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The map label for this gene is argD [H]

Identifier: 123969032

GI number: 123969032

Start: 1282642

End: 1283817

Strand: Direct

Name: argD [H]

Synonym: A9601_15001

Alternate gene names: 123969032

Gene position: 1282642-1283817 (Clockwise)

Preceding gene: 123969031

Following gene: 123969033

Centisome position: 76.81

GC content: 33.67

Gene sequence:

>1176_bases
ATGAATACCTATAGTCGATTCGATATATCTTTCAAAAAAGGAAAAGGTTGTTGGTTATGGGACAAATCAGGTAAAAAGTA
TCTTGATGCAGTCGCTGGTATAGCGACTTGCAGTCTTGGACATAGCGATAGAGTTTTAAGAAGAAGGCTATCAAGTCAAC
TAAAAAAGATTCAGCACATTTCCAATCTCTACAACATTGAAGAACAAGAACAATTAAGCAGAACTTTAACGAATATGAGT
TGTGCCAAAAGCGTCTTCTTCTGCAACAGTGGTGCAGAAGCAAATGAATCAGCAATTAAATTAATTAAAAAATATGGTAA
TACAACAAATAAAGGTAAAGAATCAATTATTCTCGCAGCAGAATCTAGCTTTCATGGAAGAACGCTGGCAGCCTTGAGTG
CTACTGGACAGCCCAAATACCAAAAAGGTTTCGAACCAATGATTCAAGGGTTCAAATTTTTTAAATTTAACAATTTTGAT
TCTGTAAAAAAATTATTTGAAGAGTGTGAAAATAATGACCAAAAGATTTCCGGCGTTTTAGTTGAACCAATACAAGGAGA
AGGTGGCGTAATTCCAGGAAGTAAAATATTTTTCAAAGGCCTTAGAGATATATGTAATAGACATAATTCTCTTCTAATTT
TAGATGAGGTCCAAAGTGGAGTAGGTAGAACTGGAAAAATGTGGGGTTATGAGAATTTAGGAATAGAACCTGATGGATTC
ACCCTTGCTAAAGGATTAGGAGGAGGTCATGCAATTGGAGCATTATTAGTAAAAGAAAAAGCCAATATTTTTACTCCAGG
AGATCATGCAAGCACTTTTGGGGGAAACCCTTTCGCCTGCAAAGCTGCTCTAACTGTATTAGAAGAAATAAATAGAAGAA
ATCTTATTAATAATGTTTATCTAAGAGGGGAACAATTAAGTGCTGGATTTGAAGAATTGTCAAAAAAATTTCCAAATATT
ATTAGCGAAAAAAGAGGTTTAGGTTTAATACAAGGTCTTGTGATCAATGATGATTATGCTGAAGCAAAAAAAATTACATT
AAAAGCTTTTGATAAAGGATTACTGGTAGTTCCTGCAGGAGGAAACGTCGTAAGAATTGTCCCACCATTAGTTATATCTC
GAAGAGAAATTAATATTCTTTTGAATAAGCTAAATTCAATTTTTGAAGAGTTATAA

Upstream 100 bases:

>100_bases
TTTCAAAAGCCTTGGGAGCGTGGTGGAATTGGTAGACGCACCGCACTCAAAATGCGGCACCTTCGGGTATGTCGGTTCAA
GTCCGACCGCTCCCACTTTG

Downstream 100 bases:

>100_bases
CAATTTAAATTTTGAAAAATGCAAATTTAAAAATTTTTGAATTATTATCTCCTAAATACGAAAGGGATAATATCAAATTA
GGTTTATCAAGAATTAAAAA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MNTYSRFDISFKKGKGCWLWDKSGKKYLDAVAGIATCSLGHSDRVLRRRLSSQLKKIQHISNLYNIEEQEQLSRTLTNMS
CAKSVFFCNSGAEANESAIKLIKKYGNTTNKGKESIILAAESSFHGRTLAALSATGQPKYQKGFEPMIQGFKFFKFNNFD
SVKKLFEECENNDQKISGVLVEPIQGEGGVIPGSKIFFKGLRDICNRHNSLLILDEVQSGVGRTGKMWGYENLGIEPDGF
TLAKGLGGGHAIGALLVKEKANIFTPGDHASTFGGNPFACKAALTVLEEINRRNLINNVYLRGEQLSAGFEELSKKFPNI
ISEKRGLGLIQGLVINDDYAEAKKITLKAFDKGLLVVPAGGNVVRIVPPLVISRREINILLNKLNSIFEEL

Sequences:

>Translated_391_residues
MNTYSRFDISFKKGKGCWLWDKSGKKYLDAVAGIATCSLGHSDRVLRRRLSSQLKKIQHISNLYNIEEQEQLSRTLTNMS
CAKSVFFCNSGAEANESAIKLIKKYGNTTNKGKESIILAAESSFHGRTLAALSATGQPKYQKGFEPMIQGFKFFKFNNFD
SVKKLFEECENNDQKISGVLVEPIQGEGGVIPGSKIFFKGLRDICNRHNSLLILDEVQSGVGRTGKMWGYENLGIEPDGF
TLAKGLGGGHAIGALLVKEKANIFTPGDHASTFGGNPFACKAALTVLEEINRRNLINNVYLRGEQLSAGFEELSKKFPNI
ISEKRGLGLIQGLVINDDYAEAKKITLKAFDKGLLVVPAGGNVVRIVPPLVISRREINILLNKLNSIFEEL
>Mature_391_residues
MNTYSRFDISFKKGKGCWLWDKSGKKYLDAVAGIATCSLGHSDRVLRRRLSSQLKKIQHISNLYNIEEQEQLSRTLTNMS
CAKSVFFCNSGAEANESAIKLIKKYGNTTNKGKESIILAAESSFHGRTLAALSATGQPKYQKGFEPMIQGFKFFKFNNFD
SVKKLFEECENNDQKISGVLVEPIQGEGGVIPGSKIFFKGLRDICNRHNSLLILDEVQSGVGRTGKMWGYENLGIEPDGF
TLAKGLGGGHAIGALLVKEKANIFTPGDHASTFGGNPFACKAALTVLEEINRRNLINNVYLRGEQLSAGFEELSKKFPNI
ISEKRGLGLIQGLVINDDYAEAKKITLKAFDKGLLVVPAGGNVVRIVPPLVISRREINILLNKLNSIFEEL

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=383, Percent_Identity=33.1592689295039, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI284507298, Length=296, Percent_Identity=36.1486486486487, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI13994255, Length=437, Percent_Identity=25.858123569794, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI37574042, Length=409, Percent_Identity=27.1393643031785, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI226442705, Length=412, Percent_Identity=26.6990291262136, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI188536080, Length=440, Percent_Identity=26.1363636363636, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI38679950, Length=440, Percent_Identity=26.1363636363636, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI38679946, Length=440, Percent_Identity=26.1363636363636, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI226442709, Length=358, Percent_Identity=28.2122905027933, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI24119277, Length=418, Percent_Identity=22.7272727272727, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1788044, Length=381, Percent_Identity=43.5695538057743, Blast_Score=318, Evalue=4e-88,
Organism=Escherichia coli, GI1789759, Length=368, Percent_Identity=37.5, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI145693181, Length=387, Percent_Identity=34.1085271317829, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1789016, Length=403, Percent_Identity=30.0248138957816, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1787560, Length=406, Percent_Identity=29.064039408867, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1786349, Length=331, Percent_Identity=27.190332326284, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786991, Length=408, Percent_Identity=25.9803921568627, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=380, Percent_Identity=33.9473684210526, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI25144274, Length=269, Percent_Identity=37.1747211895911, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI32564660, Length=430, Percent_Identity=29.3023255813954, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=412, Percent_Identity=25.7281553398058, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=439, Percent_Identity=27.3348519362187, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71981843, Length=166, Percent_Identity=29.5180722891566, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=384, Percent_Identity=40.3645833333333, Blast_Score=252, Evalue=7e-68,
Organism=Saccharomyces cerevisiae, GI6323470, Length=393, Percent_Identity=32.0610687022901, Blast_Score=209, Evalue=7e-55,
Organism=Saccharomyces cerevisiae, GI6321456, Length=433, Percent_Identity=26.7898383371824, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6324386, Length=437, Percent_Identity=23.7986270022883, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI21357415, Length=394, Percent_Identity=31.7258883248731, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI161085790, Length=419, Percent_Identity=28.1622911694511, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28574759, Length=414, Percent_Identity=28.5024154589372, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI281366494, Length=439, Percent_Identity=27.7904328018223, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24667139, Length=439, Percent_Identity=27.7904328018223, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24667143, Length=439, Percent_Identity=27.7904328018223, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21356575, Length=414, Percent_Identity=26.5700483091787, Blast_Score=122, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43072; Mature: 43072

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTYSRFDISFKKGKGCWLWDKSGKKYLDAVAGIATCSLGHSDRVLRRRLSSQLKKIQHI
CCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
SNLYNIEEQEQLSRTLTNMSCAKSVFFCNSGAEANESAIKLIKKYGNTTNKGKESIILAA
HHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEE
ESSFHGRTLAALSATGQPKYQKGFEPMIQGFKFFKFNNFDSVKKLFEECENNDQKISGVL
CCCCCCCEEEEEECCCCCHHHCCHHHHHCCEEEEEECCHHHHHHHHHHHCCCCCEEEEEE
VEPIQGEGGVIPGSKIFFKGLRDICNRHNSLLILDEVQSGVGRTGKMWGYENLGIEPDGF
EECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCCC
TLAKGLGGGHAIGALLVKEKANIFTPGDHASTFGGNPFACKAALTVLEEINRRNLINNVY
EEECCCCCCHHHHHHHEECCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHE
LRGEQLSAGFEELSKKFPNIISEKRGLGLIQGLVINDDYAEAKKITLKAFDKGLLVVPAG
ECCHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHEEHEECCCCEEEEECC
GNVVRIVPPLVISRREINILLNKLNSIFEEL
CCEEEECCCHHHCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNTYSRFDISFKKGKGCWLWDKSGKKYLDAVAGIATCSLGHSDRVLRRRLSSQLKKIQHI
CCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
SNLYNIEEQEQLSRTLTNMSCAKSVFFCNSGAEANESAIKLIKKYGNTTNKGKESIILAA
HHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEE
ESSFHGRTLAALSATGQPKYQKGFEPMIQGFKFFKFNNFDSVKKLFEECENNDQKISGVL
CCCCCCCEEEEEECCCCCHHHCCHHHHHCCEEEEEECCHHHHHHHHHHHCCCCCEEEEEE
VEPIQGEGGVIPGSKIFFKGLRDICNRHNSLLILDEVQSGVGRTGKMWGYENLGIEPDGF
EECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCCC
TLAKGLGGGHAIGALLVKEKANIFTPGDHASTFGGNPFACKAALTVLEEINRRNLINNVY
EEECCCCCCHHHHHHHEECCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHE
LRGEQLSAGFEELSKKFPNIISEKRGLGLIQGLVINDDYAEAKKITLKAFDKGLLVVPAG
ECCHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHEEHEECCCCEEEEECC
GNVVRIVPPLVISRREINILLNKLNSIFEEL
CCEEEECCCHHHCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]