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The map label for this gene is cumB [H]

Identifier: 123966234

GI number: 123966234

Start: 895748

End: 896245

Strand: Direct

Name: cumB [H]

Synonym: P9515_10011

Alternate gene names: 123966234

Gene position: 895748-896245 (Clockwise)

Preceding gene: 123966232

Following gene: 123966236

Centisome position: 52.56

GC content: 32.93

Gene sequence:

>498_bases
ATGAATCATGATTTTGAAATTCAACATAGAGAAATTACTAATATAGATTATATTAAATGGATGAGATCTATTTTAAGAAG
ATCAGATGAAGTCGGGAAAGTGGAATTACCAATAACGGCATTTATAATAGATGAGAGAGGAAGATGTATTGGAAGAGGAA
GTAATAAAAGAGAAACTAATAATGATCCTTTAGGTCATGCTGAACTAATAGCACTTAGGCAAGCGTCTTGGATTAAAAAT
GATTGGCGATTTAATGAATGCAGCATTATTGTTAATTTAGAACCTTGTACAATGTGTGCGGCAGCGTTAGTTCAAGCAAG
AATGGGGAATGTTATATATGGTGCTGAAGATCATAAGAGAGGTGGTTTCGGAGGTACTATTGATCTATCTAAACACGAAA
GCGCTCATCATAAAATGAATGTCATACGGGGAATATTAGATAAGGATTGCGAAAATAGAATAAAGATTTGGTTTAAAAAG
TTGAGGAATCAAAAATAG

Upstream 100 bases:

>100_bases
AATAGTTTTTCTTTTTTATTAATTGAATCTACAGTCATTCTATAAAAAATTTATTTAAGTAATTTATGATATTTATAAAT
GGGAATTACTACTAATAATA

Downstream 100 bases:

>100_bases
TAAATTTCTTTAATTCAGTATCGAATAAATTTAATAATCGATCAACATTTTCATCACTTGAATTAAATCCCATTAAACCA
ATACGCCATACTTTGCCTGA

Product: putative cytidine/deoxycytidylate deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MNHDFEIQHREITNIDYIKWMRSILRRSDEVGKVELPITAFIIDERGRCIGRGSNKRETNNDPLGHAELIALRQASWIKN
DWRFNECSIIVNLEPCTMCAAALVQARMGNVIYGAEDHKRGGFGGTIDLSKHESAHHKMNVIRGILDKDCENRIKIWFKK
LRNQK

Sequences:

>Translated_165_residues
MNHDFEIQHREITNIDYIKWMRSILRRSDEVGKVELPITAFIIDERGRCIGRGSNKRETNNDPLGHAELIALRQASWIKN
DWRFNECSIIVNLEPCTMCAAALVQARMGNVIYGAEDHKRGGFGGTIDLSKHESAHHKMNVIRGILDKDCENRIKIWFKK
LRNQK
>Mature_165_residues
MNHDFEIQHREITNIDYIKWMRSILRRSDEVGKVELPITAFIIDERGRCIGRGSNKRETNNDPLGHAELIALRQASWIKN
DWRFNECSIIVNLEPCTMCAAALVQARMGNVIYGAEDHKRGGFGGTIDLSKHESAHHKMNVIRGILDKDCENRIKIWFKK
LRNQK

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=146, Percent_Identity=33.5616438356164, Blast_Score=103, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19098; Mature: 19098

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHDFEIQHREITNIDYIKWMRSILRRSDEVGKVELPITAFIIDERGRCIGRGSNKRETN
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCEEEEEECCCCCEECCCCCCCCCC
NDPLGHAELIALRQASWIKNDWRFNECSIIVNLEPCTMCAAALVQARMGNVIYGAEDHKR
CCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCEEECCCCCCC
GGFGGTIDLSKHESAHHKMNVIRGILDKDCENRIKIWFKKLRNQK
CCCCCEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNHDFEIQHREITNIDYIKWMRSILRRSDEVGKVELPITAFIIDERGRCIGRGSNKRETN
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCEEEEEECCCCCEECCCCCCCCCC
NDPLGHAELIALRQASWIKNDWRFNECSIIVNLEPCTMCAAALVQARMGNVIYGAEDHKR
CCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCEEECCCCCCC
GGFGGTIDLSKHESAHHKMNVIRGILDKDCENRIKIWFKKLRNQK
CCCCCEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]