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The map label for this gene is pdxJ

Identifier: 123966431

GI number: 123966431

Start: 1058776

End: 1059492

Strand: Reverse

Name: pdxJ

Synonym: P9515_11981

Alternate gene names: 123966431

Gene position: 1059492-1058776 (Counterclockwise)

Preceding gene: 123966436

Following gene: 123966430

Centisome position: 62.17

GC content: 34.73

Gene sequence:

>717_bases
ATGGCAACATTAGGAGTAAATATAGATCATATCGCGAATGTTCGTCAGGCTAGAAGGACTGTTGAGCCAGATCCAGTTCA
ATTCGCTTTCTTGGCAGAATTAGGAGGAGCAGATTCAATAACTGTCCATTTAAGAGAAGATAGAAGGCACATACAAGATC
GAGATATATTCCTTTTAAAAGAGACTATTAAAACTAAACTAAATTTAGAAATGGCTGCTACTGAAGAGATGTTGAAAATT
TCTAAAAAATTACTTCCAGATTTCGTTACACTTGTACCAGAAAAAAGAGAGGAAGTTACAACTGAGGGAGGATTAAATGT
AAAAAATAATCAGAGATATCTTAAAGATTACGTTACCAGTTTAAAAAGTTCAAATATTGAAGTAAGTGCTTTTATCGATC
CATTAAGTGAGCAGATTAATTCTTCAGCAGAAATAGGATTCGACTTTATAGAATTACACACTGGTAAATACTCTGAATTA
AAAGGGCAAGAAAGATATGTGGAACTCCAAAAAATTATCGAATCTACCCATTATGCATTTGATCTTGGCTTAGTTGTTAA
TGCAGGGCATGGACTTAATTACCAAAATGCAGAAAAGATTGCGTCAATTAACAATATCAATGAGTTAAACATCGGGCATA
GTATTGTTGCTAGGGCTCTAGCCGTTGGCCTAGAGAGGGCTGTTAGCGAAATGAAGGCCCTTATTTCAACAAATTAA

Upstream 100 bases:

>100_bases
CAATTTCAATTTATAGTATATTAATAAATTATACGATTGTAATTTTTTATTAGCTATTATTAGTCGGTTAGTTGATTGTC
TAAACTAAATTTATAAATTT

Downstream 100 bases:

>100_bases
TTTTTTAAAAAATGACAACTTATTTTTTCGTTGCAGCAAGTGAGAAATTTTTGACAGTTGAAGAACCCCTTCACGAAATT
TTAAAAGAGAGAGCGCGTAA

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MATLGVNIDHIANVRQARRTVEPDPVQFAFLAELGGADSITVHLREDRRHIQDRDIFLLKETIKTKLNLEMAATEEMLKI
SKKLLPDFVTLVPEKREEVTTEGGLNVKNNQRYLKDYVTSLKSSNIEVSAFIDPLSEQINSSAEIGFDFIELHTGKYSEL
KGQERYVELQKIIESTHYAFDLGLVVNAGHGLNYQNAEKIASINNINELNIGHSIVARALAVGLERAVSEMKALISTN

Sequences:

>Translated_238_residues
MATLGVNIDHIANVRQARRTVEPDPVQFAFLAELGGADSITVHLREDRRHIQDRDIFLLKETIKTKLNLEMAATEEMLKI
SKKLLPDFVTLVPEKREEVTTEGGLNVKNNQRYLKDYVTSLKSSNIEVSAFIDPLSEQINSSAEIGFDFIELHTGKYSEL
KGQERYVELQKIIESTHYAFDLGLVVNAGHGLNYQNAEKIASINNINELNIGHSIVARALAVGLERAVSEMKALISTN
>Mature_237_residues
ATLGVNIDHIANVRQARRTVEPDPVQFAFLAELGGADSITVHLREDRRHIQDRDIFLLKETIKTKLNLEMAATEEMLKIS
KKLLPDFVTLVPEKREEVTTEGGLNVKNNQRYLKDYVTSLKSSNIEVSAFIDPLSEQINSSAEIGFDFIELHTGKYSELK
GQERYVELQKIIESTHYAFDLGLVVNAGHGLNYQNAEKIASINNINELNIGHSIVARALAVGLERAVSEMKALISTN

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=233, Percent_Identity=55.793991416309, Blast_Score=267, Evalue=4e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_PROM5 (A2BX94)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001011512.1
- ProteinModelPortal:   A2BX94
- SMR:   A2BX94
- STRING:   A2BX94
- GeneID:   4718961
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_11981
- eggNOG:   COG0854
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- ProtClustDB:   PRK05265
- BioCyc:   PMAR167542:P9515ORF_1252-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 26632; Mature: 26500

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: ACT_SITE 43-43 ACT_SITE 70-70 ACT_SITE 190-190 BINDING 7-7 BINDING 18-18 BINDING 45-45 BINDING 50-50 BINDING 100-100 BINDING 191-191

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLGVNIDHIANVRQARRTVEPDPVQFAFLAELGGADSITVHLREDRRHIQDRDIFLLK
CCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEEEHHHHCCCCCCHHEEH
ETIKTKLNLEMAATEEMLKISKKLLPDFVTLVPEKREEVTTEGGLNVKNNQRYLKDYVTS
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHH
LKSSNIEVSAFIDPLSEQINSSAEIGFDFIELHTGKYSELKGQERYVELQKIIESTHYAF
HHCCCEEEEHHHHHHHHHCCCCHHCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHEE
DLGLVVNAGHGLNYQNAEKIASINNINELNIGHSIVARALAVGLERAVSEMKALISTN
EEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATLGVNIDHIANVRQARRTVEPDPVQFAFLAELGGADSITVHLREDRRHIQDRDIFLLK
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEEEHHHHCCCCCCHHEEH
ETIKTKLNLEMAATEEMLKISKKLLPDFVTLVPEKREEVTTEGGLNVKNNQRYLKDYVTS
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHH
LKSSNIEVSAFIDPLSEQINSSAEIGFDFIELHTGKYSELKGQERYVELQKIIESTHYAF
HHCCCEEEEHHHHHHHHHCCCCHHCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHEE
DLGLVVNAGHGLNYQNAEKIASINNINELNIGHSIVARALAVGLERAVSEMKALISTN
EEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA