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The map label for this gene is cysS [H]

Identifier: 123968849

GI number: 123968849

Start: 1094309

End: 1095778

Strand: Direct

Name: cysS [H]

Synonym: A9601_13161

Alternate gene names: 123968849

Gene position: 1094309-1095778 (Clockwise)

Preceding gene: 123968848

Following gene: 123968850

Centisome position: 65.53

GC content: 31.63

Gene sequence:

>1470_bases
ATGATCAAACTTTTTAATACTTTAAGCAAAAAAGTTGAGGTTTTTAAGCCTATTGATGATGTAGTAAAAATTTATTGTTG
TGGGGTAACTGTTTATGATTTATGTCATCTTGGTCATGCCAGAAGTTATATCGCTTGGGATGTATTGAGAAGATTTTTAA
TTTACAGTGATTTCAAAGTGAAGTATGTTCAAAATTTTACAGATATTGATGACAAGATCTTAAAAAGAGCGAAAGAAGAA
AGCAGTTCAATGAAGGAAGTATCTGAAAAGAATATCATTGAGTTTCACAAAGATATGGATTCTTTAGGGATAATGCGTCC
GGATAGCATGCCAAGAGCAACGAATCATATATGCAATATCTGTTCCTTCATAACAATCCTTGAGGACAAAGGTTATGCAT
ACTCTAGGGATGGAGACGTTTATTATTCTGTTTTCAAAAATAAAAATTATGGAAAGCTAAGTAATCAAAATTTACAAGAA
CAAAATATCAATCAGCAAGGAAGAATGGTTAATGAGGAAAATAGTAAAAAACTTAATCCGCAAGATTTTGCGCTATGGAA
AAAAGCCAAAGATGATGAACCATTTTTTGATTCGCCATGGGGTAAAGGTAGGCCAGGATGGCATATTGAATGTTCGGCGA
TGGTTAAAGATGAATTAGGAGATACTATCGATATCCATTTAGGTGGTTCTGATTTGATTTTTCCACATCATGAGAATGAA
ATCGCCCAATCAGAAGCAGCCAATGGCAAAAAGCTAGCGAACTATTGGTTACACAATGGGATGGTCAATGTAAATGGACA
AAAGATGAGTAAATCCCTTAAAAATTTTAAAACTATCAGAGAGCTAATTAAGTCAGGTATTAGCCCTATGACTTTGCGAT
ATTTTGTTATGACTGTGAATTATAGAAAACCACTTGATTTTACTGAAGAAGCTTTAAGGAGTGCTTCAGAAGCTTGGAAA
AACATTAATGTAGCACTTTCTTTTATGGACCTTACAAAAGGTGCTTTTATATCTATTGATAAAAATGAATCTATCGAAGA
AAAATATAAAGAGAAAATAAGTTTTGAATTATCTCAAAAAAAGCTTAAATTTTCTGAGGCTCTTGGAAATGACCTTAACA
CAGCAGGTGCTATTGCAATTATTTACGATTTAGCGAAACCCTTAAAAAACTTTTTAAACCAATTTCAAAGGGTTGAAGGT
TTTACAGTAGAACTAAATGAAAAATTCTTTCTACTTGAAAATTTTAAAACTCTTGAAAAGTTAACTGAGGTACTTGGTCT
TAAAAAAGAGGTTTTAGTAAAAGAAAGTAAAATAAAAGAAGAAGAAATATCATCGCTCATTAATGAAAGATTGAAAGCAA
AAATGGAAAAGAATTATGCGAAGGCGGATGAAATCAGGAATTTGTTAAAAGAAAAAGGTATTGAACTTATTGATCAATCA
AAGGAAATAACAACATGGATAAGGGTCTAA

Upstream 100 bases:

>100_bases
GGAAGATTGTGTAAAATTAAATGTGCCTCTTTTAGTTGATGTTGGAATTGGAGACAATTGGATGGAGACAAAATAAACCT
TATGAAATACTTATTTTAAG

Downstream 100 bases:

>100_bases
ATTTTAAGAAAAAAACCAATTTGAAATTTTTGTTTTTTAAATACACCTTTAAATGGGAAGATATTAGAAATATCAGAGAA
AATTGAAATACATTACTGTG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MIKLFNTLSKKVEVFKPIDDVVKIYCCGVTVYDLCHLGHARSYIAWDVLRRFLIYSDFKVKYVQNFTDIDDKILKRAKEE
SSSMKEVSEKNIIEFHKDMDSLGIMRPDSMPRATNHICNICSFITILEDKGYAYSRDGDVYYSVFKNKNYGKLSNQNLQE
QNINQQGRMVNEENSKKLNPQDFALWKKAKDDEPFFDSPWGKGRPGWHIECSAMVKDELGDTIDIHLGGSDLIFPHHENE
IAQSEAANGKKLANYWLHNGMVNVNGQKMSKSLKNFKTIRELIKSGISPMTLRYFVMTVNYRKPLDFTEEALRSASEAWK
NINVALSFMDLTKGAFISIDKNESIEEKYKEKISFELSQKKLKFSEALGNDLNTAGAIAIIYDLAKPLKNFLNQFQRVEG
FTVELNEKFFLLENFKTLEKLTEVLGLKKEVLVKESKIKEEEISSLINERLKAKMEKNYAKADEIRNLLKEKGIELIDQS
KEITTWIRV

Sequences:

>Translated_489_residues
MIKLFNTLSKKVEVFKPIDDVVKIYCCGVTVYDLCHLGHARSYIAWDVLRRFLIYSDFKVKYVQNFTDIDDKILKRAKEE
SSSMKEVSEKNIIEFHKDMDSLGIMRPDSMPRATNHICNICSFITILEDKGYAYSRDGDVYYSVFKNKNYGKLSNQNLQE
QNINQQGRMVNEENSKKLNPQDFALWKKAKDDEPFFDSPWGKGRPGWHIECSAMVKDELGDTIDIHLGGSDLIFPHHENE
IAQSEAANGKKLANYWLHNGMVNVNGQKMSKSLKNFKTIRELIKSGISPMTLRYFVMTVNYRKPLDFTEEALRSASEAWK
NINVALSFMDLTKGAFISIDKNESIEEKYKEKISFELSQKKLKFSEALGNDLNTAGAIAIIYDLAKPLKNFLNQFQRVEG
FTVELNEKFFLLENFKTLEKLTEVLGLKKEVLVKESKIKEEEISSLINERLKAKMEKNYAKADEIRNLLKEKGIELIDQS
KEITTWIRV
>Mature_489_residues
MIKLFNTLSKKVEVFKPIDDVVKIYCCGVTVYDLCHLGHARSYIAWDVLRRFLIYSDFKVKYVQNFTDIDDKILKRAKEE
SSSMKEVSEKNIIEFHKDMDSLGIMRPDSMPRATNHICNICSFITILEDKGYAYSRDGDVYYSVFKNKNYGKLSNQNLQE
QNINQQGRMVNEENSKKLNPQDFALWKKAKDDEPFFDSPWGKGRPGWHIECSAMVKDELGDTIDIHLGGSDLIFPHHENE
IAQSEAANGKKLANYWLHNGMVNVNGQKMSKSLKNFKTIRELIKSGISPMTLRYFVMTVNYRKPLDFTEEALRSASEAWK
NINVALSFMDLTKGAFISIDKNESIEEKYKEKISFELSQKKLKFSEALGNDLNTAGAIAIIYDLAKPLKNFLNQFQRVEG
FTVELNEKFFLLENFKTLEKLTEVLGLKKEVLVKESKIKEEEISSLINERLKAKMEKNYAKADEIRNLLKEKGIELIDQS
KEITTWIRV

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=515, Percent_Identity=32.621359223301, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI10835051, Length=240, Percent_Identity=41.25, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI62240992, Length=240, Percent_Identity=41.25, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI21269877, Length=240, Percent_Identity=41.25, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI303304987, Length=240, Percent_Identity=41.25, Blast_Score=191, Evalue=2e-48,
Organism=Escherichia coli, GI1786737, Length=497, Percent_Identity=42.2535211267606, Blast_Score=363, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17509795, Length=307, Percent_Identity=35.5048859934853, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17509797, Length=307, Percent_Identity=35.5048859934853, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324082, Length=229, Percent_Identity=44.5414847161572, Blast_Score=194, Evalue=3e-50,
Organism=Drosophila melanogaster, GI19922218, Length=521, Percent_Identity=33.0134357005758, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI19922364, Length=307, Percent_Identity=38.1107491856677, Blast_Score=199, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 56516; Mature: 56516

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLFNTLSKKVEVFKPIDDVVKIYCCGVTVYDLCHLGHARSYIAWDVLRRFLIYSDFKV
CCCHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHH
KYVQNFTDIDDKILKRAKEESSSMKEVSEKNIIEFHKDMDSLGIMRPDSMPRATNHICNI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
CSFITILEDKGYAYSRDGDVYYSVFKNKNYGKLSNQNLQEQNINQQGRMVNEENSKKLNP
HHHHHHHCCCCCEECCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
QDFALWKKAKDDEPFFDSPWGKGRPGWHIECSAMVKDELGDTIDIHLGGSDLIFPHHENE
HHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCEEEEEECCCCEECCCCCCH
IAQSEAANGKKLANYWLHNGMVNVNGQKMSKSLKNFKTIRELIKSGISPMTLRYFVMTVN
HHHHHCCCCHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEC
YRKPLDFTEEALRSASEAWKNINVALSFMDLTKGAFISIDKNESIEEKYKEKISFELSQK
CCCCCCHHHHHHHHHHHHHHCHHHEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHH
KLKFSEALGNDLNTAGAIAIIYDLAKPLKNFLNQFQRVEGFTVELNEKFFLLENFKTLEK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEHHHHHHHHH
LTEVLGLKKEVLVKESKIKEEEISSLINERLKAKMEKNYAKADEIRNLLKEKGIELIDQS
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
KEITTWIRV
CHHHHHCCC
>Mature Secondary Structure
MIKLFNTLSKKVEVFKPIDDVVKIYCCGVTVYDLCHLGHARSYIAWDVLRRFLIYSDFKV
CCCHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHH
KYVQNFTDIDDKILKRAKEESSSMKEVSEKNIIEFHKDMDSLGIMRPDSMPRATNHICNI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
CSFITILEDKGYAYSRDGDVYYSVFKNKNYGKLSNQNLQEQNINQQGRMVNEENSKKLNP
HHHHHHHCCCCCEECCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
QDFALWKKAKDDEPFFDSPWGKGRPGWHIECSAMVKDELGDTIDIHLGGSDLIFPHHENE
HHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCEEEEEECCCCEECCCCCCH
IAQSEAANGKKLANYWLHNGMVNVNGQKMSKSLKNFKTIRELIKSGISPMTLRYFVMTVN
HHHHHCCCCHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEC
YRKPLDFTEEALRSASEAWKNINVALSFMDLTKGAFISIDKNESIEEKYKEKISFELSQK
CCCCCCHHHHHHHHHHHHHHCHHHEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHH
KLKFSEALGNDLNTAGAIAIIYDLAKPLKNFLNQFQRVEGFTVELNEKFFLLENFKTLEK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEHHHHHHHHH
LTEVLGLKKEVLVKESKIKEEEISSLINERLKAKMEKNYAKADEIRNLLKEKGIELIDQS
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
KEITTWIRV
CHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA