Click here to switch to the map view.

The map label for this gene is coaD

Identifier: 123966199

GI number: 123966199

Start: 861021

End: 861500

Strand: Direct

Name: coaD

Synonym: P9515_09661

Alternate gene names: 123966199

Gene position: 861021-861500 (Clockwise)

Preceding gene: 123966194

Following gene: 123966204

Centisome position: 50.52

GC content: 30.21

Gene sequence:

>480_bases
ATGAAAATACTTTACCCAGGTACATTTGATCCTTTAACAAATGGACATCTAGATTTAATACAAAGAGCAGAGAAATTATT
TGGAAATGTAGTAGTAGCGGTTTTAGAAAATACGAGTAAGAAACCTACTTTTGAACTCAGTCGGCGACTCATACAAATAA
ATAACGCAATATCTCACCTTTCAAAAATAAGTGTAATTTCTTACGAAGGTCTTACCGTAGATTGTGCTCAGGATGTTAAC
GCTAACCTTATTTTAAGAGGATTAAGAGCCATGAGTGATTTTGAATATGAACTTCAAATAGCACATACAAATAAATCTCT
TAATAGTGAAATAGAAACTATTTTTTTATCTACTAATACAAACTTTAGTTTCTTAAGTAGTTCTTTGGTTAAAGAAGTTG
CTAAATTTGGAGGAGAAATAAATCATATGGTTCCAGAAGCTGTGGAAAGAGATCTAAAGGAATATTTCAAAAAAAATTAA

Upstream 100 bases:

>100_bases
TTTCTTAATAAGATTTTTTTTGCTTCAAGATTTAATGTCATAATTAATTTAATTAATAATTTTATTTTAACTAAATATCC
TTTCTAATCATAATCAAGTT

Downstream 100 bases:

>100_bases
AAACATCCTTCTAATTTATAAATATTTTTTAATAAGTTAAATGTAGTATCTCTATCGATGTTTTCTGAATTTTGAATAAT
ACTTACAACAAAAGATTTGT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKILYPGTFDPLTNGHLDLIQRAEKLFGNVVVAVLENTSKKPTFELSRRLIQINNAISHLSKISVISYEGLTVDCAQDVN
ANLILRGLRAMSDFEYELQIAHTNKSLNSEIETIFLSTNTNFSFLSSSLVKEVAKFGGEINHMVPEAVERDLKEYFKKN

Sequences:

>Translated_159_residues
MKILYPGTFDPLTNGHLDLIQRAEKLFGNVVVAVLENTSKKPTFELSRRLIQINNAISHLSKISVISYEGLTVDCAQDVN
ANLILRGLRAMSDFEYELQIAHTNKSLNSEIETIFLSTNTNFSFLSSSLVKEVAKFGGEINHMVPEAVERDLKEYFKKN
>Mature_159_residues
MKILYPGTFDPLTNGHLDLIQRAEKLFGNVVVAVLENTSKKPTFELSRRLIQINNAISHLSKISVISYEGLTVDCAQDVN
ANLILRGLRAMSDFEYELQIAHTNKSLNSEIETIFLSTNTNFSFLSSSLVKEVAKFGGEINHMVPEAVERDLKEYFKKN

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=151, Percent_Identity=44.3708609271523, Blast_Score=159, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_PROM5 (A2BWL2)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001011280.1
- ProteinModelPortal:   A2BWL2
- SMR:   A2BWL2
- STRING:   A2BWL2
- GeneID:   4719199
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_09661
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   PMAR167542:P9515ORF_1014-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17908; Mature: 17908

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILYPGTFDPLTNGHLDLIQRAEKLFGNVVVAVLENTSKKPTFELSRRLIQINNAISHL
CEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SKISVISYEGLTVDCAQDVNANLILRGLRAMSDFEYELQIAHTNKSLNSEIETIFLSTNT
HHHHEEEECCEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCC
NFSFLSSSLVKEVAKFGGEINHMVPEAVERDLKEYFKKN
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKILYPGTFDPLTNGHLDLIQRAEKLFGNVVVAVLENTSKKPTFELSRRLIQINNAISHL
CEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SKISVISYEGLTVDCAQDVNANLILRGLRAMSDFEYELQIAHTNKSLNSEIETIFLSTNT
HHHHEEEECCEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCC
NFSFLSSSLVKEVAKFGGEINHMVPEAVERDLKEYFKKN
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA