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The map label for this gene is murB [H]

Identifier: 123965255

GI number: 123965255

Start: 21636

End: 22526

Strand: Reverse

Name: murB [H]

Synonym: P9515_00201

Alternate gene names: 123965255

Gene position: 22526-21636 (Counterclockwise)

Preceding gene: 123965256

Following gene: 123965254

Centisome position: 1.32

GC content: 30.08

Gene sequence:

>891_bases
ATGGAAAATATTAATTTAGAAGAGAAAATAAACCTTTCAAATTATACAACTATAAAAGTTGGTGGATTTGCAGAATATTT
TTCACAACCAAATGATGTTGATGAATTCATCAATTTAATAAAGTGGGCGCATGTAAATAATCAAAAATGTCGAATAATAG
GAGCTGGCTCAAATTTATTAATAAATAATATTTTCTTAAAAGGCTTAACTATATGCACAAAAAAAATGCGCTCTATCAAA
CTACAATCCGAGACTGGAATTGTAGTAGCAGAAGCTGGTGTAATGCTACCAAAAATGTCGAATATGCTTGCAAAACATGG
ATTGCAAGGCGGTGAGTGGACGGTAGGAATCCCAGGCACAGTAGGAGGTGCAATTTATATGAATGCAGGTTCAGAAAAAA
TGTCATTAGCAAATAATCTGATATCCGTTCAAGTTATCGATACTAAAACTCTTAAAATATTTGAAATTGAAAAAAATGAT
ATCAATTTTCAATATAGATTTAGTCCTTTTCAGCAAAATAATCTTTTAGTCATAAGTGCTAAACTACTTTTTGAGCCTAA
CGGAAATATTGAAAAGTTATTAGAAACTACAAAGAAAAATCTTAAACAAAAAACCGATAAACAGCCTTATGATTTACCGA
GCTTTGGAAGCGTTTTTAAAAATCCAACTAATACTTATGCGGGTCAATTAATTGAGGAATTAGGATTAAAAGGTTTTAAA
ATAGGTGGCGCGGAAATATCAACTATGCATGGAAATTTTATTGTTAATAAATCTTCTGCTAATTCAAAAGATATTTTAGA
TTTAATAACAGTAATTCAACAAAAAGTACTACAAAAGAAAGGGATTTTTCTTCAACCGGAAGTAAGAATGATCGGATTTG
ACTATCCTTAA

Upstream 100 bases:

>100_bases
AACGAAAGAAAATGATTTTATATTAAATATGGGTGCTGGAGATTGTCATAAACTATGGTCAATATTAAATAATAAAAATA
CTTAAAAGATTAAAAAAATA

Downstream 100 bases:

>100_bases
TTAAAGAAACATTTTTATCAAATGGCAGGTTTTGGACTTCCAAATTTTGGACAACTAACAGAAGCTTTTAAAAAAGCTAA
AGAAATTCAACAAAATGCTC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MENINLEEKINLSNYTTIKVGGFAEYFSQPNDVDEFINLIKWAHVNNQKCRIIGAGSNLLINNIFLKGLTICTKKMRSIK
LQSETGIVVAEAGVMLPKMSNMLAKHGLQGGEWTVGIPGTVGGAIYMNAGSEKMSLANNLISVQVIDTKTLKIFEIEKND
INFQYRFSPFQQNNLLVISAKLLFEPNGNIEKLLETTKKNLKQKTDKQPYDLPSFGSVFKNPTNTYAGQLIEELGLKGFK
IGGAEISTMHGNFIVNKSSANSKDILDLITVIQQKVLQKKGIFLQPEVRMIGFDYP

Sequences:

>Translated_296_residues
MENINLEEKINLSNYTTIKVGGFAEYFSQPNDVDEFINLIKWAHVNNQKCRIIGAGSNLLINNIFLKGLTICTKKMRSIK
LQSETGIVVAEAGVMLPKMSNMLAKHGLQGGEWTVGIPGTVGGAIYMNAGSEKMSLANNLISVQVIDTKTLKIFEIEKND
INFQYRFSPFQQNNLLVISAKLLFEPNGNIEKLLETTKKNLKQKTDKQPYDLPSFGSVFKNPTNTYAGQLIEELGLKGFK
IGGAEISTMHGNFIVNKSSANSKDILDLITVIQQKVLQKKGIFLQPEVRMIGFDYP
>Mature_296_residues
MENINLEEKINLSNYTTIKVGGFAEYFSQPNDVDEFINLIKWAHVNNQKCRIIGAGSNLLINNIFLKGLTICTKKMRSIK
LQSETGIVVAEAGVMLPKMSNMLAKHGLQGGEWTVGIPGTVGGAIYMNAGSEKMSLANNLISVQVIDTKTLKIFEIEKND
INFQYRFSPFQQNNLLVISAKLLFEPNGNIEKLLETTKKNLKQKTDKQPYDLPSFGSVFKNPTNTYAGQLIEELGLKGFK
IGGAEISTMHGNFIVNKSSANSKDILDLITVIQQKVLQKKGIFLQPEVRMIGFDYP

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32926; Mature: 32926

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENINLEEKINLSNYTTIKVGGFAEYFSQPNDVDEFINLIKWAHVNNQKCRIIGAGSNLL
CCCCCCHHEECCCCEEEEEECCHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEE
INNIFLKGLTICTKKMRSIKLQSETGIVVAEAGVMLPKMSNMLAKHGLQGGEWTVGIPGT
EHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCEECHHHHHHHHHCCCCCCCEEEECCCC
VGGAIYMNAGSEKMSLANNLISVQVIDTKTLKIFEIEKNDINFQYRFSPFQQNNLLVISA
CCCEEEEECCCHHHHHHCCEEEEEEEECCEEEEEEEECCCCCEEEEECCCCCCCEEEEEE
KLLFEPNGNIEKLLETTKKNLKQKTDKQPYDLPSFGSVFKNPTNTYAGQLIEELGLKGFK
EEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCEEE
IGGAEISTMHGNFIVNKSSANSKDILDLITVIQQKVLQKKGIFLQPEVRMIGFDYP
ECCEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCCC
>Mature Secondary Structure
MENINLEEKINLSNYTTIKVGGFAEYFSQPNDVDEFINLIKWAHVNNQKCRIIGAGSNLL
CCCCCCHHEECCCCEEEEEECCHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEE
INNIFLKGLTICTKKMRSIKLQSETGIVVAEAGVMLPKMSNMLAKHGLQGGEWTVGIPGT
EHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCEECHHHHHHHHHCCCCCCCEEEECCCC
VGGAIYMNAGSEKMSLANNLISVQVIDTKTLKIFEIEKNDINFQYRFSPFQQNNLLVISA
CCCEEEEECCCHHHHHHCCEEEEEEEECCEEEEEEEECCCCCEEEEECCCCCCCEEEEEE
KLLFEPNGNIEKLLETTKKNLKQKTDKQPYDLPSFGSVFKNPTNTYAGQLIEELGLKGFK
EEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCEEE
IGGAEISTMHGNFIVNKSSANSKDILDLITVIQQKVLQKKGIFLQPEVRMIGFDYP
ECCEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]