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The map label for this gene is infC [H]

Identifier: 123969378

GI number: 123969378

Start: 1576346

End: 1576918

Strand: Direct

Name: infC [H]

Synonym: A9601_18461

Alternate gene names: 123969378

Gene position: 1576346-1576918 (Clockwise)

Preceding gene: 123969377

Following gene: 123969379

Centisome position: 94.4

GC content: 33.68

Gene sequence:

>573_bases
ATGCCACCACGCCCACGTTTTGACCGCCGAGCTCCAGTAAGAGAGCTACCAAATATAAATGAAAGAATAAAATACCCTCA
ATTGAGAGTTGTTGATTCAGATGGGAAACAATTAGGTGTCATAGATAGATTAAAAGCATTAGAAATAGCCTCTCAAAGAG
AACTTGATTTAGTTTTGGTGAGCGAAAAAGCAAATCCTCCTGTTTGCAGAATAATGGATTACGGAAAATATAAATTTGAA
CAAGAAAAGAAAGCTAAAGAAGCAAGGAAAAAATCCCATCAAACAGAAGTTAAAGAAGTAAAAATGAGGTACAAAATTGA
CAAGCATGATTATGATGTCCGCATAGGTCAAGCTACTAAATTTTTAAAATCAGGAGACAAAGTAAAATGCACTGTAATAT
TTAGGGGTAGAGAAATTCAACACTCAAATTTAGCTGAAACACTTCTTTTGAAAATGGCTAATGATTTAGAAGAACAATCA
GAAGTTCAACAAAAACCAAAAAGAGAAGGGAGAAACATGATTATGTTTTTAAGCCCTCGAAAAACTCCTCTTATTAAAAA
AGATGATGGTTGA

Upstream 100 bases:

>100_bases
AACCTTCTAAAAGATGCAATAATTAAGATAGAGTCTTTTTTAAGCTAACTTTATAAAAATAGATTTTTTCATCATCCACT
CAAATTATTAAATTAACTGA

Downstream 100 bases:

>100_bases
AAAGTTGCTATCAAAAAATATGACGAATGTTAAAGTGTCAATATGGTCAAAAATGAATTAGTTAGGGTTTTTAGAAAGTG
AGATTCCATATTCAACAAGA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MPPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLKALEIASQRELDLVLVSEKANPPVCRIMDYGKYKFE
QEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATKFLKSGDKVKCTVIFRGREIQHSNLAETLLLKMANDLEEQS
EVQQKPKREGRNMIMFLSPRKTPLIKKDDG

Sequences:

>Translated_190_residues
MPPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLKALEIASQRELDLVLVSEKANPPVCRIMDYGKYKFE
QEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATKFLKSGDKVKCTVIFRGREIQHSNLAETLLLKMANDLEEQS
EVQQKPKREGRNMIMFLSPRKTPLIKKDDG
>Mature_189_residues
PPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLKALEIASQRELDLVLVSEKANPPVCRIMDYGKYKFEQ
EKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATKFLKSGDKVKCTVIFRGREIQHSNLAETLLLKMANDLEEQSE
VQQKPKREGRNMIMFLSPRKTPLIKKDDG

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=167, Percent_Identity=44.311377245509, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 22229; Mature: 22098

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLKALEIASQRELDLVLV
CCCCCCCCCCCCHHHCCCCHHHCCCCEEEEECCCCCEECHHHHHHHHHHHCCCCEEEEEE
SEKANPPVCRIMDYGKYKFEQEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATK
ECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECHHHH
FLKSGDKVKCTVIFRGREIQHSNLAETLLLKMANDLEEQSEVQQKPKREGRNMIMFLSPR
HHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KTPLIKKDDG
CCCCCCCCCC
>Mature Secondary Structure 
PPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLKALEIASQRELDLVLV
CCCCCCCCCCCHHHCCCCHHHCCCCEEEEECCCCCEECHHHHHHHHHHHCCCCEEEEEE
SEKANPPVCRIMDYGKYKFEQEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATK
ECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECHHHH
FLKSGDKVKCTVIFRGREIQHSNLAETLLLKMANDLEEQSEVQQKPKREGRNMIMFLSPR
HHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KTPLIKKDDG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA