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The map label for this gene is argG [H]

Identifier: 123969449

GI number: 123969449

Start: 1656831

End: 1658045

Strand: Reverse

Name: argG [H]

Synonym: A9601_19171

Alternate gene names: 123969449

Gene position: 1658045-1656831 (Counterclockwise)

Preceding gene: 123969452

Following gene: 123969446

Centisome position: 99.29

GC content: 33.99

Gene sequence:

>1215_bases
ATGCAGCAGTTAAAAAAAGTTGTACTAGCTTATTCTGGTGGCGTAGATACGAGCGTTTGTATTCCATATTTAAAGAATGA
ATATGGAATTTCAGAAGTAGTTACTTTTGTAGCAGATCTTGGACAAGGCGAGGATTTAGAACTTGTTAGACAAAAAGCTT
TAAACTCTGGTGCATCTAAATCAATCGTTGGCAATTTAGTTAATAGTTTTGTTGAAAGATACGCTTTTCCAGCCATTAGA
GCAAATGCATTATATTTAGATAAATATCCTTTATCTACTGCTCTTGCTAGGCCTTTAATTGCTGAAAATCTCGTAAATAT
TGCTAGAGAGATTAATGCCGATGCAGTAGCTCATGGATGCACTGGTAAAGGGAATGATCAAGTTCGGTTCGATTTAGCAA
TTAACGCTTTAGGTCCTGATTTAAAAATAATTACTCCTGCAAGGGAGTGGAATATGAGTAGAGAAGAGGCAATATTGTAT
GGAGAAAAGTTTGGTATACCTGCACCAGTATCAAAAAAATCACCATATTCAATAGACGTTAACTTACTCGGTAGGAGTAT
TGAAGCAGGTATATTAGAAGACCCAATGCAAGAAGCACCTGAGGATATTTTTTCGATGACATCATCAGTTAATAATTCAC
CTGATTCTCATCAAGATATAGAAATTGTTTTCAAAAATGGGTTTCCAGTTGGAATTAATGATCAATTTTTAACTCCAGTA
GAGATCATTCAAAGAGCTAATAATCTTGCAGGTAAACACGGTTTTGGAAGAATAGATATGATTGAGGATCGAGTAGTAGG
AATTAAAAGTAGAGAGATTTACGAAACACCTGGCCTCTTACTTTTAATCAAAGCTCACAAAGAATTAGAGAGCATTACGT
TAAATCCTGATGTTATCGATTTTAAAGGAATGGTGGAAAAAAAATGGGGTCAATTAGTTTATCAAGGTTTTTGGTTTGGT
CCTCTTAAAGAAAGTTTAGATGCATTTATATCATCGACTCAAACTTCAGTAAATGGAAGAGTAAAAATTAGACTTTATAA
GGGAAACGCAATAGTCATTGGGAGAATGTCGGAAAATAATTCACTTTACAGGGAAGATTTGGCAACTTACAGCAAAGATG
ATGTATTTAATCATTCTCTAGCAGAGGGTTTTATTTATATGTGGGGTATGTCTAATAAAATATGGGCTGAGTTAAATTCA
AAAACAAAAGATTAA

Upstream 100 bases:

>100_bases
GTTTTTGGTCCAGCTCTTTTAGTTACAATAGTATTAGTCTTTAATAAGTATTCAAATTCTTAATTACGTCAAAAAATTTA
AATTTATGGAGCAAATTTAG

Downstream 100 bases:

>100_bases
CATTTAAGATTCTGCATTTTCTTTAGTGCCAGCATCATCTTTGCTCGAAGTTGAACTATCTGCACTTGCTACTGGTTGTT
TTTCTTTAGATTCAACTTTC

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MQQLKKVVLAYSGGVDTSVCIPYLKNEYGISEVVTFVADLGQGEDLELVRQKALNSGASKSIVGNLVNSFVERYAFPAIR
ANALYLDKYPLSTALARPLIAENLVNIAREINADAVAHGCTGKGNDQVRFDLAINALGPDLKIITPAREWNMSREEAILY
GEKFGIPAPVSKKSPYSIDVNLLGRSIEAGILEDPMQEAPEDIFSMTSSVNNSPDSHQDIEIVFKNGFPVGINDQFLTPV
EIIQRANNLAGKHGFGRIDMIEDRVVGIKSREIYETPGLLLLIKAHKELESITLNPDVIDFKGMVEKKWGQLVYQGFWFG
PLKESLDAFISSTQTSVNGRVKIRLYKGNAIVIGRMSENNSLYREDLATYSKDDVFNHSLAEGFIYMWGMSNKIWAELNS
KTKD

Sequences:

>Translated_404_residues
MQQLKKVVLAYSGGVDTSVCIPYLKNEYGISEVVTFVADLGQGEDLELVRQKALNSGASKSIVGNLVNSFVERYAFPAIR
ANALYLDKYPLSTALARPLIAENLVNIAREINADAVAHGCTGKGNDQVRFDLAINALGPDLKIITPAREWNMSREEAILY
GEKFGIPAPVSKKSPYSIDVNLLGRSIEAGILEDPMQEAPEDIFSMTSSVNNSPDSHQDIEIVFKNGFPVGINDQFLTPV
EIIQRANNLAGKHGFGRIDMIEDRVVGIKSREIYETPGLLLLIKAHKELESITLNPDVIDFKGMVEKKWGQLVYQGFWFG
PLKESLDAFISSTQTSVNGRVKIRLYKGNAIVIGRMSENNSLYREDLATYSKDDVFNHSLAEGFIYMWGMSNKIWAELNS
KTKD
>Mature_404_residues
MQQLKKVVLAYSGGVDTSVCIPYLKNEYGISEVVTFVADLGQGEDLELVRQKALNSGASKSIVGNLVNSFVERYAFPAIR
ANALYLDKYPLSTALARPLIAENLVNIAREINADAVAHGCTGKGNDQVRFDLAINALGPDLKIITPAREWNMSREEAILY
GEKFGIPAPVSKKSPYSIDVNLLGRSIEAGILEDPMQEAPEDIFSMTSSVNNSPDSHQDIEIVFKNGFPVGINDQFLTPV
EIIQRANNLAGKHGFGRIDMIEDRVVGIKSREIYETPGLLLLIKAHKELESITLNPDVIDFKGMVEKKWGQLVYQGFWFG
PLKESLDAFISSTQTSVNGRVKIRLYKGNAIVIGRMSENNSLYREDLATYSKDDVFNHSLAEGFIYMWGMSNKIWAELNS
KTKD

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=414, Percent_Identity=40.5797101449275, Blast_Score=287, Evalue=1e-77,
Organism=Homo sapiens, GI16950633, Length=414, Percent_Identity=40.5797101449275, Blast_Score=287, Evalue=1e-77,
Organism=Escherichia coli, GI1789563, Length=395, Percent_Identity=28.6075949367089, Blast_Score=131, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6324514, Length=413, Percent_Identity=39.7094430992736, Blast_Score=290, Evalue=2e-79,
Organism=Drosophila melanogaster, GI21358151, Length=392, Percent_Identity=39.2857142857143, Blast_Score=274, Evalue=7e-74,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 44804; Mature: 44804

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLKKVVLAYSGGVDTSVCIPYLKNEYGISEVVTFVADLGQGEDLELVRQKALNSGASK
CHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHH
SIVGNLVNSFVERYAFPAIRANALYLDKYPLSTALARPLIAENLVNIAREINADAVAHGC
HHHHHHHHHHHHHHCCCHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
TGKGNDQVRFDLAINALGPDLKIITPAREWNMSREEAILYGEKFGIPAPVSKKSPYSIDV
CCCCCCEEEEEEEEECCCCCEEEECCHHHHCCCHHHEEEEHHHCCCCCCCCCCCCCEEEE
NLLGRSIEAGILEDPMQEAPEDIFSMTSSVNNSPDSHQDIEIVFKNGFPVGINDQFLTPV
EEECCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCHH
EIIQRANNLAGKHGFGRIDMIEDRVVGIKSREIYETPGLLLLIKAHKELESITLNPDVID
HHHHHHHHHCCCCCCCCCEEECCCEECCCCCEEECCCCEEEEEECCCCHHHEECCCCCCC
FKGMVEKKWGQLVYQGFWFGPLKESLDAFISSTQTSVNGRVKIRLYKGNAIVIGRMSENN
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEEEEEECCCC
SLYREDLATYSKDDVFNHSLAEGFIYMWGMSNKIWAELNSKTKD
CHHHHHHHHCCCCHHHCHHHHCCEEEEECCCCHHHHCCCCCCCC
>Mature Secondary Structure
MQQLKKVVLAYSGGVDTSVCIPYLKNEYGISEVVTFVADLGQGEDLELVRQKALNSGASK
CHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHH
SIVGNLVNSFVERYAFPAIRANALYLDKYPLSTALARPLIAENLVNIAREINADAVAHGC
HHHHHHHHHHHHHHCCCHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
TGKGNDQVRFDLAINALGPDLKIITPAREWNMSREEAILYGEKFGIPAPVSKKSPYSIDV
CCCCCCEEEEEEEEECCCCCEEEECCHHHHCCCHHHEEEEHHHCCCCCCCCCCCCCEEEE
NLLGRSIEAGILEDPMQEAPEDIFSMTSSVNNSPDSHQDIEIVFKNGFPVGINDQFLTPV
EEECCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCHH
EIIQRANNLAGKHGFGRIDMIEDRVVGIKSREIYETPGLLLLIKAHKELESITLNPDVID
HHHHHHHHHCCCCCCCCCEEECCCEECCCCCEEECCCCEEEEEECCCCHHHEECCCCCCC
FKGMVEKKWGQLVYQGFWFGPLKESLDAFISSTQTSVNGRVKIRLYKGNAIVIGRMSENN
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEEEEEECCCC
SLYREDLATYSKDDVFNHSLAEGFIYMWGMSNKIWAELNSKTKD
CHHHHHHHHCCCCHHHCHHHHCCEEEEECCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA