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The map label for this gene is carA [H]

Identifier: 123966267

GI number: 123966267

Start: 925357

End: 926496

Strand: Reverse

Name: carA [H]

Synonym: P9515_10341

Alternate gene names: 123966267

Gene position: 926496-925357 (Counterclockwise)

Preceding gene: 123966268

Following gene: 123966266

Centisome position: 54.37

GC content: 31.05

Gene sequence:

>1140_bases
ATGAATCATCCTTTTAAGAAAAATGCAAAACTTGTTTTAAGTAACGGGACTACTTTTTCTGGTTATTCATTTGGTGCCGT
CGGTACAACTCTAGGCGAAATTGTTTTTAATACTGGTATGACTGGTTATCAAGAAGTAATAACGGATCCAAGTTATTTTG
GTCAAATACTAACATTTACATATCCTGAGATAGGAAATACAGGAATTAATTTCGAAGATTCTGAATCAGACAACTGTGTT
AAAGGATTAATAGTTCGTAATTACTCAAATAATAATAGTAATTGGAGATCCCAAATAAGCCTAAATCAGTGGCTGATTGA
TAATAATATTATTGGACTTTATGGAGTTGATACGAGAGCACTTGTCAAAATTTTAAGATCTAACGGTTCGATGAATGGTC
TTATAACTTCAGAAAATAATAATTTAGATAGTTGTCTTAAGCTTATTTCTAATGCTCCGGATATGAATGGTTTAAATTTA
TCAAGAGAAGTTTCAACAAAGAATAATTATTTTTGGAAAGAGACCACTAAGACAAGTTTTGATATAAGAAAAAAGGATAT
TGGTACAAAAAATAAATTAAAAATTGTGGCAATTGATTTTGGTATCAAAAAATCAATTCTTAATAGATTAGTTTCACATG
GATGTGAGGTATTGGTATTGCCTTCACATTCTTCTTTTGAAGATGTTTTAGGCAATAATCCTGATGGGATATTTTTTTCG
AATGGTCCAGGTGATCCTTCTACTGTTCTTGATGGGATTAATTTAGCTAAATCACTAATAAATTATGGAAAAATTCCTAT
GTTTGGAATTTGTCTTGGTCATCAAATTTTTGGTTTGGCATTAGGAGGGGAAACATATAAATTACCTTTTGGACATCGTG
GTTTAAATCATCCCTGTGGGATGAATAATAATGTTGAAATAACGAGTCAGAATCATGGTTTTGCCATAGATCCAAATTCC
TTATCAAATGAAATTGTTGAAATAACTCATCTTAACCTTAATGATAAAACTGTCGCTGGATTGAAACTTAAAAATAAGCC
TATATTTAGTGTTCAATATCACCCAGAGGCAAGCCCGGGACCTCACGACTCAGATTATTTATTTGAAAATTTTGTTTCTC
TAATGTTAGAAAGATGTTGA

Upstream 100 bases:

>100_bases
GTTTGAAAAAGCTTTGTTTTCTATGAGTAAAGCAAAACCGTGGGATAAATTTTTAAGTTTGAAAGCTTATCTTGAGACAT
AAGAAACATTTTTTTAATTA

Downstream 100 bases:

>100_bases
CATGTTGATTCTTTTTGATTTGATAATTACATTTAATAAATTTATTTTCCTTGGAGGGATTAAATCATAGAAGATTTCCA
AAAGCTAACTGTTTCCTTAA

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNHPFKKNAKLVLSNGTTFSGYSFGAVGTTLGEIVFNTGMTGYQEVITDPSYFGQILTFTYPEIGNTGINFEDSESDNCV
KGLIVRNYSNNNSNWRSQISLNQWLIDNNIIGLYGVDTRALVKILRSNGSMNGLITSENNNLDSCLKLISNAPDMNGLNL
SREVSTKNNYFWKETTKTSFDIRKKDIGTKNKLKIVAIDFGIKKSILNRLVSHGCEVLVLPSHSSFEDVLGNNPDGIFFS
NGPGDPSTVLDGINLAKSLINYGKIPMFGICLGHQIFGLALGGETYKLPFGHRGLNHPCGMNNNVEITSQNHGFAIDPNS
LSNEIVEITHLNLNDKTVAGLKLKNKPIFSVQYHPEASPGPHDSDYLFENFVSLMLERC

Sequences:

>Translated_379_residues
MNHPFKKNAKLVLSNGTTFSGYSFGAVGTTLGEIVFNTGMTGYQEVITDPSYFGQILTFTYPEIGNTGINFEDSESDNCV
KGLIVRNYSNNNSNWRSQISLNQWLIDNNIIGLYGVDTRALVKILRSNGSMNGLITSENNNLDSCLKLISNAPDMNGLNL
SREVSTKNNYFWKETTKTSFDIRKKDIGTKNKLKIVAIDFGIKKSILNRLVSHGCEVLVLPSHSSFEDVLGNNPDGIFFS
NGPGDPSTVLDGINLAKSLINYGKIPMFGICLGHQIFGLALGGETYKLPFGHRGLNHPCGMNNNVEITSQNHGFAIDPNS
LSNEIVEITHLNLNDKTVAGLKLKNKPIFSVQYHPEASPGPHDSDYLFENFVSLMLERC
>Mature_379_residues
MNHPFKKNAKLVLSNGTTFSGYSFGAVGTTLGEIVFNTGMTGYQEVITDPSYFGQILTFTYPEIGNTGINFEDSESDNCV
KGLIVRNYSNNNSNWRSQISLNQWLIDNNIIGLYGVDTRALVKILRSNGSMNGLITSENNNLDSCLKLISNAPDMNGLNL
SREVSTKNNYFWKETTKTSFDIRKKDIGTKNKLKIVAIDFGIKKSILNRLVSHGCEVLVLPSHSSFEDVLGNNPDGIFFS
NGPGDPSTVLDGINLAKSLINYGKIPMFGICLGHQIFGLALGGETYKLPFGHRGLNHPCGMNNNVEITSQNHGFAIDPNS
LSNEIVEITHLNLNDKTVAGLKLKNKPIFSVQYHPEASPGPHDSDYLFENFVSLMLERC

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI21361331, Length=383, Percent_Identity=39.686684073107, Blast_Score=244, Evalue=9e-65,
Organism=Homo sapiens, GI169790915, Length=383, Percent_Identity=39.686684073107, Blast_Score=244, Evalue=9e-65,
Organism=Homo sapiens, GI18105007, Length=382, Percent_Identity=37.9581151832461, Blast_Score=231, Evalue=1e-60,
Organism=Escherichia coli, GI1786215, Length=378, Percent_Identity=44.973544973545, Blast_Score=323, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI193204318, Length=378, Percent_Identity=38.3597883597884, Blast_Score=237, Evalue=8e-63,
Organism=Saccharomyces cerevisiae, GI6322331, Length=391, Percent_Identity=38.1074168797954, Blast_Score=245, Evalue=7e-66,
Organism=Saccharomyces cerevisiae, GI6324878, Length=380, Percent_Identity=38.9473684210526, Blast_Score=243, Evalue=5e-65,
Organism=Drosophila melanogaster, GI45555749, Length=391, Percent_Identity=36.5728900255754, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24642586, Length=391, Percent_Identity=36.5728900255754, Blast_Score=229, Evalue=3e-60,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 41742; Mature: 41742

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHPFKKNAKLVLSNGTTFSGYSFGAVGTTLGEIVFNTGMTGYQEVITDPSYFGQILTFT
CCCCCCCCCEEEEECCCEECCEECCHHHHHHHHHHHHCCCCHHHHHHCCHHHHCEEEEEE
YPEIGNTGINFEDSESDNCVKGLIVRNYSNNNSNWRSQISLNQWLIDNNIIGLYGVDTRA
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEEEEEECCCEEEEEECCHHH
LVKILRSNGSMNGLITSENNNLDSCLKLISNAPDMNGLNLSREVSTKNNYFWKETTKTSF
HHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEECCCCCC
DIRKKDIGTKNKLKIVAIDFGIKKSILNRLVSHGCEVLVLPSHSSFEDVLGNNPDGIFFS
EEHHHCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCEEEEC
NGPGDPSTVLDGINLAKSLINYGKIPMFGICLGHQIFGLALGGETYKLPFGHRGLNHPCG
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHEEEEEECCCEEECCCCCCCCCCCCC
MNNNVEITSQNHGFAIDPNSLSNEIVEITHLNLNDKTVAGLKLKNKPIFSVQYHPEASPG
CCCCEEEEECCCCEEECCCCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEECCCCCCC
PHDSDYLFENFVSLMLERC
CCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHPFKKNAKLVLSNGTTFSGYSFGAVGTTLGEIVFNTGMTGYQEVITDPSYFGQILTFT
CCCCCCCCCEEEEECCCEECCEECCHHHHHHHHHHHHCCCCHHHHHHCCHHHHCEEEEEE
YPEIGNTGINFEDSESDNCVKGLIVRNYSNNNSNWRSQISLNQWLIDNNIIGLYGVDTRA
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEEEEEECCCEEEEEECCHHH
LVKILRSNGSMNGLITSENNNLDSCLKLISNAPDMNGLNLSREVSTKNNYFWKETTKTSF
HHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEECCCCCC
DIRKKDIGTKNKLKIVAIDFGIKKSILNRLVSHGCEVLVLPSHSSFEDVLGNNPDGIFFS
EEHHHCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCEEEEC
NGPGDPSTVLDGINLAKSLINYGKIPMFGICLGHQIFGLALGGETYKLPFGHRGLNHPCG
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHEEEEEECCCEEECCCCCCCCCCCCC
MNNNVEITSQNHGFAIDPNSLSNEIVEITHLNLNDKTVAGLKLKNKPIFSVQYHPEASPG
CCCCEEEEECCCCEEECCCCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEECCCCCCC
PHDSDYLFENFVSLMLERC
CCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA