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The map label for this gene is ruvC [H]

Identifier: 123968692

GI number: 123968692

Start: 973822

End: 974295

Strand: Reverse

Name: ruvC [H]

Synonym: A9601_11591

Alternate gene names: 123968692

Gene position: 974295-973822 (Counterclockwise)

Preceding gene: 123968693

Following gene: 123968691

Centisome position: 58.35

GC content: 34.39

Gene sequence:

>474_bases
GTGAGAATAATTGGGATTGACCCCGGATTAGCTAGAGTTGGTTATGGAATAATTGAGATAGAAAATGAAAGAAAGATATT
ATTAGATTGTGGCGTTATTGAAACAGGTAAAGATAAAAAAGAAGAAGATAGACTTTATGAGATATTCCAAGATCTTAATG
AATTAATAAATCATTGGAAACCAACTGTAGCGGCAGTAGAAAAATTTTTCTTTTACAGGTCAAGTACTACCATTAGTGTG
GTGCAGGCCAGAGGCGTGATTATGATGGTATTGGCCTCTAAAAAAATTCATGTTAGTGAGTATTCACCCGCTAAGATAAA
ATTAACAATTGCTGGATCAGGAAAGGCATCTAAGAAAGATATTCTTGATGCTGTTATGTACAACTTAGATCTTGACAAAC
CTCCAAAACCTGATGATTCAGCAGATGCATTAGCTATAGCACTTACAAAACTAAATGAGGATGGCTTTAACTAA

Upstream 100 bases:

>100_bases
ATTCAGGAGAAAGGGTTATTCAAGCTTTTTGTAAAGTATTTGATTTAGATGAAAAAGAAAATTTATCAAAATTTCAATTA
TCTGCTGAAGCTTAATAACA

Downstream 100 bases:

>100_bases
AAAATTTAATATGACTATCTTTGAAAATAAGAAATTGGAGAGGGATAAGTTTAGAAAACTAAGAGATGGGATTTCTCTTA
ATCAAAGAGAAAATGTAGAA

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MRIIGIDPGLARVGYGIIEIENERKILLDCGVIETGKDKKEEDRLYEIFQDLNELINHWKPTVAAVEKFFFYRSSTTISV
VQARGVIMMVLASKKIHVSEYSPAKIKLTIAGSGKASKKDILDAVMYNLDLDKPPKPDDSADALAIALTKLNEDGFN

Sequences:

>Translated_157_residues
MRIIGIDPGLARVGYGIIEIENERKILLDCGVIETGKDKKEEDRLYEIFQDLNELINHWKPTVAAVEKFFFYRSSTTISV
VQARGVIMMVLASKKIHVSEYSPAKIKLTIAGSGKASKKDILDAVMYNLDLDKPPKPDDSADALAIALTKLNEDGFN
>Mature_157_residues
MRIIGIDPGLARVGYGIIEIENERKILLDCGVIETGKDKKEEDRLYEIFQDLNELINHWKPTVAAVEKFFFYRSSTTISV
VQARGVIMMVLASKKIHVSEYSPAKIKLTIAGSGKASKKDILDAVMYNLDLDKPPKPDDSADALAIALTKLNEDGFN

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=135, Percent_Identity=31.1111111111111, Blast_Score=68, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 17470; Mature: 17470

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIGIDPGLARVGYGIIEIENERKILLDCGVIETGKDKKEEDRLYEIFQDLNELINHWK
CEEEECCCCHHHHCCEEEEECCCCEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHCC
PTVAAVEKFFFYRSSTTISVVQARGVIMMVLASKKIHVSEYSPAKIKLTIAGSGKASKKD
HHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCEEEECCCCCCEEEEEEECCCCCCHHH
ILDAVMYNLDLDKPPKPDDSADALAIALTKLNEDGFN
HHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MRIIGIDPGLARVGYGIIEIENERKILLDCGVIETGKDKKEEDRLYEIFQDLNELINHWK
CEEEECCCCHHHHCCEEEEECCCCEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHCC
PTVAAVEKFFFYRSSTTISVVQARGVIMMVLASKKIHVSEYSPAKIKLTIAGSGKASKKD
HHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCEEEECCCCCCEEEEEEECCCCCCHHH
ILDAVMYNLDLDKPPKPDDSADALAIALTKLNEDGFN
HHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA