCCCEEEEEECCCEEEEEEEECCCEEECCCCCCCCCCEEEEEEECCCCEEEEEEE
SNEILLEGTNSAELSKYEKIIYDIDPEKEKNSINKIFKFDFSKINLLKISNQFQKNILRI
CCEEEEECCCCHHHHHHHHEEEECCCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHH
KQLISIGDIFQANLTTKCEVEALETFSYLNLYLKIRSKLPAPFGGIIINKSKGINEAVLS
HHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHC
TSPERFLKIDKEGYVESRPIKGTRSRHQDENQDALNAIDLITNEKDRAENIMIVDLLRND
CCCHHHEEECCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCHHCCEEEHHHHHHH
LSKVCEVGSIEVPEILKLESYLKVHHLTSVIRGKLKKNKSWVDLLIACWPGGSITGAPKL
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHH
RSCQRLFEIENSSRGPYCGSFIKLDWHGEFDSNILIRSFIVKNQKIQISAGCGIVNDSDP
HHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCEEEHHHCCCCEEEEEECCCCCCCCCH
KEELNELKWKLLPLIDSLK
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]