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The map label for this gene is minD [H]

Identifier: 123965588

GI number: 123965588

Start: 324916

End: 325731

Strand: Reverse

Name: minD [H]

Synonym: P9515_03531

Alternate gene names: 123965588

Gene position: 325731-324916 (Counterclockwise)

Preceding gene: 123965589

Following gene: 123965587

Centisome position: 19.11

GC content: 35.42

Gene sequence:

>816_bases
GTGCCGGAAAATAGTCGCACCATTTTAGTTTGTTCAGGTAAGGGTGGGGTAGGTAAAACCACACTGACAGCAAACCTAGG
CATTGCTCTAGCAAATAGTGGTGCAACAACAGCTGTTCTAGATGCTGATTTTGGATTGAGGAATTTAGACCTTCTTTTAG
GTTTAGAAAATCGTATTATTTATACTGCTCAAGATGTTCTCGACAAAAATTGTCGCCTTGACCAAGCCTTAGTTAGACAT
AAAAAGGAGCCTAATTTAGCTTTATTACCAGCTGGTGATCCTAGAATGCTTGATTGGATGAAACCTGAAGATATGAAACA
AATCAGTAAATTACTGAGTGAAAAGTTTGATTATGTTCTAGTAGATTGTCCTGCCGGAGTTGAAGATGGTTTTAAAAATG
CTCTGTCAGCCTGTAAAGAAGCAATAGTAGTAACGAATCCTGAATTATCAGCTGTTCGAGATGCAGATAGAGTTATAGGA
ATTTTAAATACTTCCGACATAAAGCCAATACAGTTAGTAATTAATAGAGTCCGTCCTAATATGATGGCTAATCAAGAAAT
GCTATCAATAGAAGATGTTCAGAGTATCCTTTCTTTGCCCTTACTTGGTATTGTTTTAGAGGATGAGCAAGTAATAATAA
GTACAAATAGAGGGGAGCCTCTGACACTATCTGATAATAAATCTCCAGCTAAAAAATGCTATTTAAATGTATCTCAAAGG
CTAACGGGAAAAGATATTCCTATTATCGATCCAAAAAATGAAGGACAAAGCATAAAAGATAAATTCATGAGATTAATGCA
AACAAAGATTTTTTAA

Upstream 100 bases:

>100_bases
AATAAACTAATAAAAAAAAATAAATTTAAGAATTACTTAACTTTTCTAAAATTTAACCTTTAAAATCTAGCTTATTATTT
GTAGAATTATTCATTAATTT

Downstream 100 bases:

>100_bases
AAAATTATGACTCTTAGAGACCTTATAAACAAATTGCTAGGCAGAGAAACGTCCAGTGCCAATACAGCAAGGGAAAGATT
GCAACTAGTTTTAGCTCATG

Product: putative septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MPENSRTILVCSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLENRIIYTAQDVLDKNCRLDQALVRH
KKEPNLALLPAGDPRMLDWMKPEDMKQISKLLSEKFDYVLVDCPAGVEDGFKNALSACKEAIVVTNPELSAVRDADRVIG
ILNTSDIKPIQLVINRVRPNMMANQEMLSIEDVQSILSLPLLGIVLEDEQVIISTNRGEPLTLSDNKSPAKKCYLNVSQR
LTGKDIPIIDPKNEGQSIKDKFMRLMQTKIF

Sequences:

>Translated_271_residues
MPENSRTILVCSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLENRIIYTAQDVLDKNCRLDQALVRH
KKEPNLALLPAGDPRMLDWMKPEDMKQISKLLSEKFDYVLVDCPAGVEDGFKNALSACKEAIVVTNPELSAVRDADRVIG
ILNTSDIKPIQLVINRVRPNMMANQEMLSIEDVQSILSLPLLGIVLEDEQVIISTNRGEPLTLSDNKSPAKKCYLNVSQR
LTGKDIPIIDPKNEGQSIKDKFMRLMQTKIF
>Mature_270_residues
PENSRTILVCSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLENRIIYTAQDVLDKNCRLDQALVRHK
KEPNLALLPAGDPRMLDWMKPEDMKQISKLLSEKFDYVLVDCPAGVEDGFKNALSACKEAIVVTNPELSAVRDADRVIGI
LNTSDIKPIQLVINRVRPNMMANQEMLSIEDVQSILSLPLLGIVLEDEQVIISTNRGEPLTLSDNKSPAKKCYLNVSQRL
TGKDIPIIDPKNEGQSIKDKFMRLMQTKIF

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=254, Percent_Identity=24.8031496062992, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1787423, Length=253, Percent_Identity=41.1067193675889, Blast_Score=189, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6322188, Length=182, Percent_Identity=27.4725274725275, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24667611, Length=184, Percent_Identity=29.3478260869565, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29797; Mature: 29666

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPENSRTILVCSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLENRII
CCCCCCEEEEECCCCCCCCEEEEEECCEEEECCCCEEEEEECCCCCCCEEEEEECCCCEE
YTAQDVLDKNCRLDQALVRHKKEPNLALLPAGDPRMLDWMKPEDMKQISKLLSEKFDYVL
EEEHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEE
VDCPAGVEDGFKNALSACKEAIVVTNPELSAVRDADRVIGILNTSDIKPIQLVINRVRPN
EECCCCHHHHHHHHHHHHHHEEEEECCCHHHHHCHHHEEEEECCCCCCHHHHHHHHHCCC
MMANQEMLSIEDVQSILSLPLLGIVLEDEQVIISTNRGEPLTLSDNKSPAKKCYLNVSQR
HHCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHH
LTGKDIPIIDPKNEGQSIKDKFMRLMQTKIF
CCCCCCCEECCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PENSRTILVCSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLENRII
CCCCCEEEEECCCCCCCCEEEEEECCEEEECCCCEEEEEECCCCCCCEEEEEECCCCEE
YTAQDVLDKNCRLDQALVRHKKEPNLALLPAGDPRMLDWMKPEDMKQISKLLSEKFDYVL
EEEHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEE
VDCPAGVEDGFKNALSACKEAIVVTNPELSAVRDADRVIGILNTSDIKPIQLVINRVRPN
EECCCCHHHHHHHHHHHHHHEEEEECCCHHHHHCHHHEEEEECCCCCCHHHHHHHHHCCC
MMANQEMLSIEDVQSILSLPLLGIVLEDEQVIISTNRGEPLTLSDNKSPAKKCYLNVSQR
HHCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHH
LTGKDIPIIDPKNEGQSIKDKFMRLMQTKIF
CCCCCCCEECCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]