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The map label for this gene is trpD

Identifier: 123966268

GI number: 123966268

Start: 926515

End: 927543

Strand: Reverse

Name: trpD

Synonym: P9515_10351

Alternate gene names: 123966268

Gene position: 927543-926515 (Counterclockwise)

Preceding gene: 123966269

Following gene: 123966267

Centisome position: 54.43

GC content: 33.43

Gene sequence:

>1029_bases
ATGTCTAATAAAAAAAATTCAGAAATTCTAGATCAATTACTTTTTGGACATAACCTTGATGATGAAACTTCAAGAGTTTT
GATGAAAAGGTGGTTAAATAATGAAATATTAGATGTTCAAACAGGAGCCTTTTTAAGTGCATTAAGAGCTAAAGGCGCCA
CAGGTATGGAATTGTCTTGTATGGCAGAAGAGCTCTTGAACGCTTGTAAACTGCCTATTGATAGGCCGGATTTGTTTATG
GTTGATACTTGTGGTACTGGCGGTGATGGTTCAAATACATTTAATATCTCTACAGCTGTTGCCTTTGTTGCCTCTGCCTG
TGGTGTAAATATAGCAAAACATGGAAATAAAAGTGCCAGTGGAAAAGTTGGTTCTGCAGATGTTTTGTCTAATCTTGGGA
TTAATTTAAATTCTTCTTTAGATAAAGTAATTTCTGCAATAGATGATATTGGGATAACTTTTTTATTTGCTCCTATTTGG
CATAAATCATTGATTAAATTAGCTCCCTTACGAAAAGCGCTTGGTATCAGAACAATCTTTAATCAATTAGGCCCATTAGT
AAATCCATTAAGACCTAATGCACAAGTTTTAGGCGTTGCTTCTGAAGATCTTCTTACTCCTATGGCTTCTGCTTTAAATA
AAATGGGAATGGATAGAGCAATAGTTGTTCATGGCTATGGAGGCCTTGATGAGGCTTCATTAGAAGGCGATAATAAAATT
ATCTTTGTAGATAATGGTCAGCTAAAACATTCAATACTCAATGTTTCTGATTTTAATTTTCAAAATACCTCAAATAATGA
TTTGATCGTATCAAATAATCAATCTTATGAAAATATATTGGAATCTGTTTTGAAGGGTTCCGGTCAAAAAGCTCATATTG
ATGTTGTGGCTTTAAATACTTCATTAGTTCTTTGGGTGGCGGGTATTGAAAAGGATATTGAAAAAGGGTTTGAAAAAGCT
TTGTTTTCTATGAGTAAAGCAAAACCGTGGGATAAATTTTTAAGTTTGAAAGCTTATCTTGAGACATAA

Upstream 100 bases:

>100_bases
TTATGGTCAAATAACTTTAGACCTTCAAATACCACTAAAGATCTAGTCGGTTCAGGTTTTGATACCTCTAATTGAACACT
TAATCATTATTTAATAATAA

Downstream 100 bases:

>100_bases
GAAACATTTTTTTAATTAATGAATCATCCTTTTAAGAAAAATGCAAAACTTGTTTTAAGTAACGGGACTACTTTTTCTGG
TTATTCATTTGGTGCCGTCG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSNKKNSEILDQLLFGHNLDDETSRVLMKRWLNNEILDVQTGAFLSALRAKGATGMELSCMAEELLNACKLPIDRPDLFM
VDTCGTGGDGSNTFNISTAVAFVASACGVNIAKHGNKSASGKVGSADVLSNLGINLNSSLDKVISAIDDIGITFLFAPIW
HKSLIKLAPLRKALGIRTIFNQLGPLVNPLRPNAQVLGVASEDLLTPMASALNKMGMDRAIVVHGYGGLDEASLEGDNKI
IFVDNGQLKHSILNVSDFNFQNTSNNDLIVSNNQSYENILESVLKGSGQKAHIDVVALNTSLVLWVAGIEKDIEKGFEKA
LFSMSKAKPWDKFLSLKAYLET

Sequences:

>Translated_342_residues
MSNKKNSEILDQLLFGHNLDDETSRVLMKRWLNNEILDVQTGAFLSALRAKGATGMELSCMAEELLNACKLPIDRPDLFM
VDTCGTGGDGSNTFNISTAVAFVASACGVNIAKHGNKSASGKVGSADVLSNLGINLNSSLDKVISAIDDIGITFLFAPIW
HKSLIKLAPLRKALGIRTIFNQLGPLVNPLRPNAQVLGVASEDLLTPMASALNKMGMDRAIVVHGYGGLDEASLEGDNKI
IFVDNGQLKHSILNVSDFNFQNTSNNDLIVSNNQSYENILESVLKGSGQKAHIDVVALNTSLVLWVAGIEKDIEKGFEKA
LFSMSKAKPWDKFLSLKAYLET
>Mature_341_residues
SNKKNSEILDQLLFGHNLDDETSRVLMKRWLNNEILDVQTGAFLSALRAKGATGMELSCMAEELLNACKLPIDRPDLFMV
DTCGTGGDGSNTFNISTAVAFVASACGVNIAKHGNKSASGKVGSADVLSNLGINLNSSLDKVISAIDDIGITFLFAPIWH
KSLIKLAPLRKALGIRTIFNQLGPLVNPLRPNAQVLGVASEDLLTPMASALNKMGMDRAIVVHGYGGLDEASLEGDNKII
FVDNGQLKHSILNVSDFNFQNTSNNDLIVSNNQSYENILESVLKGSGQKAHIDVVALNTSLVLWVAGIEKDIEKGFEKAL
FSMSKAKPWDKFLSLKAYLET

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=331, Percent_Identity=37.7643504531722, Blast_Score=202, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6320561, Length=326, Percent_Identity=31.9018404907975, Blast_Score=113, Evalue=4e-26,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_PROM5 (A2BWT1)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001011349.1
- ProteinModelPortal:   A2BWT1
- SMR:   A2BWT1
- STRING:   A2BWT1
- GeneID:   4719100
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_10351
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   HGNKSAS
- ProtClustDB:   PRK00188
- BioCyc:   PMAR167542:P9515ORF_1082-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36909; Mature: 36778

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKKNSEILDQLLFGHNLDDETSRVLMKRWLNNEILDVQTGAFLSALRAKGATGMELSC
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECHHHHHHHHHHCCCCCCCHHH
MAEELLNACKLPIDRPDLFMVDTCGTGGDGSNTFNISTAVAFVASACGVNIAKHGNKSAS
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHCCHHHHCCCCCCC
GKVGSADVLSNLGINLNSSLDKVISAIDDIGITFLFAPIWHKSLIKLAPLRKALGIRTIF
CCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQLGPLVNPLRPNAQVLGVASEDLLTPMASALNKMGMDRAIVVHGYGGLDEASLEGDNKI
HHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEE
IFVDNGQLKHSILNVSDFNFQNTSNNDLIVSNNQSYENILESVLKGSGQKAHIDVVALNT
EEEECCCHHHHEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCEEEEEEEEECC
SLVLWVAGIEKDIEKGFEKALFSMSKAKPWDKFLSLKAYLET
EEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SNKKNSEILDQLLFGHNLDDETSRVLMKRWLNNEILDVQTGAFLSALRAKGATGMELSC
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECHHHHHHHHHHCCCCCCCHHH
MAEELLNACKLPIDRPDLFMVDTCGTGGDGSNTFNISTAVAFVASACGVNIAKHGNKSAS
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHCCHHHHCCCCCCC
GKVGSADVLSNLGINLNSSLDKVISAIDDIGITFLFAPIWHKSLIKLAPLRKALGIRTIF
CCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQLGPLVNPLRPNAQVLGVASEDLLTPMASALNKMGMDRAIVVHGYGGLDEASLEGDNKI
HHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEE
IFVDNGQLKHSILNVSDFNFQNTSNNDLIVSNNQSYENILESVLKGSGQKAHIDVVALNT
EEEECCCHHHHEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCEEEEEEEEECC
SLVLWVAGIEKDIEKGFEKALFSMSKAKPWDKFLSLKAYLET
EEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA