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The map label for this gene is alr [H]

Identifier: 123966942

GI number: 123966942

Start: 1511229

End: 1512428

Strand: Reverse

Name: alr [H]

Synonym: P9515_17091

Alternate gene names: 123966942

Gene position: 1512428-1511229 (Counterclockwise)

Preceding gene: 123966944

Following gene: 123966941

Centisome position: 88.75

GC content: 31.92

Gene sequence:

>1200_bases
ATGCAGATTTCCTTTAATAATCGAAAAAATAATGTGGATACTAATTTAAATTTTCAAGGAGAAATTGATCCAACTCAAAG
AGCATGGATAGAAGTAAGCAGAAAAGCAATAGAGGCTAACGTTAGGAAGTTAAGATCAAAATTAAAAAATAATTGTGAAT
TCATGGCAGTTGTGAAGGCTGATGGATATGGACATGATGCCAAAGTTGTATCTGAAAATGCGATTAGAGGTGGTGCTTCT
CAATTAGGAGTAGCAACCTTAAAGGAGGGAATAAAACTTCGCTCTTCAAGCATAAATGTCCCAATTCTTGTTCTTGGGAA
TCTTTATGCAAAAAAAGATTTATTAATATGTTTTAGAAATGATTTGATGCCAACTGTTAGTTCGATTAGGGAATGTTTAA
TTTGTAATGAAATAGGCAAGATCAATAATATGAAATTTTCGTTACATCTAAAAATTGATACTGGGATGTCAAGATTGGGA
TTTGAATGTGATGAATTCGTACAACAATTTAATAATATAAAATCTCTTAAAAATATAGATGTTAAGGGCATATATAGTCA
TCTTGCATGCGCAGATGAAAAGAATGCATTGAATCCCAAAAGTAGAACCCAATTACAAAGAGAAAAATTTCAAGAATTGT
TGAAACTTGTCAGTATTGATAATACAAAAAATATCAAGATTCATCTCGCAAATTCTGCTGGCATGATTCTTGGTAAAAAC
TTTCATTTTGATATGGTTCGCGTTGGATTGGCCATGTATGGTTATGATCCATTAATAAATACAACTGAAAAGTCGCTTCT
TAAACCTGCTTTATTTTTGAAGGCTAAAGTGACTTTTGTTCGAACTATTGAGAAAGGTGTTGGAGTAAGTTATGGAAATA
AATTTGTTAGTGATAGAAAAACAAAGTTAGCTGTCTTAAGTATTGGTTATGCTGACGGAATTATCAGGAGTCTCTCTGGT
AAAATAAGTTTAATTCATAATAAAAAACTTTATCCTCAGGTAGGATCCATAACAATGGATCAAATGATGGTAGATATTAC
AGATTCTGAGGATATTAAAGTAGGTAGTACTATGCTATTACTAGGATCTGATGGAGAACAAACAATTTCTCCGATTGATT
GGGCACATAAATGCGATAGTATTCCTTGGGAAATTCTTTGCTCTTTTAAAAACAGATTACCAAGAGTCCAAGTTGATTAG

Upstream 100 bases:

>100_bases
AAGAAGCATTTAAAACAAGTGTCTGGCTCATGCCAAAAATCATTTTACATGTCATGCTAGCGGTATATTTAATTAAGCGC
ATATAACTACGCAAACATTA

Downstream 100 bases:

>100_bases
ACATTTCGATTAGATAAATAATTTTGAAAATTTGCTAAAAAATTGATAATGTATAAGAACTGGAGAGGTGGCTGAGTGGT
TGAAAGCGGCTCCCTGCTAA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MQISFNNRKNNVDTNLNFQGEIDPTQRAWIEVSRKAIEANVRKLRSKLKNNCEFMAVVKADGYGHDAKVVSENAIRGGAS
QLGVATLKEGIKLRSSSINVPILVLGNLYAKKDLLICFRNDLMPTVSSIRECLICNEIGKINNMKFSLHLKIDTGMSRLG
FECDEFVQQFNNIKSLKNIDVKGIYSHLACADEKNALNPKSRTQLQREKFQELLKLVSIDNTKNIKIHLANSAGMILGKN
FHFDMVRVGLAMYGYDPLINTTEKSLLKPALFLKAKVTFVRTIEKGVGVSYGNKFVSDRKTKLAVLSIGYADGIIRSLSG
KISLIHNKKLYPQVGSITMDQMMVDITDSEDIKVGSTMLLLGSDGEQTISPIDWAHKCDSIPWEILCSFKNRLPRVQVD

Sequences:

>Translated_399_residues
MQISFNNRKNNVDTNLNFQGEIDPTQRAWIEVSRKAIEANVRKLRSKLKNNCEFMAVVKADGYGHDAKVVSENAIRGGAS
QLGVATLKEGIKLRSSSINVPILVLGNLYAKKDLLICFRNDLMPTVSSIRECLICNEIGKINNMKFSLHLKIDTGMSRLG
FECDEFVQQFNNIKSLKNIDVKGIYSHLACADEKNALNPKSRTQLQREKFQELLKLVSIDNTKNIKIHLANSAGMILGKN
FHFDMVRVGLAMYGYDPLINTTEKSLLKPALFLKAKVTFVRTIEKGVGVSYGNKFVSDRKTKLAVLSIGYADGIIRSLSG
KISLIHNKKLYPQVGSITMDQMMVDITDSEDIKVGSTMLLLGSDGEQTISPIDWAHKCDSIPWEILCSFKNRLPRVQVD
>Mature_399_residues
MQISFNNRKNNVDTNLNFQGEIDPTQRAWIEVSRKAIEANVRKLRSKLKNNCEFMAVVKADGYGHDAKVVSENAIRGGAS
QLGVATLKEGIKLRSSSINVPILVLGNLYAKKDLLICFRNDLMPTVSSIRECLICNEIGKINNMKFSLHLKIDTGMSRLG
FECDEFVQQFNNIKSLKNIDVKGIYSHLACADEKNALNPKSRTQLQREKFQELLKLVSIDNTKNIKIHLANSAGMILGKN
FHFDMVRVGLAMYGYDPLINTTEKSLLKPALFLKAKVTFVRTIEKGVGVSYGNKFVSDRKTKLAVLSIGYADGIIRSLSG
KISLIHNKKLYPQVGSITMDQMMVDITDSEDIKVGSTMLLLGSDGEQTISPIDWAHKCDSIPWEILCSFKNRLPRVQVD

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=341, Percent_Identity=29.9120234604106, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787439, Length=375, Percent_Identity=25.6, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 44619; Mature: 44619

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQISFNNRKNNVDTNLNFQGEIDPTQRAWIEVSRKAIEANVRKLRSKLKNNCEFMAVVKA
CEEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
DGYGHDAKVVSENAIRGGASQLGVATLKEGIKLRSSSINVPILVLGNLYAKKDLLICFRN
CCCCCCCCEECCHHCCCCCHHHHHHHHHHCCEEECCCCCCEEEEECCCCCCCCEEEEECC
DLMPTVSSIRECLICNEIGKINNMKFSLHLKIDTGMSRLGFECDEFVQQFNNIKSLKNID
CCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHCCC
VKGIYSHLACADEKNALNPKSRTQLQREKFQELLKLVSIDNTKNIKIHLANSAGMILGKN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECC
FHFDMVRVGLAMYGYDPLINTTEKSLLKPALFLKAKVTFVRTIEKGVGVSYGNKFVSDRK
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCC
TKLAVLSIGYADGIIRSLSGKISLIHNKKLYPQVGSITMDQMMVDITDSEDIKVGSTMLL
CEEEEEEECHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEHEEEEECCCCCEEECCEEEE
LGSDGEQTISPIDWAHKCDSIPWEILCSFKNRLPRVQVD
EECCCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MQISFNNRKNNVDTNLNFQGEIDPTQRAWIEVSRKAIEANVRKLRSKLKNNCEFMAVVKA
CEEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
DGYGHDAKVVSENAIRGGASQLGVATLKEGIKLRSSSINVPILVLGNLYAKKDLLICFRN
CCCCCCCCEECCHHCCCCCHHHHHHHHHHCCEEECCCCCCEEEEECCCCCCCCEEEEECC
DLMPTVSSIRECLICNEIGKINNMKFSLHLKIDTGMSRLGFECDEFVQQFNNIKSLKNID
CCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHCCC
VKGIYSHLACADEKNALNPKSRTQLQREKFQELLKLVSIDNTKNIKIHLANSAGMILGKN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECC
FHFDMVRVGLAMYGYDPLINTTEKSLLKPALFLKAKVTFVRTIEKGVGVSYGNKFVSDRK
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCC
TKLAVLSIGYADGIIRSLSGKISLIHNKKLYPQVGSITMDQMMVDITDSEDIKVGSTMLL
CEEEEEEECHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEHEEEEECCCCCEEECCEEEE
LGSDGEQTISPIDWAHKCDSIPWEILCSFKNRLPRVQVD
EECCCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]