Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 123967000

GI number: 123967000

Start: 1554626

End: 1555897

Strand: Reverse

Name: mrdB [H]

Synonym: P9515_17671

Alternate gene names: 123967000

Gene position: 1555897-1554626 (Counterclockwise)

Preceding gene: 123967001

Following gene: 123966999

Centisome position: 91.3

GC content: 28.69

Gene sequence:

>1272_bases
ATGATCAACGAAATTTCTTTGCTACAGAATAAGAGATTTTTTCAAAAGAAAGATAAATTTGATCGAAAAAATTTTTTTTC
ACCTTTAGTTCTAATACCTTTAGTATTGGTTTTCATTTCAAGTATTTTAATAAAAAGTGTACAAATAGAATTTTTACAAT
CAGATTTTTTAAATCATCTTTTCACAGGCTTATTTGGCTATTTTTTAGCGATTTTGATTTCATACATACCAATTGAAAGA
ATTAGAAAATATTTGATCCCGTTTTATTTTTGTTCTTTAATTTCATTACTTTTGATTTATTTTTTTGGGCTCTCAATTTA
TGGAGCTCAAAGATGGCTTAGCTTAGGCATTTTTTCTTTTCAACCATCGGAAGTCGCTAAATTGAGTACGATTTTAATTC
TTGCTTTAGTGCTAGAAAAAAAATCTATTTCTTCTATAAAAGATCTACTATTTCCTTTTTTTATAGTGGTTGTTCCTTGG
TTGTTAATATTTTTTCAACCTGATTTAGGAACTTCTTTGGTTTTAATAGTATTGACTTTTGTAATGCTTTATTGGTCCAA
GATGCCCATAGAGTGGATACTCATTTTAGGATTTTGTCTTTTAACATCAGTATTCTATTTCGTTTCTCCAAACTTGCTTA
TTTTTTGGATTCCTTTTATGGGTTATTTAGCTTATAGGTCTTCTCAAAATAAAATTAGCTTCTCTATTTTTACATTAGCC
CTACATTCATTAGTTGTTAAGTTGACACCTATTATGTGGGAATTCGGCTTAAAAGATTATCAAAAAGATAGATTAATTTT
GTTCTTAGATCCCAATAGGGATCCATTAGGTGGGGGATATCATTTAATACAAAGTAAAATAGCAATTGGTTCCGGAGGAC
TTTTTGGTACTGGTTTATTAAATGGTAAACTGACAAATTTACAATTTATACCTGAACAACATACCGATTTTATATTTAGT
GCTTTAGGAGAGGAATTAGGCTTTTTAGGGTGCATACTGGTTCTTTTTTTATTTTTTATTTTGATTAGTCAACTCGTAAA
GATATCAAAAAATGCGAGAACTAATTTTGAGTCATTAATAGTTATTGGTATAGCTTCAACATTCTTATTTCAAATTATTA
TTAACTTATTCATGACTATTGGATTAGGCCCAGTAACAGGAATACCGCTACCTTTCATGAGTTATGGTAGGACTTCTTTA
TTGATTAATTTTATATGCATTGGCTTGGCATTATCTACATTAAATCGCTCTAGATCACTACGAAATAAATGA

Upstream 100 bases:

>100_bases
AGGGATTCCAATTTCAATCAGTGAACCAGATAAAGAAAGTTCTATTAGATTTAAAGAGTTGGCTCTATTAATTAAAAAAA
CATTTATTAATTAGCAATAA

Downstream 100 bases:

>100_bases
AATCTCAAATAACTATAAAGAAAATTCAAGATTTACTTTTGCAAGGATTACATACTACATATGTTGATGATGAGACTTCT
AGGCGGATTTGGTGGGCCTC

Product: cell division membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MINEISLLQNKRFFQKKDKFDRKNFFSPLVLIPLVLVFISSILIKSVQIEFLQSDFLNHLFTGLFGYFLAILISYIPIER
IRKYLIPFYFCSLISLLLIYFFGLSIYGAQRWLSLGIFSFQPSEVAKLSTILILALVLEKKSISSIKDLLFPFFIVVVPW
LLIFFQPDLGTSLVLIVLTFVMLYWSKMPIEWILILGFCLLTSVFYFVSPNLLIFWIPFMGYLAYRSSQNKISFSIFTLA
LHSLVVKLTPIMWEFGLKDYQKDRLILFLDPNRDPLGGGYHLIQSKIAIGSGGLFGTGLLNGKLTNLQFIPEQHTDFIFS
ALGEELGFLGCILVLFLFFILISQLVKISKNARTNFESLIVIGIASTFLFQIIINLFMTIGLGPVTGIPLPFMSYGRTSL
LINFICIGLALSTLNRSRSLRNK

Sequences:

>Translated_423_residues
MINEISLLQNKRFFQKKDKFDRKNFFSPLVLIPLVLVFISSILIKSVQIEFLQSDFLNHLFTGLFGYFLAILISYIPIER
IRKYLIPFYFCSLISLLLIYFFGLSIYGAQRWLSLGIFSFQPSEVAKLSTILILALVLEKKSISSIKDLLFPFFIVVVPW
LLIFFQPDLGTSLVLIVLTFVMLYWSKMPIEWILILGFCLLTSVFYFVSPNLLIFWIPFMGYLAYRSSQNKISFSIFTLA
LHSLVVKLTPIMWEFGLKDYQKDRLILFLDPNRDPLGGGYHLIQSKIAIGSGGLFGTGLLNGKLTNLQFIPEQHTDFIFS
ALGEELGFLGCILVLFLFFILISQLVKISKNARTNFESLIVIGIASTFLFQIIINLFMTIGLGPVTGIPLPFMSYGRTSL
LINFICIGLALSTLNRSRSLRNK
>Mature_423_residues
MINEISLLQNKRFFQKKDKFDRKNFFSPLVLIPLVLVFISSILIKSVQIEFLQSDFLNHLFTGLFGYFLAILISYIPIER
IRKYLIPFYFCSLISLLLIYFFGLSIYGAQRWLSLGIFSFQPSEVAKLSTILILALVLEKKSISSIKDLLFPFFIVVVPW
LLIFFQPDLGTSLVLIVLTFVMLYWSKMPIEWILILGFCLLTSVFYFVSPNLLIFWIPFMGYLAYRSSQNKISFSIFTLA
LHSLVVKLTPIMWEFGLKDYQKDRLILFLDPNRDPLGGGYHLIQSKIAIGSGGLFGTGLLNGKLTNLQFIPEQHTDFIFS
ALGEELGFLGCILVLFLFFILISQLVKISKNARTNFESLIVIGIASTFLFQIIINLFMTIGLGPVTGIPLPFMSYGRTSL
LINFICIGLALSTLNRSRSLRNK

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=361, Percent_Identity=34.3490304709141, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1786277, Length=346, Percent_Identity=31.2138728323699, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 48283; Mature: 48283

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure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CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]