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The map label for this gene is sds [H]

Identifier: 123965918

GI number: 123965918

Start: 619714

End: 620685

Strand: Direct

Name: sds [H]

Synonym: P9515_06831

Alternate gene names: 123965918

Gene position: 619714-620685 (Clockwise)

Preceding gene: 123965917

Following gene: 123965919

Centisome position: 36.36

GC content: 32.61

Gene sequence:

>972_bases
ATGAATACAGTAACAGAACTTCTACAGCCAGTTGAAAATGATCTTGATGATCTTATTCTCGAACTGAAAAATTTGATAGG
TGCAGGTCATCCAATCCTTCAAGCTGCAGCGGAACATTTATTTAGTGCAGGAGGAAAAAGATTAAGGCCTGGGATAGTTT
TATTGATTTCAAAGGCTATTTCTCGAGATTTTAATTTAACCACTAAACATAAAAGACTTGCAGAGATTACTGAAATGATT
CATACAGCATCATTAGTTCATGATGATGTAGTTGATGAAGCATCCACAAGAAGAGGTGTTGATACTGTTCATAGTAGATT
TAACACTAGGGTAGCTGTTCTTGCTGGGGATTTTTTATTTGCTCAAGCTAGTTGGCATTTGGCAAACTTGGATAATGTAA
AAGTAGTTAAATTACTTAGTAGAGTAATAATGGATTTAGCAGAAGGTGAAATAAAGCAAAATCTTAATAGATTTGATTCT
GGACAAACTTTTTCGAAATATATTAATAAGAGTTATTGTAAAACAGCCTCTTTAATTGCTAATAGTACTAAAGCTGCGGG
TGTCTTGAGTAATTTAGAAGATGATAAATTAAATTGTCTATATGAATTTGGTAAGAATATTGGATTAGCTTTTCAAGTGG
TTGATGATATTCTCGATTTTACAGGAAACGATAAACAATTAGGAAAACCAGCTGTAAGTGATCTTGCTAGTGGTTACCTT
ACTGCACCTGTTTTATATGCTCTAGAAGAAAATAAAAATTTATCTGTTTTGATAAATAGAGAACTTGTAGAAAAGGAAGA
CTTAAATAATGCTTTAAATATTGTTATGAACTCTCAAGCTATTCAGCGTTCTAGAAAATTAGCCGAAGATTTTGCCGTTC
TCTCGAAGGAAGCTATATTATGGCTTCCTAATTCAGAATATAAAAGAGCTTTACTAGCTTTACCAGAATTCGTTCTGAGT
CGTATTTCTTAG

Upstream 100 bases:

>100_bases
TTCTAAAAAAGTAAAATATTGGTTAGAAATTAATAAAGAAATTAGGCTAGTTAACCTCCGAAGCAATGCTTGATTCTTTA
GTATATTAAGGAGGTCAATT

Downstream 100 bases:

>100_bases
ATTTATCAAAAAATAAATTTTTGTAGTTTAAAATACATTAAATTTCTTTCAAATTTATAATGTATTTGACTAAATAAATT
GTGACTAGATTCATCTAATG

Product: polyprenyl synthetase; solanesyl diphosphate synthase (sds)

Products: diphosphate; all-trans-nonaprenyl diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MNTVTELLQPVENDLDDLILELKNLIGAGHPILQAAAEHLFSAGGKRLRPGIVLLISKAISRDFNLTTKHKRLAEITEMI
HTASLVHDDVVDEASTRRGVDTVHSRFNTRVAVLAGDFLFAQASWHLANLDNVKVVKLLSRVIMDLAEGEIKQNLNRFDS
GQTFSKYINKSYCKTASLIANSTKAAGVLSNLEDDKLNCLYEFGKNIGLAFQVVDDILDFTGNDKQLGKPAVSDLASGYL
TAPVLYALEENKNLSVLINRELVEKEDLNNALNIVMNSQAIQRSRKLAEDFAVLSKEAILWLPNSEYKRALLALPEFVLS
RIS

Sequences:

>Translated_323_residues
MNTVTELLQPVENDLDDLILELKNLIGAGHPILQAAAEHLFSAGGKRLRPGIVLLISKAISRDFNLTTKHKRLAEITEMI
HTASLVHDDVVDEASTRRGVDTVHSRFNTRVAVLAGDFLFAQASWHLANLDNVKVVKLLSRVIMDLAEGEIKQNLNRFDS
GQTFSKYINKSYCKTASLIANSTKAAGVLSNLEDDKLNCLYEFGKNIGLAFQVVDDILDFTGNDKQLGKPAVSDLASGYL
TAPVLYALEENKNLSVLINRELVEKEDLNNALNIVMNSQAIQRSRKLAEDFAVLSKEAILWLPNSEYKRALLALPEFVLS
RIS
>Mature_323_residues
MNTVTELLQPVENDLDDLILELKNLIGAGHPILQAAAEHLFSAGGKRLRPGIVLLISKAISRDFNLTTKHKRLAEITEMI
HTASLVHDDVVDEASTRRGVDTVHSRFNTRVAVLAGDFLFAQASWHLANLDNVKVVKLLSRVIMDLAEGEIKQNLNRFDS
GQTFSKYINKSYCKTASLIANSTKAAGVLSNLEDDKLNCLYEFGKNIGLAFQVVDDILDFTGNDKQLGKPAVSDLASGYL
TAPVLYALEENKNLSVLINRELVEKEDLNNALNIVMNSQAIQRSRKLAEDFAVLSKEAILWLPNSEYKRALLALPEFVLS
RIS

Specific function: Possible role in synthesis of the nonaprenyl side chain of plastoquinone or in synthesis of other prenyl chains such as undekaprenyl pyrophosphate [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=293, Percent_Identity=39.5904436860068, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI169808399, Length=229, Percent_Identity=30.1310043668122, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4758430, Length=222, Percent_Identity=24.7747747747748, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI83700220, Length=222, Percent_Identity=24.7747747747748, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789578, Length=287, Percent_Identity=32.404181184669, Blast_Score=170, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17505681, Length=294, Percent_Identity=35.0340136054422, Blast_Score=183, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6319475, Length=326, Percent_Identity=34.9693251533742, Blast_Score=184, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24651612, Length=312, Percent_Identity=36.8589743589744, Blast_Score=214, Evalue=5e-56,
Organism=Drosophila melanogaster, GI21356309, Length=355, Percent_Identity=25.0704225352113, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR014120
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: 2.5.1.11

Molecular weight: Translated: 35756; Mature: 35756

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVTELLQPVENDLDDLILELKNLIGAGHPILQAAAEHLFSAGGKRLRPGIVLLISKAI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
SRDFNLTTKHKRLAEITEMIHTASLVHDDVVDEASTRRGVDTVHSRFNTRVAVLAGDFLF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEEECHHHH
AQASWHLANLDNVKVVKLLSRVIMDLAEGEIKQNLNRFDSGQTFSKYINKSYCKTASLIA
HHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
NSTKAAGVLSNLEDDKLNCLYEFGKNIGLAFQVVDDILDFTGNDKQLGKPAVSDLASGYL
CCHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCHH
TAPVLYALEENKNLSVLINRELVEKEDLNNALNIVMNSQAIQRSRKLAEDFAVLSKEAIL
HHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEE
WLPNSEYKRALLALPEFVLSRIS
ECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTVTELLQPVENDLDDLILELKNLIGAGHPILQAAAEHLFSAGGKRLRPGIVLLISKAI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
SRDFNLTTKHKRLAEITEMIHTASLVHDDVVDEASTRRGVDTVHSRFNTRVAVLAGDFLF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEEEEECHHHH
AQASWHLANLDNVKVVKLLSRVIMDLAEGEIKQNLNRFDSGQTFSKYINKSYCKTASLIA
HHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
NSTKAAGVLSNLEDDKLNCLYEFGKNIGLAFQVVDDILDFTGNDKQLGKPAVSDLASGYL
CCHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCHH
TAPVLYALEENKNLSVLINRELVEKEDLNNALNIVMNSQAIQRSRKLAEDFAVLSKEAIL
HHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEE
WLPNSEYKRALLALPEFVLSRIS
ECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: all-trans-octaprenyl diphosphate; isopentenyl diphosphate

Specific reaction: all-trans-octaprenyl diphosphate + isopentenyl diphosphate = diphosphate + all-trans-nonaprenyl diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]