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The map label for this gene is purC [H]

Identifier: 123969071

GI number: 123969071

Start: 1319228

End: 1319545

Strand: Reverse

Name: purC [H]

Synonym: A9601_15391

Alternate gene names: 123969071

Gene position: 1319545-1319228 (Counterclockwise)

Preceding gene: 123969072

Following gene: 123969070

Centisome position: 79.02

GC content: 28.62

Gene sequence:

>318_bases
ATGAACATACTAAGTCCTCATGATTTAGAGTTAATAATAAAGTTAACTTTGAAGATTAATGTAATCCTGAAAAGTTTTTT
TAAAAGTATTCAACTTCAACTTGTGGATTTCAAGTTGGAATTTGGTTATGACTTTAGAAATAATATACTTCTTGCGGACG
AAATAAGCCCTGATAATTGTAGATTGTGGGATTTAAATCAAAAAAATGATACAATCGTAAGTCTAGATAAAGATAGATTT
AGGAATGATTTAGGTGGTCTAATTGAAGCTTATACTGAAATTCACCGAAGAATGAACGATTTTCTACTACCTAATTGA

Upstream 100 bases:

>100_bases
TATTAAACCTGGAACTCCCCTATCAAAACCACTCATTGATATCTATCTTAAAAATGATGAACTTAATGATCCCCTTATCA
CAAAAGATAGAATTGAATTA

Downstream 100 bases:

>100_bases
ATAAATAATGACTTATTTATCTTGATAAAAAGTATTATGCAAAAACATTTTTTAAAATTTGGAAAGGTTTTCACAAATGT
TGCCTGCTCTCCTTTGATTT

Product: hypothetical protein

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MNILSPHDLELIIKLTLKINVILKSFFKSIQLQLVDFKLEFGYDFRNNILLADEISPDNCRLWDLNQKNDTIVSLDKDRF
RNDLGGLIEAYTEIHRRMNDFLLPN

Sequences:

>Translated_105_residues
MNILSPHDLELIIKLTLKINVILKSFFKSIQLQLVDFKLEFGYDFRNNILLADEISPDNCRLWDLNQKNDTIVSLDKDRF
RNDLGGLIEAYTEIHRRMNDFLLPN
>Mature_105_residues
MNILSPHDLELIIKLTLKINVILKSFFKSIQLQLVDFKLEFGYDFRNNILLADEISPDNCRLWDLNQKNDTIVSLDKDRF
RNDLGGLIEAYTEIHRRMNDFLLPN

Specific function: De novo purine biosynthesis; seventh step. [C]

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1788820, Length=96, Percent_Identity=47.9166666666667, Blast_Score=89, Evalue=6e-20,

Paralogues:

None

Copy number: 1680 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 13,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 12395; Mature: 12395

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILSPHDLELIIKLTLKINVILKSFFKSIQLQLVDFKLEFGYDFRNNILLADEISPDNC
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCCEEEEECCCCCCC
RLWDLNQKNDTIVSLDKDRFRNDLGGLIEAYTEIHRRMNDFLLPN
EEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNILSPHDLELIIKLTLKINVILKSFFKSIQLQLVDFKLEFGYDFRNNILLADEISPDNC
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCCCEEEEECCCCCCC
RLWDLNQKNDTIVSLDKDRFRNDLGGLIEAYTEIHRRMNDFLLPN
EEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]