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The map label for this gene is lspA [H]

Identifier: 123966231

GI number: 123966231

Start: 892222

End: 892680

Strand: Direct

Name: lspA [H]

Synonym: P9515_09981

Alternate gene names: 123966231

Gene position: 892222-892680 (Clockwise)

Preceding gene: 123966230

Following gene: 123966232

Centisome position: 52.36

GC content: 18.52

Gene sequence:

>459_bases
ATGATAAATATTATATATAATAGATTTTATTTTATTTTATTAAGTACATTAGTTTTTCTGTCTGATCAATACGCAAAAAT
TTTTGTTAGTACAAATTTTAAATCATTAATAAATAAAAGCTTTTTAATTTTTAGTCTTGATTATGTAAAAAATTTCGGAG
CTGCTTTCAATCTATTTAGTGGTAATAGGATTTTCTTATCACTTATAAGCATAATAATTACTATACTACTTATATATTTT
ATTTTAAATAAAAAAAATATTAGTAATTTAGAATTACTAAGTTTTAGCTTTATATTAGGCGGTACATTAGGAAATGGAAT
AGATAGAATAAATAAGGGATATGTTATAGACTATATAAATTTAAACTTTATAAATTTTCCTGTATTTAATATTGCAGATA
TTTCAATTAATATTGGCCTCATATTAATTATATATAGTTTTATTAAATTCAAAAGATAA

Upstream 100 bases:

>100_bases
CAAAATACTCATTTGGAAAGTTTTTTTACCACTTACTAATGCTAATACCGATAACTTTATTAAGTAAATTTCTTAATATT
AAATATAGAAATAAAAAATA

Downstream 100 bases:

>100_bases
TAATGTATAAGTTTATATTTAAATACTATAAATACTTATTTATTTTAATATTTATTTATTTTCTATTATCCTTACTTAGA
AATATTTTTAATCTATATTT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MINIIYNRFYFILLSTLVFLSDQYAKIFVSTNFKSLINKSFLIFSLDYVKNFGAAFNLFSGNRIFLSLISIIITILLIYF
ILNKKNISNLELLSFSFILGGTLGNGIDRINKGYVIDYINLNFINFPVFNIADISINIGLILIIYSFIKFKR

Sequences:

>Translated_152_residues
MINIIYNRFYFILLSTLVFLSDQYAKIFVSTNFKSLINKSFLIFSLDYVKNFGAAFNLFSGNRIFLSLISIIITILLIYF
ILNKKNISNLELLSFSFILGGTLGNGIDRINKGYVIDYINLNFINFPVFNIADISINIGLILIIYSFIKFKR
>Mature_152_residues
MINIIYNRFYFILLSTLVFLSDQYAKIFVSTNFKSLINKSFLIFSLDYVKNFGAAFNLFSGNRIFLSLISIIITILLIYF
ILNKKNISNLELLSFSFILGGTLGNGIDRINKGYVIDYINLNFINFPVFNIADISINIGLILIIYSFIKFKR

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=105, Percent_Identity=34.2857142857143, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17530; Mature: 17530

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINIIYNRFYFILLSTLVFLSDQYAKIFVSTNFKSLINKSFLIFSLDYVKNFGAAFNLFS
CEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCEEEEHHHHHCCCCEEECCC
GNRIFLSLISIIITILLIYFILNKKNISNLELLSFSFILGGTLGNGIDRINKGYVIDYIN
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHCCCCEEEEEEE
LNFINFPVFNIADISINIGLILIIYSFIKFKR
EEEEECCCEEEEEEEECHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINIIYNRFYFILLSTLVFLSDQYAKIFVSTNFKSLINKSFLIFSLDYVKNFGAAFNLFS
CEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCEEEEHHHHHCCCCEEECCC
GNRIFLSLISIIITILLIYFILNKKNISNLELLSFSFILGGTLGNGIDRINKGYVIDYIN
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHCCCCEEEEEEE
LNFINFPVFNIADISINIGLILIIYSFIKFKR
EEEEECCCEEEEEEEECHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]