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The map label for this gene is cyoB [H]

Identifier: 123965742

GI number: 123965742

Start: 454025

End: 455644

Strand: Reverse

Name: cyoB [H]

Synonym: P9515_05071

Alternate gene names: 123965742

Gene position: 455644-454025 (Counterclockwise)

Preceding gene: 123965743

Following gene: 123965741

Centisome position: 26.74

GC content: 35.93

Gene sequence:

>1620_bases
ATGACAATATTAATTGATTCACAAGATTCCAATAACAAGAGTCTTCAACCTAAAGGTTGGCTTAGATATTTTAGCTTTAG
TCTTGATCATAAAGTAATAGGTATCCAATATTTAGTATGTGGGTTTCTTTTTTATTTAATTGGAGGAACTTTGGCAAGTG
CTATAAGAATTGAATTAACAAGTCCAATGTCGGACTTTATGCCTAGAGATATATATAACCAAGTTTTAACATTACATGGA
ACAATAATGATTTTCTTGTGGATTGTACCTGTAGTAAATGGTGCATTTGGGAATTATTTAATTCCTTTTTATGTTGGAGC
AAGAGATATGGCATTCCCAAGACTGAATGCTGTAGCTTTTTGGCTAATACCCCCTTCCGGTTTAATGTTAGTGGCTAGTT
ATTTTGTTGAAGGAGCTGCACAGGCAGGATGGACTGCGTATCCTCCTTTGAGTATAACAACCCCACAATCGGGACAAATA
ATTTGGATAATGAGTGTTTTATTGCTCGGAGGCAGCTCAATTTTTGGAGGGATAAATTTCATTGCAACAATTATCAAATT
AAGAAGACCAGGATTAAAGCTTATGCAACTACCTATGTATTGTTGGGCGATGTTAGGGACAAGTTTATTAGTAGTTTTGT
CAACTCCAGTTTTAGCTGGAACATTAATATTGCTTAGCTTTGATATTGTTGCTCATACCGGTTTCTTTAACCCTGTTTTG
GGTGGGAACGTAGTCGTTTATCAACATTTATTCTGGTTTTATTCTCACCCAGCTGTTTACATAATGGTACTTCCTGCTTT
CGGATTGGTTAGTGAAATCCTTCCAGTACATTCAAGGAAGCCACTTTTTGGATACACCACAATGGTTTTTTCAATAATGG
GAATAGTTGTTCTTGGTCTAGTTGTTTGGGCTCATCATATGTTTACAAGTGGAACCCCACCTTGGATGAGATTATTCTTT
ACCATCGCGACAGCGTTTATAGCAGTTCCAACTGGAATTAAATTTTTTAATTGGGTTGCAACATTGTGGGGCGGGAAAAT
ATCTATCAATAGTGCAATGTTATTTTCATGTGGATTTATAATTAATTTTGTATTTGGAGGTATTACGGGAGTTGCTCTAG
CTCAAGTACCTTTTGATATTCATGTCCATGATACATATTTTGTTGTAGCTCACTTCCATTACATCGTTTACGGAGGGACC
GTTTTTATTATCTTCTCATCCATATACCATTGGTTCCCAAAGGTGACAGGTAAGTTAATGAATGAAAAACTAGGGATATT
ACATTTTGCCATAACTTTTATTGGATTTAACTTATGTTTTGCTCCTCAACATTGGCTTGGTCTTAATGGAATGCCTAGAA
GGGTGGCAGAATATGATCCTCAATTTCAATTTGTTAATCAAATTAGTAGCCTTGGTGCTCTCTTAATGGCTATTAGTACT
ATCCCTTTTTTGATCAATATATATGCAAGTATTAAAAATGGTAAGGATTCTGGGGATAATCCTTGGGATGCTTTAACTCC
TGAATGGTTAACAACCTCTCCTCCACCCGTTGAGAATTGGGAAGGAGAAGCACCTTTAGTAGAAGAACCTTATGGTTATG
GAAAACCAATCTCTAAATAA

Upstream 100 bases:

>100_bases
GTGGTCCTTATCACGGAGGCATGAGAGCATCAATAATAGTTGAAGAAGAATCTGATTACAAAGATTGGTTTAACAAAAAT
ACAAAAACTGAGGTTAGTTT

Downstream 100 bases:

>100_bases
AATCAATCAAAAAGTATGACAACTCTAGATAGTTCAAAAGAAATTAAAAAAAATGAGAGTGAGCTAAGGGAACATCATGA
AGACTTCAGGATGTTTGGAT

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MTILIDSQDSNNKSLQPKGWLRYFSFSLDHKVIGIQYLVCGFLFYLIGGTLASAIRIELTSPMSDFMPRDIYNQVLTLHG
TIMIFLWIVPVVNGAFGNYLIPFYVGARDMAFPRLNAVAFWLIPPSGLMLVASYFVEGAAQAGWTAYPPLSITTPQSGQI
IWIMSVLLLGGSSIFGGINFIATIIKLRRPGLKLMQLPMYCWAMLGTSLLVVLSTPVLAGTLILLSFDIVAHTGFFNPVL
GGNVVVYQHLFWFYSHPAVYIMVLPAFGLVSEILPVHSRKPLFGYTTMVFSIMGIVVLGLVVWAHHMFTSGTPPWMRLFF
TIATAFIAVPTGIKFFNWVATLWGGKISINSAMLFSCGFIINFVFGGITGVALAQVPFDIHVHDTYFVVAHFHYIVYGGT
VFIIFSSIYHWFPKVTGKLMNEKLGILHFAITFIGFNLCFAPQHWLGLNGMPRRVAEYDPQFQFVNQISSLGALLMAIST
IPFLINIYASIKNGKDSGDNPWDALTPEWLTTSPPPVENWEGEAPLVEEPYGYGKPISK

Sequences:

>Translated_539_residues
MTILIDSQDSNNKSLQPKGWLRYFSFSLDHKVIGIQYLVCGFLFYLIGGTLASAIRIELTSPMSDFMPRDIYNQVLTLHG
TIMIFLWIVPVVNGAFGNYLIPFYVGARDMAFPRLNAVAFWLIPPSGLMLVASYFVEGAAQAGWTAYPPLSITTPQSGQI
IWIMSVLLLGGSSIFGGINFIATIIKLRRPGLKLMQLPMYCWAMLGTSLLVVLSTPVLAGTLILLSFDIVAHTGFFNPVL
GGNVVVYQHLFWFYSHPAVYIMVLPAFGLVSEILPVHSRKPLFGYTTMVFSIMGIVVLGLVVWAHHMFTSGTPPWMRLFF
TIATAFIAVPTGIKFFNWVATLWGGKISINSAMLFSCGFIINFVFGGITGVALAQVPFDIHVHDTYFVVAHFHYIVYGGT
VFIIFSSIYHWFPKVTGKLMNEKLGILHFAITFIGFNLCFAPQHWLGLNGMPRRVAEYDPQFQFVNQISSLGALLMAIST
IPFLINIYASIKNGKDSGDNPWDALTPEWLTTSPPPVENWEGEAPLVEEPYGYGKPISK
>Mature_538_residues
TILIDSQDSNNKSLQPKGWLRYFSFSLDHKVIGIQYLVCGFLFYLIGGTLASAIRIELTSPMSDFMPRDIYNQVLTLHGT
IMIFLWIVPVVNGAFGNYLIPFYVGARDMAFPRLNAVAFWLIPPSGLMLVASYFVEGAAQAGWTAYPPLSITTPQSGQII
WIMSVLLLGGSSIFGGINFIATIIKLRRPGLKLMQLPMYCWAMLGTSLLVVLSTPVLAGTLILLSFDIVAHTGFFNPVLG
GNVVVYQHLFWFYSHPAVYIMVLPAFGLVSEILPVHSRKPLFGYTTMVFSIMGIVVLGLVVWAHHMFTSGTPPWMRLFFT
IATAFIAVPTGIKFFNWVATLWGGKISINSAMLFSCGFIINFVFGGITGVALAQVPFDIHVHDTYFVVAHFHYIVYGGTV
FIIFSSIYHWFPKVTGKLMNEKLGILHFAITFIGFNLCFAPQHWLGLNGMPRRVAEYDPQFQFVNQISSLGALLMAISTI
PFLINIYASIKNGKDSGDNPWDALTPEWLTTSPPPVENWEGEAPLVEEPYGYGKPISK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=499, Percent_Identity=43.8877755511022, Blast_Score=378, Evalue=1e-105,
Organism=Escherichia coli, GI1786634, Length=537, Percent_Identity=40.0372439478585, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6226519, Length=525, Percent_Identity=38.0952380952381, Blast_Score=372, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6226524, Length=318, Percent_Identity=39.622641509434, Blast_Score=239, Evalue=7e-64,
Organism=Saccharomyces cerevisiae, GI6226523, Length=246, Percent_Identity=35.7723577235772, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59896; Mature: 59765

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILIDSQDSNNKSLQPKGWLRYFSFSLDHKVIGIQYLVCGFLFYLIGGTLASAIRIELT
CEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
SPMSDFMPRDIYNQVLTLHGTIMIFLWIVPVVNGAFGNYLIPFYVGARDMAFPRLNAVAF
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEE
WLIPPSGLMLVASYFVEGAAQAGWTAYPPLSITTPQSGQIIWIMSVLLLGGSSIFGGINF
EEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHHHH
IATIIKLRRPGLKLMQLPMYCWAMLGTSLLVVLSTPVLAGTLILLSFDIVAHTGFFNPVL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCC
GGNVVVYQHLFWFYSHPAVYIMVLPAFGLVSEILPVHSRKPLFGYTTMVFSIMGIVVLGL
CCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
VVWAHHMFTSGTPPWMRLFFTIATAFIAVPTGIKFFNWVATLWGGKISINSAMLFSCGFI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECHHHHHHHHHH
INFVFGGITGVALAQVPFDIHVHDTYFVVAHFHYIVYGGTVFIIFSSIYHWFPKVTGKLM
HHHHHHHHHHHHHHCCCEEEEECCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
NEKLGILHFAITFIGFNLCFAPQHWLGLNGMPRRVAEYDPQFQFVNQISSLGALLMAIST
HHHHHHHHHHHHHHHHHHEECCCHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
IPFLINIYASIKNGKDSGDNPWDALTPEWLTTSPPPVENWEGEAPLVEEPYGYGKPISK
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TILIDSQDSNNKSLQPKGWLRYFSFSLDHKVIGIQYLVCGFLFYLIGGTLASAIRIELT
EEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEC
SPMSDFMPRDIYNQVLTLHGTIMIFLWIVPVVNGAFGNYLIPFYVGARDMAFPRLNAVAF
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEE
WLIPPSGLMLVASYFVEGAAQAGWTAYPPLSITTPQSGQIIWIMSVLLLGGSSIFGGINF
EEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHHHH
IATIIKLRRPGLKLMQLPMYCWAMLGTSLLVVLSTPVLAGTLILLSFDIVAHTGFFNPVL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCC
GGNVVVYQHLFWFYSHPAVYIMVLPAFGLVSEILPVHSRKPLFGYTTMVFSIMGIVVLGL
CCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
VVWAHHMFTSGTPPWMRLFFTIATAFIAVPTGIKFFNWVATLWGGKISINSAMLFSCGFI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECHHHHHHHHHH
INFVFGGITGVALAQVPFDIHVHDTYFVVAHFHYIVYGGTVFIIFSSIYHWFPKVTGKLM
HHHHHHHHHHHHHHCCCEEEEECCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
NEKLGILHFAITFIGFNLCFAPQHWLGLNGMPRRVAEYDPQFQFVNQISSLGALLMAIST
HHHHHHHHHHHHHHHHHHEECCCHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
IPFLINIYASIKNGKDSGDNPWDALTPEWLTTSPPPVENWEGEAPLVEEPYGYGKPISK
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8399373 [H]