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The map label for this gene is ribD [H]

Identifier: 123966659

GI number: 123966659

Start: 1265059

End: 1266165

Strand: Reverse

Name: ribD [H]

Synonym: P9515_14261

Alternate gene names: 123966659

Gene position: 1266165-1265059 (Counterclockwise)

Preceding gene: 123966660

Following gene: 123966658

Centisome position: 74.3

GC content: 32.97

Gene sequence:

>1107_bases
ATGATTGAAATCAATGGTATTGACATAAAATGGATGAAAAGAGCTATATATTTGGCTTCTTTAGGTAAAGGAAGAACAAA
TCCTAATCCAATGGTTGGGGCAGTAATTTTGGATAAAAATGGAAATCTTATTTCAGAAGGATTTCATTCAAAGTCTGGGA
TGCCTCATGCAGAGGCAATGGCTTTCAATAACTTAAAAAAAAATGCAAGAGATGGGATACTTTATGTTAATTTAGAACCC
TGTTGCCATCACGGCAAAACACCTCCCTGTGTGGATAAAATAATTTCTTTTGGGATAAAGAAAGTATTTGTTTCTATTGA
AGATCCCGATAAAAGAGTTTCAGGAAAAGGTATAAAATTGCTAAAAGATTCTGGGATTGAAGTTCATTTAGGATTATGTG
AAAAAGAATCGACAGAATTAAATAAGTCTTTTATTCATAGGAATATTACTAATAACGCTTATGGAGTTTTGAAATGGGCA
ATGAGTATGGATGGAAGGGTTGGTCTGAAAAATGGTAAAAGTAAATGGATTACAAATAAAGATTCAAGATCATTAGTTCA
CTCTCATAGAGCTTGCTTTGATGCAATAGTCATTGGTGGTAATACACTAAGAAAAGATGATCCTCTTCTAACTTCTCGGG
GTAGAAGAAATCCCGAACCTTTGCGAGTAGTGTTCACAAAAACTTTAGATTTACCAGAAAAATCTAATTTTTGGGATTTT
AACCTAGCTAAGACTCTTGTTGTTTATGATAGTTCTTGTGCAGATAAAAATTTTCTTAAGAGAATTCCGGAGGGTGTAGA
GATTGAAGAATTATCCTCTGATAATCCTATATTGCTTTCAAATTTATTAGCAAAAAAAGGGTGTAATAATGTTTTATGGG
AATGTGGGCCTAAGTTAGCAACCTCAGCTATCAAAGCAGGTTGTATTCAAGAACTAATGACTTTTATCGCACCGAAGATA
TTAGGAGGTATAAGCAGCATGAACCCCTTCTCTGATTTTGAATTTACAGATATGGATCAAGTCTTTAATTTATGTAAATC
TGAAATTAACTTTATCGGGGACGATATTTTTGTAAAGAGTGCCATTAATTATAAAAAAGTTGTCTAG

Upstream 100 bases:

>100_bases
CCACTCAGATTATCTTTGTCAGGTGTTTTCTCGGATTTGCCAGTTCCTCCTTTCGTAGTAAAAGAATGGAGATCATTAGA
TTGATAACTAATTCGATAAG

Downstream 100 bases:

>100_bases
TTAAAATACCGTTCGGTTCTTACCCAAAAAAAAATTATACAGGGACAGAACTTGTTCGTTTAGTTTATAATATATTCACA
AACAACACTAATCATGCCAA

Product: putative diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MIEINGIDIKWMKRAIYLASLGKGRTNPNPMVGAVILDKNGNLISEGFHSKSGMPHAEAMAFNNLKKNARDGILYVNLEP
CCHHGKTPPCVDKIISFGIKKVFVSIEDPDKRVSGKGIKLLKDSGIEVHLGLCEKESTELNKSFIHRNITNNAYGVLKWA
MSMDGRVGLKNGKSKWITNKDSRSLVHSHRACFDAIVIGGNTLRKDDPLLTSRGRRNPEPLRVVFTKTLDLPEKSNFWDF
NLAKTLVVYDSSCADKNFLKRIPEGVEIEELSSDNPILLSNLLAKKGCNNVLWECGPKLATSAIKAGCIQELMTFIAPKI
LGGISSMNPFSDFEFTDMDQVFNLCKSEINFIGDDIFVKSAINYKKVV

Sequences:

>Translated_368_residues
MIEINGIDIKWMKRAIYLASLGKGRTNPNPMVGAVILDKNGNLISEGFHSKSGMPHAEAMAFNNLKKNARDGILYVNLEP
CCHHGKTPPCVDKIISFGIKKVFVSIEDPDKRVSGKGIKLLKDSGIEVHLGLCEKESTELNKSFIHRNITNNAYGVLKWA
MSMDGRVGLKNGKSKWITNKDSRSLVHSHRACFDAIVIGGNTLRKDDPLLTSRGRRNPEPLRVVFTKTLDLPEKSNFWDF
NLAKTLVVYDSSCADKNFLKRIPEGVEIEELSSDNPILLSNLLAKKGCNNVLWECGPKLATSAIKAGCIQELMTFIAPKI
LGGISSMNPFSDFEFTDMDQVFNLCKSEINFIGDDIFVKSAINYKKVV
>Mature_368_residues
MIEINGIDIKWMKRAIYLASLGKGRTNPNPMVGAVILDKNGNLISEGFHSKSGMPHAEAMAFNNLKKNARDGILYVNLEP
CCHHGKTPPCVDKIISFGIKKVFVSIEDPDKRVSGKGIKLLKDSGIEVHLGLCEKESTELNKSFIHRNITNNAYGVLKWA
MSMDGRVGLKNGKSKWITNKDSRSLVHSHRACFDAIVIGGNTLRKDDPLLTSRGRRNPEPLRVVFTKTLDLPEKSNFWDF
NLAKTLVVYDSSCADKNFLKRIPEGVEIEELSSDNPILLSNLLAKKGCNNVLWECGPKLATSAIKAGCIQELMTFIAPKI
LGGISSMNPFSDFEFTDMDQVFNLCKSEINFIGDDIFVKSAINYKKVV

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=355, Percent_Identity=33.8028169014084, Blast_Score=206, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40864; Mature: 40864

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEINGIDIKWMKRAIYLASLGKGRTNPNPMVGAVILDKNGNLISEGFHSKSGMPHAEAM
CEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHCCCCCCCCCCHHHHH
AFNNLKKNARDGILYVNLEPCCHHGKTPPCVDKIISFGIKKVFVSIEDPDKRVSGKGIKL
HHHHHHHCCCCCEEEEEECHHHCCCCCCHHHHHHHHHCHHEEEEEECCCCCCCCCCCEEE
LKDSGIEVHLGLCEKESTELNKSFIHRNITNNAYGVLKWAMSMDGRVGLKNGKSKWITNK
EECCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHEEHHHHHCCCCCEECCCCCCCCCCCC
DSRSLVHSHRACFDAIVIGGNTLRKDDPLLTSRGRRNPEPLRVVFTKTLDLPEKSNFWDF
CHHHHHHHHHHHHHEEEECCCCCCCCCCCHHCCCCCCCCCEEEEEEEECCCCCCCCCCCC
NLAKTLVVYDSSCADKNFLKRIPEGVEIEELSSDNPILLSNLLAKKGCNNVLWECGPKLA
CCEEEEEEECCCCCCHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHCCCCCHHHHCCHHHH
TSAIKAGCIQELMTFIAPKILGGISSMNPFSDFEFTDMDQVFNLCKSEINFIGDDIFVKS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
AINYKKVV
CCCHHCCC
>Mature Secondary Structure
MIEINGIDIKWMKRAIYLASLGKGRTNPNPMVGAVILDKNGNLISEGFHSKSGMPHAEAM
CEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHCCCCCCCCCCHHHHH
AFNNLKKNARDGILYVNLEPCCHHGKTPPCVDKIISFGIKKVFVSIEDPDKRVSGKGIKL
HHHHHHHCCCCCEEEEEECHHHCCCCCCHHHHHHHHHCHHEEEEEECCCCCCCCCCCEEE
LKDSGIEVHLGLCEKESTELNKSFIHRNITNNAYGVLKWAMSMDGRVGLKNGKSKWITNK
EECCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHEEHHHHHCCCCCEECCCCCCCCCCCC
DSRSLVHSHRACFDAIVIGGNTLRKDDPLLTSRGRRNPEPLRVVFTKTLDLPEKSNFWDF
CHHHHHHHHHHHHHEEEECCCCCCCCCCCHHCCCCCCCCCEEEEEEEECCCCCCCCCCCC
NLAKTLVVYDSSCADKNFLKRIPEGVEIEELSSDNPILLSNLLAKKGCNNVLWECGPKLA
CCEEEEEEECCCCCCHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHCCCCCHHHHCCHHHH
TSAIKAGCIQELMTFIAPKILGGISSMNPFSDFEFTDMDQVFNLCKSEINFIGDDIFVKS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
AINYKKVV
CCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]