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The map label for this gene is engD [H]

Identifier: 123966535

GI number: 123966535

Start: 1141913

End: 1143004

Strand: Reverse

Name: engD [H]

Synonym: P9515_13021

Alternate gene names: 123966535

Gene position: 1143004-1141913 (Counterclockwise)

Preceding gene: 123966542

Following gene: 123966529

Centisome position: 67.07

GC content: 31.96

Gene sequence:

>1092_bases
ATGTTAAAAGCCGGTATTATAGGATTACCAAATGTTGGGAAATCAACTTTATTTAATGCACTTGTTGAAAATGCAAAAGC
CCAAGCTGCAAACTTTCCTTTTTGTACTATTGAACCAAATAAAGGTATCGTTTCAGTACCTGATCATAGGCTGCATCAGT
TAGCTACATTAAGTTCTAGTCAAAATGTTATTCCTACCAAGATTGAATTTGTCGATATTGCAGGTCTCGTTAAAGGTGCC
AGTAAAGGAGAGGGTTTAGGCAATAAGTTCTTATCCAATATTAGAGAAGTTGATGCAATTATTCATGTCGTAAGATGTTT
TGAAGATAGTGAAGTTATTCATGTTTCAGGAAAAATTGATCCATTAGAAGATATTGAGATTATTAATTTAGAGCTAAATC
TAGCTGATTTAACTCAGCTTCAAAAAAGGAGAGAAAGAATTAAGAAGCAAGTTAAAACATCCAAAGAAGCACAACAGGAA
GATGCTTTATTAGAAAAAATTGAGGATAAGTTACAAAAAGGTCTTTCAGTTAGATCAATATCTTTGAGCGTTGAAGAGAA
TTTAATGATTAAACAATTGGGATTCCTTACTGCAAAACCAATTATTTATGCAACTAACTTAAATGAAAATGATTTAGCTG
AAGGTAATAATCTCTCTTCAAAAGTCCAAATGTTAGCAAAAACTGAAAATACAGAATGTATAAAAATATCAGCACAAGTT
GAATCTGAATTAATTGAGTTAGGGCCTGAAGATAAAAAGGATTACCTCATAGGTTTAGGTGTAGAGGAAGGAGGATTAAA
ATCCTTAATAAAATCTACTTATAAATTATTAGGATTAAAAACTTATTTTACAACTGGAGAAAAAGAGACAAAAGCTTGGA
CAATAAAAGATGGAATGACAGCACCTCAAGCGGCAGGAGTAATACATACTGATTTTGAAAAAGGATTTATTAGAGCTCAG
ACAATTTCATATAAAAGCTTGTTAGAGTCAGGTTCTATGGCTAACGCTAAAAATAAGGGATTACTAAGAAGTGAAGGGAA
AGAATATGTAGTGAATGAGGGAGATGTTATGGAGTTCTTATTTAACGTGTGA

Upstream 100 bases:

>100_bases
TAATCGAAACGATTATGATTAACTTATCCATGATTGGTTAAGTAAACTCTATATTACAAGAAGATGATTCCTTGACTAAT
TTATCTATAAATTTTTTCAA

Downstream 100 bases:

>100_bases
TTATCAATTGCTATTAATAAAGTTTTACCCAAATTACACAGGTCTAAAAGTATTTAAAGCCTCAATAATTCTGTTCATAT
CATTGTGGTTAAGTTTAGTG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDHRLHQLATLSSSQNVIPTKIEFVDIAGLVKGA
SKGEGLGNKFLSNIREVDAIIHVVRCFEDSEVIHVSGKIDPLEDIEIINLELNLADLTQLQKRRERIKKQVKTSKEAQQE
DALLEKIEDKLQKGLSVRSISLSVEENLMIKQLGFLTAKPIIYATNLNENDLAEGNNLSSKVQMLAKTENTECIKISAQV
ESELIELGPEDKKDYLIGLGVEEGGLKSLIKSTYKLLGLKTYFTTGEKETKAWTIKDGMTAPQAAGVIHTDFEKGFIRAQ
TISYKSLLESGSMANAKNKGLLRSEGKEYVVNEGDVMEFLFNV

Sequences:

>Translated_363_residues
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDHRLHQLATLSSSQNVIPTKIEFVDIAGLVKGA
SKGEGLGNKFLSNIREVDAIIHVVRCFEDSEVIHVSGKIDPLEDIEIINLELNLADLTQLQKRRERIKKQVKTSKEAQQE
DALLEKIEDKLQKGLSVRSISLSVEENLMIKQLGFLTAKPIIYATNLNENDLAEGNNLSSKVQMLAKTENTECIKISAQV
ESELIELGPEDKKDYLIGLGVEEGGLKSLIKSTYKLLGLKTYFTTGEKETKAWTIKDGMTAPQAAGVIHTDFEKGFIRAQ
TISYKSLLESGSMANAKNKGLLRSEGKEYVVNEGDVMEFLFNV
>Mature_363_residues
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDHRLHQLATLSSSQNVIPTKIEFVDIAGLVKGA
SKGEGLGNKFLSNIREVDAIIHVVRCFEDSEVIHVSGKIDPLEDIEIINLELNLADLTQLQKRRERIKKQVKTSKEAQQE
DALLEKIEDKLQKGLSVRSISLSVEENLMIKQLGFLTAKPIIYATNLNENDLAEGNNLSSKVQMLAKTENTECIKISAQV
ESELIELGPEDKKDYLIGLGVEEGGLKSLIKSTYKLLGLKTYFTTGEKETKAWTIKDGMTAPQAAGVIHTDFEKGFIRAQ
TISYKSLLESGSMANAKNKGLLRSEGKEYVVNEGDVMEFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=40.9214092140921, Blast_Score=264, Evalue=1e-70,
Organism=Homo sapiens, GI58761502, Length=171, Percent_Identity=39.1812865497076, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=54.5454545454545, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1789574, Length=128, Percent_Identity=32.03125, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=41.2568306010929, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17552324, Length=140, Percent_Identity=32.8571428571429, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319499, Length=368, Percent_Identity=40.7608695652174, Blast_Score=252, Evalue=8e-68,
Organism=Saccharomyces cerevisiae, GI6321773, Length=378, Percent_Identity=34.1269841269841, Blast_Score=210, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6321649, Length=271, Percent_Identity=33.210332103321, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24640873, Length=369, Percent_Identity=41.7344173441734, Blast_Score=271, Evalue=7e-73,
Organism=Drosophila melanogaster, GI24640877, Length=369, Percent_Identity=41.7344173441734, Blast_Score=271, Evalue=7e-73,
Organism=Drosophila melanogaster, GI24640875, Length=369, Percent_Identity=41.7344173441734, Blast_Score=271, Evalue=7e-73,
Organism=Drosophila melanogaster, GI24640879, Length=327, Percent_Identity=39.1437308868502, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24585318, Length=138, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39904; Mature: 39904

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDHRLHQLATLSSS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCHHHHHHHHHHCCC
QNVIPTKIEFVDIAGLVKGASKGEGLGNKFLSNIREVDAIIHVVRCFEDSEVIHVSGKID
CCCCCCEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PLEDIEIINLELNLADLTQLQKRRERIKKQVKTSKEAQQEDALLEKIEDKLQKGLSVRSI
CCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
SLSVEENLMIKQLGFLTAKPIIYATNLNENDLAEGNNLSSKVQMLAKTENTECIKISAQV
EEEHHHHHHHHHHHHHEECCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEHHH
ESELIELGPEDKKDYLIGLGVEEGGLKSLIKSTYKLLGLKTYFTTGEKETKAWTIKDGMT
HHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCC
APQAAGVIHTDFEKGFIRAQTISYKSLLESGSMANAKNKGLLRSEGKEYVVNEGDVMEFL
CCCCCCCEEECCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCHHCCCCEEEECCCHHHHHH
FNV
HCC
>Mature Secondary Structure
MLKAGIIGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNKGIVSVPDHRLHQLATLSSS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCHHHHHHHHHHCCC
QNVIPTKIEFVDIAGLVKGASKGEGLGNKFLSNIREVDAIIHVVRCFEDSEVIHVSGKID
CCCCCCEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PLEDIEIINLELNLADLTQLQKRRERIKKQVKTSKEAQQEDALLEKIEDKLQKGLSVRSI
CCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
SLSVEENLMIKQLGFLTAKPIIYATNLNENDLAEGNNLSSKVQMLAKTENTECIKISAQV
EEEHHHHHHHHHHHHHEECCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEHHH
ESELIELGPEDKKDYLIGLGVEEGGLKSLIKSTYKLLGLKTYFTTGEKETKAWTIKDGMT
HHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCC
APQAAGVIHTDFEKGFIRAQTISYKSLLESGSMANAKNKGLLRSEGKEYVVNEGDVMEFL
CCCCCCCEEECCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCHHCCCCEEEECCCHHHHHH
FNV
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]