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The map label for this gene is murA

Identifier: 123966694

GI number: 123966694

Start: 1296296

End: 1297672

Strand: Direct

Name: murA

Synonym: P9515_14611

Alternate gene names: 123966694

Gene position: 1296296-1297672 (Clockwise)

Preceding gene: 123966689

Following gene: 123966695

Centisome position: 76.07

GC content: 32.61

Gene sequence:

>1377_bases
ATGGTTTGCGAAAGCAACAATAAGTCATATCTTAAATCCCAAAATTTAAAGATTATTGGCAAAAATAGCTTAAGAGGGAA
TGTAAAAATAAGTGGTGCAAAGAATTCTGCATTAGTATTACTTGCAGCATCATTACTAACTGACGAAAAAATCATTTTAG
ATAATGTTCCTCTTCTGACTGATATTGAGAAAATGGGTAATATTCTTAAGAATTTAGGAGTAAAATTACATAATAAAGAT
CATCAATTAATAATTGATTCAAAAAATATATCCATACAAGAACTTCCATATGAGCTTGTAAATGGATTAAGAGCTAGTTT
CTTTTGTATAGGAGCATTATTAACAAGATTTGGAAAGGCTTCACTACCTTTACCCGGTGGCTGTAATATTGGTGAAAGAC
CTATAAACGAGCACATAAATGGGCTAAGGGCACTAGGTGCAGAAATTATTATTGAAAAAGAAGTCGTAAAAGCAAAACTA
ATCAAGAAGAAAAGTAAACTATTTGGTGCAAATATCAGATTAAATTGTCCCAGTGTTGGAGCTACTGAAACATTAATAAT
GGCAGCATCCTTAGCAGAAGGTAGAACTATAATAGAAAATGCGGCAAGGGAGCCTGAAATACAAGACTTATGTCAGATGT
TAAATAAAATGGGTGCAAAAATTTATGGTGCAGGTAAAGAAAAAATAATTATTGATGGAGTTCAAAAACTTCATGGATGT
TCTCACAAAGTAATTCCTGATAGAATAGAAGCTGGAACTTTTTTAATAGCAGCTGCTGCAACTTCATCCTCAATTACAAT
CTCTCCAGTAATCCCAAATCACTTAGAGGCAGTATTAAATAAGTTAGAAGAGAGTGGAAGTAAAATAGAAAAAAAAGGAA
ATTCGATTTCAATATCTGGGAAAAGTATCAAAGCTGTAAAAATCAAAACTGCTCCATTTCCAGGATTTCCTACAGACCTT
CAAGCTCCATTCATGGCTCTTATGACTATAGCTAAAGGAACATCAATGATCTCTGAAAGAATTTTTGAAAACAGAATGCA
TCACGTTAACCTATTAAATCAAATGGGGGCTGCCATAACAGTGGATGACAATACAGCGATTATAAATGGAGTTAAGAAAT
TAAAAGGAATGAATTTAGTTGGTTCAGACTTGAGATCCTCAGCCGCGTTAATAATAGCTGCTTTAATTTCTGAAAATATT
AGTCATATTTATGGTCTTGAGCATTTAGACAGAGGATATGAAAACTTTGAGTTTAAGTTAACCAAACTAGGAGCAAAAAT
CATAAGAGAAGTTGACGGTGGAATACAAACAAAATCGAAGAATTCTTCTGAGATTCACCCTACCAAAAATTTAGATATAA
ATTTTAATGTTGCCTAG

Upstream 100 bases:

>100_bases
ATATCTATACCCTTTACTATTACTTAATATTCTACACGTTACAGAAGCTGGACTTCCTATACTAATTTTGTCATCATTAA
ACCAATAAAAATTTTTCTTA

Downstream 100 bases:

>100_bases
TTCAAACATAAGCTACGTTTGCTAACGAAACACACCCTAAAAATATAAAAGATAATACTAAAAAACGAACTGACCAATAT
TTATTTAAACCTTTGATATT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MVCESNNKSYLKSQNLKIIGKNSLRGNVKISGAKNSALVLLAASLLTDEKIILDNVPLLTDIEKMGNILKNLGVKLHNKD
HQLIIDSKNISIQELPYELVNGLRASFFCIGALLTRFGKASLPLPGGCNIGERPINEHINGLRALGAEIIIEKEVVKAKL
IKKKSKLFGANIRLNCPSVGATETLIMAASLAEGRTIIENAAREPEIQDLCQMLNKMGAKIYGAGKEKIIIDGVQKLHGC
SHKVIPDRIEAGTFLIAAAATSSSITISPVIPNHLEAVLNKLEESGSKIEKKGNSISISGKSIKAVKIKTAPFPGFPTDL
QAPFMALMTIAKGTSMISERIFENRMHHVNLLNQMGAAITVDDNTAIINGVKKLKGMNLVGSDLRSSAALIIAALISENI
SHIYGLEHLDRGYENFEFKLTKLGAKIIREVDGGIQTKSKNSSEIHPTKNLDINFNVA

Sequences:

>Translated_458_residues
MVCESNNKSYLKSQNLKIIGKNSLRGNVKISGAKNSALVLLAASLLTDEKIILDNVPLLTDIEKMGNILKNLGVKLHNKD
HQLIIDSKNISIQELPYELVNGLRASFFCIGALLTRFGKASLPLPGGCNIGERPINEHINGLRALGAEIIIEKEVVKAKL
IKKKSKLFGANIRLNCPSVGATETLIMAASLAEGRTIIENAAREPEIQDLCQMLNKMGAKIYGAGKEKIIIDGVQKLHGC
SHKVIPDRIEAGTFLIAAAATSSSITISPVIPNHLEAVLNKLEESGSKIEKKGNSISISGKSIKAVKIKTAPFPGFPTDL
QAPFMALMTIAKGTSMISERIFENRMHHVNLLNQMGAAITVDDNTAIINGVKKLKGMNLVGSDLRSSAALIIAALISENI
SHIYGLEHLDRGYENFEFKLTKLGAKIIREVDGGIQTKSKNSSEIHPTKNLDINFNVA
>Mature_458_residues
MVCESNNKSYLKSQNLKIIGKNSLRGNVKISGAKNSALVLLAASLLTDEKIILDNVPLLTDIEKMGNILKNLGVKLHNKD
HQLIIDSKNISIQELPYELVNGLRASFFCIGALLTRFGKASLPLPGGCNIGERPINEHINGLRALGAEIIIEKEVVKAKL
IKKKSKLFGANIRLNCPSVGATETLIMAASLAEGRTIIENAAREPEIQDLCQMLNKMGAKIYGAGKEKIIIDGVQKLHGC
SHKVIPDRIEAGTFLIAAAATSSSITISPVIPNHLEAVLNKLEESGSKIEKKGNSISISGKSIKAVKIKTAPFPGFPTDL
QAPFMALMTIAKGTSMISERIFENRMHHVNLLNQMGAAITVDDNTAIINGVKKLKGMNLVGSDLRSSAALIIAALISENI
SHIYGLEHLDRGYENFEFKLTKLGAKIIREVDGGIQTKSKNSSEIHPTKNLDINFNVA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=416, Percent_Identity=46.1538461538462, Blast_Score=366, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_PROM5 (A2BY07)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001011775.1
- ProteinModelPortal:   A2BY07
- SMR:   A2BY07
- STRING:   A2BY07
- GeneID:   4720106
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_14611
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   PMAR167542:P9515ORF_1525-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 49516; Mature: 49516

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVCESNNKSYLKSQNLKIIGKNSLRGNVKISGAKNSALVLLAASLLTDEKIILDNVPLLT
CCCCCCCCCHHHCCCEEEEECCCCCCCEEEECCCCCEEEEEEHHHHCCCEEEECCCCHHH
DIEKMGNILKNLGVKLHNKDHQLIIDSKNISIQELPYELVNGLRASFFCIGALLTRFGKA
HHHHHHHHHHHCCCEEECCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
SLPLPGGCNIGERPINEHINGLRALGAEIIIEKEVVKAKLIKKKSKLFGANIRLNCPSVG
CCCCCCCCCCCCCCHHHHHHHHHHHCHHHEEHHHHHHHHHHHHHHHHCCCCEEEECCCCC
ATETLIMAASLAEGRTIIENAAREPEIQDLCQMLNKMGAKIYGAGKEKIIIDGVQKLHGC
CHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEEHHHHHHCCC
SHKVIPDRIEAGTFLIAAAATSSSITISPVIPNHLEAVLNKLEESGSKIEKKGNSISISG
CCCCCCCHHCCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHCCHHHHHCCCEEEECC
KSIKAVKIKTAPFPGFPTDLQAPFMALMTIAKGTSMISERIFENRMHHVNLLNQMGAAIT
CEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VDDNTAIINGVKKLKGMNLVGSDLRSSAALIIAALISENISHIYGLEHLDRGYENFEFKL
ECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEEEH
TKLGAKIIREVDGGIQTKSKNSSEIHPTKNLDINFNVA
HHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MVCESNNKSYLKSQNLKIIGKNSLRGNVKISGAKNSALVLLAASLLTDEKIILDNVPLLT
CCCCCCCCCHHHCCCEEEEECCCCCCCEEEECCCCCEEEEEEHHHHCCCEEEECCCCHHH
DIEKMGNILKNLGVKLHNKDHQLIIDSKNISIQELPYELVNGLRASFFCIGALLTRFGKA
HHHHHHHHHHHCCCEEECCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
SLPLPGGCNIGERPINEHINGLRALGAEIIIEKEVVKAKLIKKKSKLFGANIRLNCPSVG
CCCCCCCCCCCCCCHHHHHHHHHHHCHHHEEHHHHHHHHHHHHHHHHCCCCEEEECCCCC
ATETLIMAASLAEGRTIIENAAREPEIQDLCQMLNKMGAKIYGAGKEKIIIDGVQKLHGC
CHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEEHHHHHHCCC
SHKVIPDRIEAGTFLIAAAATSSSITISPVIPNHLEAVLNKLEESGSKIEKKGNSISISG
CCCCCCCHHCCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHCCHHHHHCCCEEEECC
KSIKAVKIKTAPFPGFPTDLQAPFMALMTIAKGTSMISERIFENRMHHVNLLNQMGAAIT
CEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VDDNTAIINGVKKLKGMNLVGSDLRSSAALIIAALISENISHIYGLEHLDRGYENFEFKL
ECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEEEH
TKLGAKIIREVDGGIQTKSKNSSEIHPTKNLDINFNVA
HHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA