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The map label for this gene is speD [H]

Identifier: 123966992

GI number: 123966992

Start: 1544821

End: 1545255

Strand: Reverse

Name: speD [H]

Synonym: P9515_17591

Alternate gene names: 123966992

Gene position: 1545255-1544821 (Counterclockwise)

Preceding gene: 123966993

Following gene: 123966990

Centisome position: 90.67

GC content: 29.66

Gene sequence:

>435_bases
ATGGATGTTCCCAAAAAAAATAAAACTTTTAAAGCATTTAATGATGAGAAGAAATTAATCTATAAAAGTAAGCATTTTTT
GTTAGAACTTTATAGATGTGATTATGAAAAATTGAATGATGAATCTTTTCTGCGTTGTACATTAAATAATGCTGCCAAAC
TAGCTAATGCAACAATCTTAAATCTAATAAGTAATAAATTTGAACCTCAGGGAGTTACAGCAATTGCTTTACTAGCTGAA
TCTCATCTTTCAATACATACATGGCCTGAAGCGCATTATTCTGCAGTTGATATTTTTACATGTGGCCAAAATATGAAGCC
CGATATTTCTTGTCAATACTTAATTCAAGCTTTAATGGCTGAAGAGCATCTCCTACGTGTAATTAATAGGAATCCTCCTT
TGGAAATACATAATCAAGTAAGAAAAATAATTTAA

Upstream 100 bases:

>100_bases
CGCATTTAGATACATTCAATCAATCTTTTATAAGCTCATCACAAATGATTCATTTATAATGGAAAAGTTGTAATTTTTAC
CTAACTTAAAAAATATATTA

Downstream 100 bases:

>100_bases
ATTTCGATATTTATCGATTTAGCTTGCCGCTGACTAAGCCTTCAAGATCTAGGCTGGTGCATTTGAATCCTAGGTTAGAA
AAATAGTTAATTAATTCATG

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MDVPKKNKTFKAFNDEKKLIYKSKHFLLELYRCDYEKLNDESFLRCTLNNAAKLANATILNLISNKFEPQGVTAIALLAE
SHLSIHTWPEAHYSAVDIFTCGQNMKPDISCQYLIQALMAEEHLLRVINRNPPLEIHNQVRKII

Sequences:

>Translated_144_residues
MDVPKKNKTFKAFNDEKKLIYKSKHFLLELYRCDYEKLNDESFLRCTLNNAAKLANATILNLISNKFEPQGVTAIALLAE
SHLSIHTWPEAHYSAVDIFTCGQNMKPDISCQYLIQALMAEEHLLRVINRNPPLEIHNQVRKII
>Mature_144_residues
MDVPKKNKTFKAFNDEKKLIYKSKHFLLELYRCDYEKLNDESFLRCTLNNAAKLANATILNLISNKFEPQGVTAIALLAE
SHLSIHTWPEAHYSAVDIFTCGQNMKPDISCQYLIQALMAEEHLLRVINRNPPLEIHNQVRKII

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 16627; Mature: 16627

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVPKKNKTFKAFNDEKKLIYKSKHFLLELYRCDYEKLNDESFLRCTLNNAAKLANATIL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCHHHHHHHHHH
NLISNKFEPQGVTAIALLAESHLSIHTWPEAHYSAVDIFTCGQNMKPDISCQYLIQALMA
HHHHCCCCCCCHHHHEEEHHCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
EEHLLRVINRNPPLEIHNQVRKII
HHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MDVPKKNKTFKAFNDEKKLIYKSKHFLLELYRCDYEKLNDESFLRCTLNNAAKLANATIL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCHHHHHHHHHH
NLISNKFEPQGVTAIALLAESHLSIHTWPEAHYSAVDIFTCGQNMKPDISCQYLIQALMA
HHHHCCCCCCCHHHHEEEHHCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
EEHLLRVINRNPPLEIHNQVRKII
HHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]