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The map label for this gene is ho1 [H]

Identifier: 123967014

GI number: 123967014

Start: 1566983

End: 1567693

Strand: Reverse

Name: ho1 [H]

Synonym: P9515_17811

Alternate gene names: 123967014

Gene position: 1567693-1566983 (Counterclockwise)

Preceding gene: 123967015

Following gene: 123967013

Centisome position: 91.99

GC content: 29.96

Gene sequence:

>711_bases
ATGGCAGTTGCTCTTGCAGGACAATTAAGAGAAGGGACAAAAAAGTCCCACACAATGGCTGAAAATACTGGCTTCGTAGC
TTGTTTTTTAAAAGGCGTTGTTGAAAAAAAATCATATAGAAAACTAATAAGTGATTTATATTTTGTTTATCAAGCGATGG
AAGAAGAAATAGAAAGATTGGTTAAGGAGGAACATCCTGTAATAAAACCTATTGGATTTAAATCATTATTTAGAACAGAA
ACACTTGAGAATGATCTGAAATTTTATTTTGGAGATGATTGGAAAAATGAAATTAATATTTCTAAATCGGCAGAAGAATA
TGTTAAACGAATACATCTTGTGGCACAAACATCGCCAGAATTATTGGTTGGCCATCACTATACACGATATATAGGAGATC
TATCTGGCGGTCAAATTTTAAAAAAAATAGCAAAAAAAGCTTTAAATTTGGATGGAAATAATGGTTTGAATTTTTATGAA
TTTAAAAATATTGGTGACGAAAAAAAATTTAAAGAAGAATATTCTAAGACTTTAAATCAACTCCCAATAAATCAAACTAT
TGCTGATGAAATTATCGATGAAGCCAATAAAGCCTTTACTTATAATATGAAAATGTTTAAGGAGCTAGAGGGAAACTTGA
TTGGTGTATTAGGTAAAATTGTTTTTAATTACCTCACAAAGAAAGTGAGGAAGGGAAGTACAGAAACTTAA

Upstream 100 bases:

>100_bases
TTACAATTTATTCTCTACAACATCCACTGGTAACAAAAATTAGTTGTTTTATCTATTTTCCTTGTACATTACATATATGT
ACAAATCAAAAAATACATAA

Downstream 100 bases:

>100_bases
TATTTATGTTTGACTCATTAAAAAATTTTTTAAAAAAAAGTATTGAAGATTTAGATGGTAAAGAATTAGAAATATCAAAG
GAATTTCAAGAATATCATAA

Product: Heme oxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MAVALAGQLREGTKKSHTMAENTGFVACFLKGVVEKKSYRKLISDLYFVYQAMEEEIERLVKEEHPVIKPIGFKSLFRTE
TLENDLKFYFGDDWKNEINISKSAEEYVKRIHLVAQTSPELLVGHHYTRYIGDLSGGQILKKIAKKALNLDGNNGLNFYE
FKNIGDEKKFKEEYSKTLNQLPINQTIADEIIDEANKAFTYNMKMFKELEGNLIGVLGKIVFNYLTKKVRKGSTET

Sequences:

>Translated_236_residues
MAVALAGQLREGTKKSHTMAENTGFVACFLKGVVEKKSYRKLISDLYFVYQAMEEEIERLVKEEHPVIKPIGFKSLFRTE
TLENDLKFYFGDDWKNEINISKSAEEYVKRIHLVAQTSPELLVGHHYTRYIGDLSGGQILKKIAKKALNLDGNNGLNFYE
FKNIGDEKKFKEEYSKTLNQLPINQTIADEIIDEANKAFTYNMKMFKELEGNLIGVLGKIVFNYLTKKVRKGSTET
>Mature_235_residues
AVALAGQLREGTKKSHTMAENTGFVACFLKGVVEKKSYRKLISDLYFVYQAMEEEIERLVKEEHPVIKPIGFKSLFRTET
LENDLKFYFGDDWKNEINISKSAEEYVKRIHLVAQTSPELLVGHHYTRYIGDLSGGQILKKIAKKALNLDGNNGLNFYEF
KNIGDEKKFKEEYSKTLNQLPINQTIADEIIDEANKAFTYNMKMFKELEGNLIGVLGKIVFNYLTKKVRKGSTET

Specific function: Catalyzes the opening of the heme ring with the release of iron. Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae [H]

COG id: COG5398

COG function: function code P; Heme oxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme oxygenase family [H]

Homologues:

Organism=Homo sapiens, GI187761311, Length=208, Percent_Identity=46.1538461538462, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI187761309, Length=208, Percent_Identity=46.1538461538462, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI187761307, Length=208, Percent_Identity=46.1538461538462, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI8051608, Length=208, Percent_Identity=46.1538461538462, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI4504437, Length=212, Percent_Identity=44.811320754717, Blast_Score=189, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002051
- InterPro:   IPR016053
- InterPro:   IPR016084
- InterPro:   IPR018207 [H]

Pfam domain/function: PF01126 Heme_oxygenase [H]

EC number: =1.14.99.3 [H]

Molecular weight: Translated: 27065; Mature: 26934

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVALAGQLREGTKKSHTMAENTGFVACFLKGVVEKKSYRKLISDLYFVYQAMEEEIERL
CCEECCHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKEEHPVIKPIGFKSLFRTETLENDLKFYFGDDWKNEINISKSAEEYVKRIHLVAQTSPE
HHHCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
LLVGHHYTRYIGDLSGGQILKKIAKKALNLDGNNGLNFYEFKNIGDEKKFKEEYSKTLNQ
HHHCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHH
LPINQTIADEIIDEANKAFTYNMKMFKELEGNLIGVLGKIVFNYLTKKVRKGSTET
CCCCHHHHHHHHHHHHHEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AVALAGQLREGTKKSHTMAENTGFVACFLKGVVEKKSYRKLISDLYFVYQAMEEEIERL
CEECCHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKEEHPVIKPIGFKSLFRTETLENDLKFYFGDDWKNEINISKSAEEYVKRIHLVAQTSPE
HHHCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
LLVGHHYTRYIGDLSGGQILKKIAKKALNLDGNNGLNFYEFKNIGDEKKFKEEYSKTLNQ
HHHCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHH
LPINQTIADEIIDEANKAFTYNMKMFKELEGNLIGVLGKIVFNYLTKKVRKGSTET
CCCCHHHHHHHHHHHHHEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]