Click here to switch to the map view.

The map label for this gene is ppnK [H]

Identifier: 123966663

GI number: 123966663

Start: 1268276

End: 1269184

Strand: Reverse

Name: ppnK [H]

Synonym: P9515_14301

Alternate gene names: 123966663

Gene position: 1269184-1268276 (Counterclockwise)

Preceding gene: 123966664

Following gene: 123966661

Centisome position: 74.47

GC content: 38.17

Gene sequence:

>909_bases
TTGGTACGTAAAGCTGGACTAATCGTCAATGATGGTAAAGAACTAGCTGTTCAAACAGCAATTTCAGTTCAAAAAAAATT
GGAGAAATCCAATTATGAAGTTGTAAGAGTAAGTAGTTCTGGAGGTATGGTTGGTTTTGCCAATCCTGATCAGCACGTTC
GTCCTTTGGGATACTCGAATTGTGTTCCTGAAGGTTTCGATTCGTCTATGGAGTTTGCGATTGTTCTGGGAGGAGACGGT
ACAGTACTTTCTGCTGCGCGACAGACAGCTCCTGCAAAAATTCCAATCCTTACAATTAATACTGGGCATTTAGGTTTTCT
TGCAGAAGCGTATCTTTCTAATCTAGAGGAAGCAGTTGATAAACTTATTGTTGGTAATTGGGAAATAGAAGAAAGAAAAA
GTTTGATTATTAGTGTAATGAGAGATGAGCAAAGAAGATGGGAATCTCTTTGCTTAAATGAAATGGCTCTTCATAGAGAA
CCTTTGACGAGTATGTGCCATTTTGAGATTTCAATAGGTAGACATGCACCAGTCGATATATCTGCTGATGGGGTTATACT
CTCTACTCCAACTGGCTCAACAGCTTATTCTTTAAGTGCTGGCGGTCCTGTTATTACGCCCGATTGCCCAGTAGTTCAAT
TAACTCCAATTGCTCCTCATTCTTTAGCTTCAAGGGCTTTAGTTTTTAATGATTCAGAACCAGTTACAGTTTTCCCAGCA
ACCCCTGAAAGGTTAGTTATGGTTGTTGATGGAAATGCCGGTTGTTATGTTTGGCCTGAAGATAGAGTTTTAATTAGAAA
AAGTAAACATTCAGTAAAGTTTATAAGACTTGAAGATCATGAATTTTTCCAAGTTTTGAGAAATAAATTAGGTTGGGGAT
TACCTCATGTGGGTAAACCTAATAAGTAA

Upstream 100 bases:

>100_bases
AATGATCTAAGATTCCTAGAACAGTTTTAAAATAATTAGTGTTTAAATTAGGTTTCTTAATCAATTTAGATTAAAATATT
AGTAGTTTGTAATTTATTGA

Downstream 100 bases:

>100_bases
TTTTAAGTTAAATTAGTTTTCTCCCTTTAAGCAAAAATACAGGATTGTTCGGATCCATTCTAATTCCCCCTGAAATACTT
AAACTTTTATAAGTCTGAAT

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 2 [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MVRKAGLIVNDGKELAVQTAISVQKKLEKSNYEVVRVSSSGGMVGFANPDQHVRPLGYSNCVPEGFDSSMEFAIVLGGDG
TVLSAARQTAPAKIPILTINTGHLGFLAEAYLSNLEEAVDKLIVGNWEIEERKSLIISVMRDEQRRWESLCLNEMALHRE
PLTSMCHFEISIGRHAPVDISADGVILSTPTGSTAYSLSAGGPVITPDCPVVQLTPIAPHSLASRALVFNDSEPVTVFPA
TPERLVMVVDGNAGCYVWPEDRVLIRKSKHSVKFIRLEDHEFFQVLRNKLGWGLPHVGKPNK

Sequences:

>Translated_302_residues
MVRKAGLIVNDGKELAVQTAISVQKKLEKSNYEVVRVSSSGGMVGFANPDQHVRPLGYSNCVPEGFDSSMEFAIVLGGDG
TVLSAARQTAPAKIPILTINTGHLGFLAEAYLSNLEEAVDKLIVGNWEIEERKSLIISVMRDEQRRWESLCLNEMALHRE
PLTSMCHFEISIGRHAPVDISADGVILSTPTGSTAYSLSAGGPVITPDCPVVQLTPIAPHSLASRALVFNDSEPVTVFPA
TPERLVMVVDGNAGCYVWPEDRVLIRKSKHSVKFIRLEDHEFFQVLRNKLGWGLPHVGKPNK
>Mature_302_residues
MVRKAGLIVNDGKELAVQTAISVQKKLEKSNYEVVRVSSSGGMVGFANPDQHVRPLGYSNCVPEGFDSSMEFAIVLGGDG
TVLSAARQTAPAKIPILTINTGHLGFLAEAYLSNLEEAVDKLIVGNWEIEERKSLIISVMRDEQRRWESLCLNEMALHRE
PLTSMCHFEISIGRHAPVDISADGVILSTPTGSTAYSLSAGGPVITPDCPVVQLTPIAPHSLASRALVFNDSEPVTVFPA
TPERLVMVVDGNAGCYVWPEDRVLIRKSKHSVKFIRLEDHEFFQVLRNKLGWGLPHVGKPNK

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=261, Percent_Identity=26.8199233716475, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1788968, Length=223, Percent_Identity=35.8744394618834, Blast_Score=146, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320794, Length=251, Percent_Identity=31.4741035856574, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6325068, Length=169, Percent_Identity=31.9526627218935, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322509, Length=245, Percent_Identity=26.530612244898, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573828, Length=247, Percent_Identity=27.9352226720648, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573830, Length=247, Percent_Identity=27.9352226720648, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28573832, Length=247, Percent_Identity=27.9352226720648, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161077047, Length=247, Percent_Identity=27.9352226720648, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28573826, Length=247, Percent_Identity=27.9352226720648, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281363321, Length=202, Percent_Identity=29.7029702970297, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24653424, Length=202, Percent_Identity=29.7029702970297, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI20129957, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI281363323, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24653422, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 32977; Mature: 32977

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRKAGLIVNDGKELAVQTAISVQKKLEKSNYEVVRVSSSGGMVGFANPDQHVRPLGYSN
CCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCCCC
CVPEGFDSSMEFAIVLGGDGTVLSAARQTAPAKIPILTINTGHLGFLAEAYLSNLEEAVD
CCCCCCCCCCEEEEEECCCCCEEHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
KLIVGNWEIEERKSLIISVMRDEQRRWESLCLNEMALHREPLTSMCHFEISIGRHAPVDI
HHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEE
SADGVILSTPTGSTAYSLSAGGPVITPDCPVVQLTPIAPHSLASRALVFNDSEPVTVFPA
CCCCEEEECCCCCCEEEECCCCCEECCCCCEEEEECCCCHHHHCEEEEECCCCCEEEEEC
TPERLVMVVDGNAGCYVWPEDRVLIRKSKHSVKFIRLEDHEFFQVLRNKLGWGLPHVGKP
CCCEEEEEEECCCCEEECCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCC
NK
CC
>Mature Secondary Structure
MVRKAGLIVNDGKELAVQTAISVQKKLEKSNYEVVRVSSSGGMVGFANPDQHVRPLGYSN
CCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCCCC
CVPEGFDSSMEFAIVLGGDGTVLSAARQTAPAKIPILTINTGHLGFLAEAYLSNLEEAVD
CCCCCCCCCCEEEEEECCCCCEEHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
KLIVGNWEIEERKSLIISVMRDEQRRWESLCLNEMALHREPLTSMCHFEISIGRHAPVDI
HHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEE
SADGVILSTPTGSTAYSLSAGGPVITPDCPVVQLTPIAPHSLASRALVFNDSEPVTVFPA
CCCCEEEECCCCCCEEEECCCCCEECCCCCEEEEECCCCHHHHCEEEEECCCCCEEEEEC
TPERLVMVVDGNAGCYVWPEDRVLIRKSKHSVKFIRLEDHEFFQVLRNKLGWGLPHVGKP
CCCEEEEEEECCCCEEECCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCC
NK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA