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The map label for this gene is lpxA [H]

Identifier: 123969067

GI number: 123969067

Start: 1314893

End: 1315735

Strand: Reverse

Name: lpxA [H]

Synonym: A9601_15351

Alternate gene names: 123969067

Gene position: 1315735-1314893 (Counterclockwise)

Preceding gene: 123969068

Following gene: 123969066

Centisome position: 78.79

GC content: 33.57

Gene sequence:

>843_bases
ATGGAAAATAAAAATACTGAATCAAAGTCAATCTTTAGTGGTGTTAAAATTCACCCAAACGCTTTTGTTGATCCAAAGGC
AGAACTGCATGATGGGGTCATTATCGCTCAAGGAGCTATTATCGGTCCTGATGTGACTATTGGGAAAGGAACGGAGATAG
GACCGAATGCTGTTATTACTGGAAGAACTAAAATTGGAATAAACAATAAAGTTTTCCCTAATGTGTTTATAGGACTTGAT
CCCCAAGATCTTAAATATAAGGGGGCATTTACCGAAGTAATCATTGGAGATAATAATACTTTTAGAGAATGCGTAACTAT
AAATAAGGCAACTGATGAAGGAGAGAAAACTATTATTGGTAATAATAATTTGTTAATGGCTTACTCCCACATTGGCCATA
ATTGTGAACTTGCAAATGGGATAGTTTTATCAAATAGTGTTCAAGTTGCAGGCCATGTAAAGATTGAAGAAAAAGCTATT
ATTGGTGGCTGTTTAGGTATCCACCAATTTGTACATATTGGATATTTGGCAATGATTGGAGGAATGACAAGAGTAGATAG
GGATGTACCTCCTTTTTGTTTGGCAGAAGGACATCCAGGAAGATTAAGAGGTTTGAATAGGATTGGAATTAAAAGAAGTG
GTTTGATGGAAAACAAAGATTTTGATTTTAAATTACTTCAAAGTACTTGGAATCTTCTTTTTAAATCTAGCGATACTATT
ACAAATTCATTAGAAAAAGCCATGAACAGAGAATTAGATCTTTCATCTTCAAAATTATGTAATTTTTTAAAAGAGTCAAT
ATCTAAAGAAAGACGAGGACCAATGCCAGTAGTGAATTTATGA

Upstream 100 bases:

>100_bases
ATTAAAAGACAAAGATTTGGCAAAGTTAAAGGTGAGGCTCATGTTGATGGGAAGTTGGTTTGTTCTGGAGAATTAATGTT
CTCATTAGTCGACTAAGAAA

Downstream 100 bases:

>100_bases
ATAAAAAGATATTTATAAGTACTGGAGAAGTATCTGGTGATTTGCACGGAAGTTTGTTATCAAAAGCATTATTAGAGGAA
GCTAAAAAGAAATTCATAGA

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MENKNTESKSIFSGVKIHPNAFVDPKAELHDGVIIAQGAIIGPDVTIGKGTEIGPNAVITGRTKIGINNKVFPNVFIGLD
PQDLKYKGAFTEVIIGDNNTFRECVTINKATDEGEKTIIGNNNLLMAYSHIGHNCELANGIVLSNSVQVAGHVKIEEKAI
IGGCLGIHQFVHIGYLAMIGGMTRVDRDVPPFCLAEGHPGRLRGLNRIGIKRSGLMENKDFDFKLLQSTWNLLFKSSDTI
TNSLEKAMNRELDLSSSKLCNFLKESISKERRGPMPVVNL

Sequences:

>Translated_280_residues
MENKNTESKSIFSGVKIHPNAFVDPKAELHDGVIIAQGAIIGPDVTIGKGTEIGPNAVITGRTKIGINNKVFPNVFIGLD
PQDLKYKGAFTEVIIGDNNTFRECVTINKATDEGEKTIIGNNNLLMAYSHIGHNCELANGIVLSNSVQVAGHVKIEEKAI
IGGCLGIHQFVHIGYLAMIGGMTRVDRDVPPFCLAEGHPGRLRGLNRIGIKRSGLMENKDFDFKLLQSTWNLLFKSSDTI
TNSLEKAMNRELDLSSSKLCNFLKESISKERRGPMPVVNL
>Mature_280_residues
MENKNTESKSIFSGVKIHPNAFVDPKAELHDGVIIAQGAIIGPDVTIGKGTEIGPNAVITGRTKIGINNKVFPNVFIGLD
PQDLKYKGAFTEVIIGDNNTFRECVTINKATDEGEKTIIGNNNLLMAYSHIGHNCELANGIVLSNSVQVAGHVKIEEKAI
IGGCLGIHQFVHIGYLAMIGGMTRVDRDVPPFCLAEGHPGRLRGLNRIGIKRSGLMENKDFDFKLLQSTWNLLFKSSDTI
TNSLEKAMNRELDLSSSKLCNFLKESISKERRGPMPVVNL

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=225, Percent_Identity=39.1111111111111, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1786376, Length=225, Percent_Identity=29.7777777777778, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 30553; Mature: 30553

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKNTESKSIFSGVKIHPNAFVDPKAELHDGVIIAQGAIIGPDVTIGKGTEIGPNAVIT
CCCCCCCCHHHHCCEEECCCCCCCCCHHHCCCEEEECCEEECCCEEECCCCCCCCCCEEE
GRTKIGINNKVFPNVFIGLDPQDLKYKGAFTEVIIGDNNTFRECVTINKATDEGEKTIIG
CCEEECCCCCCCCEEEEECCCCCCEECCCEEEEEECCCCCEEEEEEEECCCCCCCEEEEC
NNNLLMAYSHIGHNCELANGIVLSNSVQVAGHVKIEEKAIIGGCLGIHQFVHIGYLAMIG
CCCEEEEEECCCCCCEECCCEEEECCEEEEEEEEEECCEEHHHHHHHHHHHHHHHHHHHC
GMTRVDRDVPPFCLAEGHPGRLRGLNRIGIKRSGLMENKDFDFKLLQSTWNLLFKSSDTI
CHHHHCCCCCCEEEECCCCHHHCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
TNSLEKAMNRELDLSSSKLCNFLKESISKERRGPMPVVNL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MENKNTESKSIFSGVKIHPNAFVDPKAELHDGVIIAQGAIIGPDVTIGKGTEIGPNAVIT
CCCCCCCCHHHHCCEEECCCCCCCCCHHHCCCEEEECCEEECCCEEECCCCCCCCCCEEE
GRTKIGINNKVFPNVFIGLDPQDLKYKGAFTEVIIGDNNTFRECVTINKATDEGEKTIIG
CCEEECCCCCCCCEEEEECCCCCCEECCCEEEEEECCCCCEEEEEEEECCCCCCCEEEEC
NNNLLMAYSHIGHNCELANGIVLSNSVQVAGHVKIEEKAIIGGCLGIHQFVHIGYLAMIG
CCCEEEEEECCCCCCEECCCEEEECCEEEEEEEEEECCEEHHHHHHHHHHHHHHHHHHHC
GMTRVDRDVPPFCLAEGHPGRLRGLNRIGIKRSGLMENKDFDFKLLQSTWNLLFKSSDTI
CHHHHCCCCCCEEEECCCCHHHCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
TNSLEKAMNRELDLSSSKLCNFLKESISKERRGPMPVVNL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA