Click here to switch to the map view.

The map label for this gene is trpF [H]

Identifier: 123965836

GI number: 123965836

Start: 538640

End: 539293

Strand: Reverse

Name: trpF [H]

Synonym: P9515_06011

Alternate gene names: 123965836

Gene position: 539293-538640 (Counterclockwise)

Preceding gene: 123965838

Following gene: 123965829

Centisome position: 31.65

GC content: 28.44

Gene sequence:

>654_bases
ATGCCTAAGACCAAAACTTTAGTTAAAATTTGCGGAATAACATCTATTGATCAAGCTGTTCAAATAGCTGAATTAGGAAC
TAATGCGATAGGTATTATTTCTGTTAATGAATCTCCAAGATATATTTCCCCAGAAAAAAAAAAAGAAATCTTCAAAACTT
TAAAAATTTTATATCCAAATATTGAGAGAGTTTCGGTAGTAAAGAATAGCCCTATTGAATCAATTATTAAAAATTTCTTA
GGAGAGCCAAACGAAACTATAATTCAACTTCATGGAGATGAGGATGTCGATTACTGTCAACAATTAAGGCAAAAAATTCC
GAACATTGGTATTTGGAAAGCGTTTAGGATAAAAAATAAAAAAGATATTGAAAAAATCAAAATCTATGAAAAATTTGTAG
ACGCAATACTTTTAGATTCATGGAATAAAGAAACATATGGAGGTTCTGGTAAGAGAATAGAAAAAAGTTATTTAGAGGAA
TTAAGTTTTAGTAAACCATGGTGGCTTGCTGGAGGTGTCTCTAAAGAATGGATATATGAGATTTTAAAAAAGATAAAACC
AAATGGGATTGATATTTCAAGTAGCGTCGAGATCTCTCCAGGAATAAAAGATTTAGAAAAAACAAAAAATATAATTAGAG
AAATAAATAAATAA

Upstream 100 bases:

>100_bases
TTTAAAGGGGATTCCCCATATTTTAAAAATTTGCAAACTTCTCAAAAAAGATCTCCTTTATATTTACAAATAATATTAAT
TCTACATATATGATAAAGAT

Downstream 100 bases:

>100_bases
TCTATTTCTTAAATAATTAATATCAAACAACTATAAAAAATAACTTCTCGCTAATCTAATAACAAGATAACGCATTTGGT
TGTTGTTTAACTAACTCAAA

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MPKTKTLVKICGITSIDQAVQIAELGTNAIGIISVNESPRYISPEKKKEIFKTLKILYPNIERVSVVKNSPIESIIKNFL
GEPNETIIQLHGDEDVDYCQQLRQKIPNIGIWKAFRIKNKKDIEKIKIYEKFVDAILLDSWNKETYGGSGKRIEKSYLEE
LSFSKPWWLAGGVSKEWIYEILKKIKPNGIDISSSVEISPGIKDLEKTKNIIREINK

Sequences:

>Translated_217_residues
MPKTKTLVKICGITSIDQAVQIAELGTNAIGIISVNESPRYISPEKKKEIFKTLKILYPNIERVSVVKNSPIESIIKNFL
GEPNETIIQLHGDEDVDYCQQLRQKIPNIGIWKAFRIKNKKDIEKIKIYEKFVDAILLDSWNKETYGGSGKRIEKSYLEE
LSFSKPWWLAGGVSKEWIYEILKKIKPNGIDISSSVEISPGIKDLEKTKNIIREINK
>Mature_216_residues
PKTKTLVKICGITSIDQAVQIAELGTNAIGIISVNESPRYISPEKKKEIFKTLKILYPNIERVSVVKNSPIESIIKNFLG
EPNETIIQLHGDEDVDYCQQLRQKIPNIGIWKAFRIKNKKDIEKIKIYEKFVDAILLDSWNKETYGGSGKRIEKSYLEEL
SFSKPWWLAGGVSKEWIYEILKKIKPNGIDISSSVEISPGIKDLEKTKNIIREINK

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=208, Percent_Identity=28.3653846153846, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 24805; Mature: 24674

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTKTLVKICGITSIDQAVQIAELGTNAIGIISVNESPRYISPEKKKEIFKTLKILYPN
CCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
IERVSVVKNSPIESIIKNFLGEPNETIIQLHGDEDVDYCQQLRQKIPNIGIWKAFRIKNK
CHHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCHHEECCCH
KDIEKIKIYEKFVDAILLDSWNKETYGGSGKRIEKSYLEELSFSKPWWLAGGVSKEWIYE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHH
ILKKIKPNGIDISSSVEISPGIKDLEKTKNIIREINK
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKTKTLVKICGITSIDQAVQIAELGTNAIGIISVNESPRYISPEKKKEIFKTLKILYPN
CCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
IERVSVVKNSPIESIIKNFLGEPNETIIQLHGDEDVDYCQQLRQKIPNIGIWKAFRIKNK
CHHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCHHEECCCH
KDIEKIKIYEKFVDAILLDSWNKETYGGSGKRIEKSYLEELSFSKPWWLAGGVSKEWIYE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHH
ILKKIKPNGIDISSSVEISPGIKDLEKTKNIIREINK
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA