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The map label for this gene is dnaK [H]

Identifier: 123969166

GI number: 123969166

Start: 1379642

End: 1381210

Strand: Direct

Name: dnaK [H]

Synonym: A9601_16341

Alternate gene names: 123969166

Gene position: 1379642-1381210 (Clockwise)

Preceding gene: 123969162

Following gene: 123969168

Centisome position: 82.62

GC content: 29.57

Gene sequence:

>1569_bases
ATGGAAAAAAGTTTATCTGGAACACTTGCTATTGATTTAGGGAACACTAATACTGTTGTAGCTTTTCAAGATCAAAAAGA
TATAAATTCTGTTTTAGTTGAAATACCGAATATTACATCTTCTCCAGGAGTTATTCCTTCAGCAGTTTGGTTCGAGGAAC
CTTCAAAAATTACTAAAATTGGTATTAGTGCTCTAGAGATGAGAGACAACTCAAATTCTGATTTATTTTTTCATTCGAAC
TTTAAAAGATTAATTGGAAATTCTATTGAAAAAAATAACCAAAAAAATATTTTAAACCCTAATGAATGTGGCGAAAAATT
TTTTCAAATTTTGTGGGCAAATATTCCTCAAAAGTATGAGATCAAAAGACTTGTTTTAACTGCTCCTATAGATACATACA
AGGGGTACAGAGAATGGTTAGTTAACCTTTGCGAGGATATATCTGTAGATGAGATAGCTCTTGTTGATGAACCTACTGCC
GCAAGTTTAGGAATAAATATACCATTTGGCTCAAAAATTATGACATTAGATATTGGGGGAAGTACAATCGATATGAATAT
AGTCAAAATAGAGGGAGGAGAAGGAAAATCTGGTCCAATAGCTGAACTTTTAAGATTTAAGGGTAATGATGTAAGCTCAA
TTTCAAAACAAAAAATAAGGTGTGCTGAAATAATTGGCAAAACAGGCTCAAAAATTGGTGGGAAAGATATTGATCAATGG
TTAGTTAATTATTTTATTCCAGGCAATAATTCTACTACTAATCTTTTTAATGCAGAAGCGATAAAATGTAAACTCAGTTC
ATCTGCAATCAAATATGATGATAAATATCCCATAAAATTATTTACTGAACAATCTGAAGAAAAAGAATTTTACCTAAGTA
AAGAAATATTTGAGAACATACTCATTGAAAATAATTTTCTTAAACACCTTAACTCTTTGCTCAAAGATTTATTAAATCAA
TCAAGAGGAAAATTTTGCACAGTTGACGATTTAAATGCAATTGTTTTGGTAGGTGGAGGAACTCAAATACCATTAATTAA
AGAATGGATAACAAAAAAAATTTCGAAAATTCAAATAAAGTCTCCACCTCCTATCGAATCAATAGCTTTGGGAGCTTTAG
CAATGACCCCAGGGGTAAAAATTAAAGACATATTAAACAAAGGATTATCTATAAGATTATTTAATAAAAGAGAACAAAAA
CACTTTTGGCATCCTATTTTTTGCAAAGGTCAAACATGGCCAACTGAAAAACCATTTAAAATAATCCTTCAACCGAGTAA
AAATAATCAGAAAATATTCGAAATCATTATTGGGGAAACACAAAAAGAAAGAGCATATGATGTCATTTTCGAAAATGGAC
TTCCAAAATTATCAGAAGTTCAAAATGAAGAAGAAATTATAAAATGGGACAAAACTCCACTCAAAATAATACTGAAAAAA
GGATCGAATATTGGACAAGACAACTTAAAACTTTTTTTTAAAATCACGGAAAGTGCTGATTTATTAGTTAAGTGTTTTGA
TATTAAAGATGAATGTTTAGGCGAATATAATTTAGGAAATATCTTCTAA

Upstream 100 bases:

>100_bases
TTAAAAAAAATTTTTTACTATAATAATGTATTTTACAATTTATTCGACCGTTTCAAAACATAAATTACAAAAAGAACTTA
ATTGATTTAAATAATTTCAT

Downstream 100 bases:

>100_bases
AAGCTAGCTATTCAAGAAGACTCCTTCTTCATTATCAACTCTATTTAAACGTAAACTAATACTTTCAATTTTACTAGTAG
GCACTTTTTTACCACAAAAA

Product: HSP70 family molecular chaperone

Products: NA

Alternate protein names: HSP70; Heat shock 70 kDa protein; Heat shock protein 70 [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MEKSLSGTLAIDLGNTNTVVAFQDQKDINSVLVEIPNITSSPGVIPSAVWFEEPSKITKIGISALEMRDNSNSDLFFHSN
FKRLIGNSIEKNNQKNILNPNECGEKFFQILWANIPQKYEIKRLVLTAPIDTYKGYREWLVNLCEDISVDEIALVDEPTA
ASLGINIPFGSKIMTLDIGGSTIDMNIVKIEGGEGKSGPIAELLRFKGNDVSSISKQKIRCAEIIGKTGSKIGGKDIDQW
LVNYFIPGNNSTTNLFNAEAIKCKLSSSAIKYDDKYPIKLFTEQSEEKEFYLSKEIFENILIENNFLKHLNSLLKDLLNQ
SRGKFCTVDDLNAIVLVGGGTQIPLIKEWITKKISKIQIKSPPPIESIALGALAMTPGVKIKDILNKGLSIRLFNKREQK
HFWHPIFCKGQTWPTEKPFKIILQPSKNNQKIFEIIIGETQKERAYDVIFENGLPKLSEVQNEEEIIKWDKTPLKIILKK
GSNIGQDNLKLFFKITESADLLVKCFDIKDECLGEYNLGNIF

Sequences:

>Translated_522_residues
MEKSLSGTLAIDLGNTNTVVAFQDQKDINSVLVEIPNITSSPGVIPSAVWFEEPSKITKIGISALEMRDNSNSDLFFHSN
FKRLIGNSIEKNNQKNILNPNECGEKFFQILWANIPQKYEIKRLVLTAPIDTYKGYREWLVNLCEDISVDEIALVDEPTA
ASLGINIPFGSKIMTLDIGGSTIDMNIVKIEGGEGKSGPIAELLRFKGNDVSSISKQKIRCAEIIGKTGSKIGGKDIDQW
LVNYFIPGNNSTTNLFNAEAIKCKLSSSAIKYDDKYPIKLFTEQSEEKEFYLSKEIFENILIENNFLKHLNSLLKDLLNQ
SRGKFCTVDDLNAIVLVGGGTQIPLIKEWITKKISKIQIKSPPPIESIALGALAMTPGVKIKDILNKGLSIRLFNKREQK
HFWHPIFCKGQTWPTEKPFKIILQPSKNNQKIFEIIIGETQKERAYDVIFENGLPKLSEVQNEEEIIKWDKTPLKIILKK
GSNIGQDNLKLFFKITESADLLVKCFDIKDECLGEYNLGNIF
>Mature_522_residues
MEKSLSGTLAIDLGNTNTVVAFQDQKDINSVLVEIPNITSSPGVIPSAVWFEEPSKITKIGISALEMRDNSNSDLFFHSN
FKRLIGNSIEKNNQKNILNPNECGEKFFQILWANIPQKYEIKRLVLTAPIDTYKGYREWLVNLCEDISVDEIALVDEPTA
ASLGINIPFGSKIMTLDIGGSTIDMNIVKIEGGEGKSGPIAELLRFKGNDVSSISKQKIRCAEIIGKTGSKIGGKDIDQW
LVNYFIPGNNSTTNLFNAEAIKCKLSSSAIKYDDKYPIKLFTEQSEEKEFYLSKEIFENILIENNFLKHLNSLLKDLLNQ
SRGKFCTVDDLNAIVLVGGGTQIPLIKEWITKKISKIQIKSPPPIESIALGALAMTPGVKIKDILNKGLSIRLFNKREQK
HFWHPIFCKGQTWPTEKPFKIILQPSKNNQKIFEIIIGETQKERAYDVIFENGLPKLSEVQNEEEIIKWDKTPLKIILKK
GSNIGQDNLKLFFKITESADLLVKCFDIKDECLGEYNLGNIF

Specific function: Acts as a chaperone [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Escherichia coli, GI1786870, Length=431, Percent_Identity=23.8979118329466, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012725
- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 58681; Mature: 58681

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS01036 HSP70_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKSLSGTLAIDLGNTNTVVAFQDQKDINSVLVEIPNITSSPGVIPSAVWFEEPSKITKI
CCCCCCCEEEEEECCCEEEEEECCCCCCCHHHEECCCCCCCCCCCCCHHCCCCCCHHHHH
GISALEMRDNSNSDLFFHSNFKRLIGNSIEKNNQKNILNPNECGEKFFQILWANIPQKYE
CCEEEEECCCCCCCEEEECCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEE
IKRLVLTAPIDTYKGYREWLVNLCEDISVDEIALVDEPTAASLGINIPFGSKIMTLDIGG
EEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCEEEEEEECC
STIDMNIVKIEGGEGKSGPIAELLRFKGNDVSSISKQKIRCAEIIGKTGSKIGGKDIDQW
CEEEEEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LVNYFIPGNNSTTNLFNAEAIKCKLSSSAIKYDDKYPIKLFTEQSEEKEFYLSKEIFENI
HHEEEECCCCCCCEEECCEEEEEEECCCEEECCCCCCEEEEECCCCCHHHHHHHHHHHHH
LIENNFLKHLNSLLKDLLNQSRGKFCTVDDLNAIVLVGGGTQIPLIKEWITKKISKIQIK
HHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHEEEEC
SPPPIESIALGALAMTPGVKIKDILNKGLSIRLFNKREQKHFWHPIFCKGQTWPTEKPFK
CCCCHHHHHHHHHHCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCEE
IILQPSKNNQKIFEIIIGETQKERAYDVIFENGLPKLSEVQNEEEIIKWDKTPLKIILKK
EEEECCCCCCEEEEEEECCCCCHHHHHHEECCCCCHHHHHCCCHHHEECCCCCEEEEEEC
GSNIGQDNLKLFFKITESADLLVKCFDIKDECLGEYNLGNIF
CCCCCCCCEEEEEEEECCCCEEEEEECCCHHHCCCCCCCCCC
>Mature Secondary Structure
MEKSLSGTLAIDLGNTNTVVAFQDQKDINSVLVEIPNITSSPGVIPSAVWFEEPSKITKI
CCCCCCCEEEEEECCCEEEEEECCCCCCCHHHEECCCCCCCCCCCCCHHCCCCCCHHHHH
GISALEMRDNSNSDLFFHSNFKRLIGNSIEKNNQKNILNPNECGEKFFQILWANIPQKYE
CCEEEEECCCCCCCEEEECCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEE
IKRLVLTAPIDTYKGYREWLVNLCEDISVDEIALVDEPTAASLGINIPFGSKIMTLDIGG
EEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCEEEEEEECC
STIDMNIVKIEGGEGKSGPIAELLRFKGNDVSSISKQKIRCAEIIGKTGSKIGGKDIDQW
CEEEEEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LVNYFIPGNNSTTNLFNAEAIKCKLSSSAIKYDDKYPIKLFTEQSEEKEFYLSKEIFENI
HHEEEECCCCCCCEEECCEEEEEEECCCEEECCCCCCEEEEECCCCCHHHHHHHHHHHHH
LIENNFLKHLNSLLKDLLNQSRGKFCTVDDLNAIVLVGGGTQIPLIKEWITKKISKIQIK
HHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHEEEEC
SPPPIESIALGALAMTPGVKIKDILNKGLSIRLFNKREQKHFWHPIFCKGQTWPTEKPFK
CCCCHHHHHHHHHHCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCEE
IILQPSKNNQKIFEIIIGETQKERAYDVIFENGLPKLSEVQNEEEIIKWDKTPLKIILKK
EEEECCCCCCEEEEEEECCCCCHHHHHHEECCCCCHHHHHCCCHHHEECCCCCEEEEEEC
GSNIGQDNLKLFFKITESADLLVKCFDIKDECLGEYNLGNIF
CCCCCCCCEEEEEEEECCCCEEEEEECCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA