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The map label for this gene is ygcW [C]

Identifier: 123969096

GI number: 123969096

Start: 1340270

End: 1341199

Strand: Direct

Name: ygcW [C]

Synonym: A9601_15641

Alternate gene names: 123969096

Gene position: 1340270-1341199 (Clockwise)

Preceding gene: 123969095

Following gene: 123969098

Centisome position: 80.26

GC content: 33.12

Gene sequence:

>930_bases
ATGACTGCCACTATTTCAAGACCTAAAATCTCTAACTGGGAAACATCTAATATTCCAAACCTTACAGGCAAAACAGCGCT
AATTACTGGTGCGAATAGTGGTCTTGGATACTACACTGCAAAGGCCTTAGCAGAAAAAAATGCTCATATCGTTATAGCTT
GTAGATCGTTTGAAAAAGCTAATCAAACTATCAAAAAACTTAAAGGTCTTAATCCTGAAGGAATATTTACACCTTTAGAA
TTAGATTTGTCAGATTTAAAAAATATTGTTGAAGTTCAGTCCAAAATTTTTGATAATTTTGAAAATTTGGATTTACTAAT
CAATAATGCAGGCATTATGCATCCGCCTAAAACACTTAGTGCCCAGGGATATGAAATACAATTTGCAGTTAATCATTTAG
CTCATATGCTTTTGACACTAAAGCTACTTCCAATTATTGAAAAAAAAGAAGAATCTAGAATAGTGACGGTTACTTCTGGA
GCACAATTTTTTGGCAAAGTTGGTTGGAAAAATCTTAAAGCTGAGAACTATTACAATAAATGGGAATCTTACTCTAATAG
CAAATTAGCGAATGTAATGTTTGCTTTGGAACTAAATGAAAACTTAAAGCACAAAAATATACTTTCTTTAGCTGCTCACC
CAGGAATTGCAAAAACAAATCTCTTTACTGCTCAAAAACCTAACCCTAGTCCATTAGAAACATTTTCATTGGAATTATTT
AGCCCTATTTTTCAAACTGCTGAGATGGGTGCTTTACCTCAACTTTTTGCAGCTACTTCACCAGACGCAAGAGGTGGTGA
TCATTATGGACCTAGATTTAATTTCAGAGGTCATCCAAAACTATCCCCTACTTCTCCTTTCGCCATGAATAAAAAAGAAA
GAAAAAATTTATGGGAAAAAAGCCTTGAAATACTTAAAAACTTCTTATAA

Upstream 100 bases:

>100_bases
AGTACCTTCAAGAAGAGCTCACGATACTGACTTCCAGTATTTACAGTGGAAAAGTAATTATATTGTGGTTAAATTCCATA
GCAATTTGCAGGATTAATAA

Downstream 100 bases:

>100_bases
ATTTTTCATTTTTACTAATTTTAGAAAATATTTTAAGATATGTAATTCACTTTCTGAGAGTTTCATAAATTCTGTTAAGG
CATCATAATTTTTTTCATCA

Product: short-chain dehydrogenase/reductase

Products: protochlorophyllide; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTATISRPKISNWETSNIPNLTGKTALITGANSGLGYYTAKALAEKNAHIVIACRSFEKANQTIKKLKGLNPEGIFTPLE
LDLSDLKNIVEVQSKIFDNFENLDLLINNAGIMHPPKTLSAQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSG
AQFFGKVGWKNLKAENYYNKWESYSNSKLANVMFALELNENLKHKNILSLAAHPGIAKTNLFTAQKPNPSPLETFSLELF
SPIFQTAEMGALPQLFAATSPDARGGDHYGPRFNFRGHPKLSPTSPFAMNKKERKNLWEKSLEILKNFL

Sequences:

>Translated_309_residues
MTATISRPKISNWETSNIPNLTGKTALITGANSGLGYYTAKALAEKNAHIVIACRSFEKANQTIKKLKGLNPEGIFTPLE
LDLSDLKNIVEVQSKIFDNFENLDLLINNAGIMHPPKTLSAQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSG
AQFFGKVGWKNLKAENYYNKWESYSNSKLANVMFALELNENLKHKNILSLAAHPGIAKTNLFTAQKPNPSPLETFSLELF
SPIFQTAEMGALPQLFAATSPDARGGDHYGPRFNFRGHPKLSPTSPFAMNKKERKNLWEKSLEILKNFL
>Mature_308_residues
TATISRPKISNWETSNIPNLTGKTALITGANSGLGYYTAKALAEKNAHIVIACRSFEKANQTIKKLKGLNPEGIFTPLEL
DLSDLKNIVEVQSKIFDNFENLDLLINNAGIMHPPKTLSAQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSGA
QFFGKVGWKNLKAENYYNKWESYSNSKLANVMFALELNENLKHKNILSLAAHPGIAKTNLFTAQKPNPSPLETFSLELFS
PIFQTAEMGALPQLFAATSPDARGGDHYGPRFNFRGHPKLSPTSPFAMNKKERKNLWEKSLEILKNFL

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI166795268, Length=307, Percent_Identity=32.5732899022801, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI225579078, Length=288, Percent_Identity=35.0694444444444, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI186928839, Length=288, Percent_Identity=34.375, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI10190746, Length=321, Percent_Identity=33.9563862928349, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI7706523, Length=299, Percent_Identity=27.7591973244147, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI146231950, Length=290, Percent_Identity=32.7586206896552, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI19923931, Length=254, Percent_Identity=33.0708661417323, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI193804850, Length=294, Percent_Identity=30.6122448979592, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI13375997, Length=169, Percent_Identity=33.1360946745562, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI72534732, Length=169, Percent_Identity=33.1360946745562, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI142976729, Length=185, Percent_Identity=30.8108108108108, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI40548397, Length=209, Percent_Identity=28.2296650717703, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI214010158, Length=209, Percent_Identity=28.2296650717703, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI214010156, Length=209, Percent_Identity=28.2296650717703, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI22758144, Length=209, Percent_Identity=28.2296650717703, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI87082160, Length=218, Percent_Identity=27.9816513761468, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787335, Length=207, Percent_Identity=27.536231884058, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17558006, Length=293, Percent_Identity=29.0102389078498, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17532791, Length=307, Percent_Identity=28.3387622149837, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI193207620, Length=307, Percent_Identity=29.9674267100977, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17532805, Length=302, Percent_Identity=27.8145695364238, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI72001364, Length=293, Percent_Identity=30.3754266211604, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71992402, Length=254, Percent_Identity=28.3464566929134, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17505416, Length=214, Percent_Identity=31.7757009345794, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17535059, Length=253, Percent_Identity=28.4584980237154, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI32565532, Length=207, Percent_Identity=29.951690821256, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533174, Length=296, Percent_Identity=28.0405405405405, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533172, Length=293, Percent_Identity=27.6450511945392, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=177, Percent_Identity=29.9435028248588, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17558996, Length=215, Percent_Identity=28.3720930232558, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324820, Length=320, Percent_Identity=27.5, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6322227, Length=270, Percent_Identity=24.8148148148148, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI22024069, Length=286, Percent_Identity=36.3636363636364, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI28573296, Length=247, Percent_Identity=37.246963562753, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI45554248, Length=288, Percent_Identity=32.9861111111111, Blast_Score=141, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24640117, Length=288, Percent_Identity=32.9861111111111, Blast_Score=141, Evalue=5e-34,
Organism=Drosophila melanogaster, GI19921754, Length=284, Percent_Identity=36.6197183098592, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24586328, Length=285, Percent_Identity=31.9298245614035, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI161076371, Length=251, Percent_Identity=34.6613545816733, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI20129347, Length=255, Percent_Identity=30.9803921568627, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24656154, Length=292, Percent_Identity=31.1643835616438, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI19922628, Length=292, Percent_Identity=31.1643835616438, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24647946, Length=287, Percent_Identity=29.9651567944251, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI45553409, Length=287, Percent_Identity=29.9651567944251, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24647948, Length=287, Percent_Identity=29.9651567944251, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24647931, Length=324, Percent_Identity=25.3086419753086, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21358495, Length=206, Percent_Identity=29.126213592233, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.3.1.33

Molecular weight: Translated: 34456; Mature: 34325

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATISRPKISNWETSNIPNLTGKTALITGANSGLGYYTAKALAEKNAHIVIACRSFEKA
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCHHH
NQTIKKLKGLNPEGIFTPLELDLSDLKNIVEVQSKIFDNFENLDLLINNAGIMHPPKTLS
HHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
AQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSGAQFFGKVGWKNLKAENYYNK
CCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHCCCCCCCHHHHHH
WESYSNSKLANVMFALELNENLKHKNILSLAAHPGIAKTNLFTAQKPNPSPLETFSLELF
HHHCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHH
SPIFQTAEMGALPQLFAATSPDARGGDHYGPRFNFRGHPKLSPTSPFAMNKKERKNLWEK
HHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
SLEILKNFL
HHHHHHHCC
>Mature Secondary Structure 
TATISRPKISNWETSNIPNLTGKTALITGANSGLGYYTAKALAEKNAHIVIACRSFEKA
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCHHH
NQTIKKLKGLNPEGIFTPLELDLSDLKNIVEVQSKIFDNFENLDLLINNAGIMHPPKTLS
HHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
AQGYEIQFAVNHLAHMLLTLKLLPIIEKKEESRIVTVTSGAQFFGKVGWKNLKAENYYNK
CCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHCCCCCCCHHHHHH
WESYSNSKLANVMFALELNENLKHKNILSLAAHPGIAKTNLFTAQKPNPSPLETFSLELF
HHHCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHH
SPIFQTAEMGALPQLFAATSPDARGGDHYGPRFNFRGHPKLSPTSPFAMNKKERKNLWEK
HHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
SLEILKNFL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: chlorophyllide a; NADP+

Specific reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]