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The map label for this gene is htpG [H]

Identifier: 123968493

GI number: 123968493

Start: 825513

End: 827417

Strand: Reverse

Name: htpG [H]

Synonym: A9601_09601

Alternate gene names: 123968493

Gene position: 827417-825513 (Counterclockwise)

Preceding gene: 123968494

Following gene: 123968492

Centisome position: 49.55

GC content: 30.97

Gene sequence:

>1905_bases
ATGGAAAAAGGCGAAATTCGTATTAATACCGAAAATATTTTCCCAATTATCAAGAAGGCAGTATATTCTGACCATGAAAT
CTTTTTAAGAGAACTTGTTAGTAATGGTGTTGACGCAATTAGTAAAAGGAGAATGGCCTCTATGGCTGGTGATTGCGAGA
ATACTGAGGAGGCTCAAGTAAAAATAACAATTAACCGTGAAAAAAGTACGTTAACAATTTCCGATAATGGAATTGGAATG
AATGATGAAGAAATTAAGAAGTACATAAATCAAGTTGCATTTTCTAGTGCTGAAGAATTCCTAACAAAATACAAAAAAGA
TAATGATGAATTCATAGGTCATTTTGGACTAGGTTTTTATTCAAGTTTCATGGTGGCAGATAGAGTTGATATATTAACTA
AGTCGGCAATTGGGGAATCAAAAGCTTTCAAATGGTCTTGTGATGGATCGCCAAATTTCACGTTAGAGGAATCTGAAAGA
GAAACAATTGGTACAGATGTTATTCTTCACCTACTTGAAGAAGAAAAAGAGTTTATCGAGCCTGAAAGAATTAAATCACT
AATAAAAAAATATTGTGATTTTATGCCAATAGATGTCTTATTAGAAGGAGAGACAATTAATAAGAAAAATCCTCCCTGGA
GAAAACAACCTAGTGAATTAAAAGATGAAGATTATATTGAGTTATATAAATACCTTTATCCTTTCCAGGGAGATCCACTG
TTATGGATTCATCTAAATACAGATTACCCATATGACATACAAGGCATTTTGTATTTTCCAAAGTTGTCAGGTAGAGCTGA
TTGGGAAAAGGGAGAAATAAAACTGTTTTGCAATCAAGTATTCGTAAGCGATTCAATTAAAGAGATAGTACCAAAATACC
TTTTACCTTTAAGAGGAGTTATTGACTCTACAGATATACCTCTAAATGTTAGTAGAAGTGCATTACAAACAGATAGAAAA
GTAAGGTCTATATCATCATTTATCTCAAAAAAAATCGCTAATAAACTGAAGGATTTGATAAAAAATTCTCCAGAATTTTA
TGCAGAAATTTGGGATTCAATCTCTGCTTTTATTAAAATTGGTGCTATCGAAGATGAAAAATTTGCTGATTTAGTTAATA
ACAGTATAATTTTCGAAACAATTTTAAACTCAGAGAAAGACGTAACTAAAGATATTGAAAATAAATCCCTGATCAAGTCC
AATGATAAATATTTCACAACTCTCGCAAATTACAAAGAGCGAAATAAATTAACTGATTCTAAAAAAATAATTTATTGTTC
AGATCTGATTGCACAGTCTAGTGCATTAAATATCTGTTTATCTGATAATAAAGAAGTTATTAAATCAGATCCCTTAATTG
ACGCACAATTTCTTCCATGGTTGGAAAGTAAAAATGAAGATTATCAATTCCAAAGAGTAGATTCAGAAATAAATGAACTA
GAAGATAAAGAATCTAAAGAAATTGTAGATAAGGATGGCAAATCAAATACAGATAATCTTAGAGATACGATAGTTAAAGC
CCTTAAAAATGAGAAAGTAACAGTTAAAGTGCAGTCACTTTCAAGTAAAGATGCTCCACCAGCGATGATCTTGCTTCCAG
AACAAATGAGAAGAATTAATGATATGGGTGCTTACATGGAACAAAAGATGCCTGGCTTACCTGAATATCATGTGCTCTTA
ATTAACAAAGAACATCCACTTATTGTTGGTCTTAATAAAATTACAGGCAACAAAATAATTATTGATGAAAAAGATCCTAT
TGAGAATCCATTAGCCTCTAAAATTGCTAATCATGTCTACGATATGGCTAAGCTTTCCGTTGGTGGATTAGATCAAGAAC
AGATAATTAATTTACAAAATAATAATGCCGAATTAATTTCAGAACTACTAAATTCAACAAATTGA

Upstream 100 bases:

>100_bases
TTAAGTTTTAAAATTCAAATATTGTTCGGACAATACTCCTAATTAAACTTGATTAACAAGTTTTTAAGAAATATTATTTA
ATATGTTTGATTTTTTTTAA

Downstream 100 bases:

>100_bases
GTCATGTGTTAGAATTTTTAAAGATATAACTCAATTAATATGTCAAGAGCTTGCGAACTGACAGGTGCAAAAGCTAATAA
CGGAATGGCAGTGAGTCACT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNGVDAISKRRMASMAGDCENTEEAQVKITINREKSTLTISDNGIGM
NDEEIKKYINQVAFSSAEEFLTKYKKDNDEFIGHFGLGFYSSFMVADRVDILTKSAIGESKAFKWSCDGSPNFTLEESER
ETIGTDVILHLLEEEKEFIEPERIKSLIKKYCDFMPIDVLLEGETINKKNPPWRKQPSELKDEDYIELYKYLYPFQGDPL
LWIHLNTDYPYDIQGILYFPKLSGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGVIDSTDIPLNVSRSALQTDRK
VRSISSFISKKIANKLKDLIKNSPEFYAEIWDSISAFIKIGAIEDEKFADLVNNSIIFETILNSEKDVTKDIENKSLIKS
NDKYFTTLANYKERNKLTDSKKIIYCSDLIAQSSALNICLSDNKEVIKSDPLIDAQFLPWLESKNEDYQFQRVDSEINEL
EDKESKEIVDKDGKSNTDNLRDTIVKALKNEKVTVKVQSLSSKDAPPAMILLPEQMRRINDMGAYMEQKMPGLPEYHVLL
INKEHPLIVGLNKITGNKIIIDEKDPIENPLASKIANHVYDMAKLSVGGLDQEQIINLQNNNAELISELLNSTN

Sequences:

>Translated_634_residues
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNGVDAISKRRMASMAGDCENTEEAQVKITINREKSTLTISDNGIGM
NDEEIKKYINQVAFSSAEEFLTKYKKDNDEFIGHFGLGFYSSFMVADRVDILTKSAIGESKAFKWSCDGSPNFTLEESER
ETIGTDVILHLLEEEKEFIEPERIKSLIKKYCDFMPIDVLLEGETINKKNPPWRKQPSELKDEDYIELYKYLYPFQGDPL
LWIHLNTDYPYDIQGILYFPKLSGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGVIDSTDIPLNVSRSALQTDRK
VRSISSFISKKIANKLKDLIKNSPEFYAEIWDSISAFIKIGAIEDEKFADLVNNSIIFETILNSEKDVTKDIENKSLIKS
NDKYFTTLANYKERNKLTDSKKIIYCSDLIAQSSALNICLSDNKEVIKSDPLIDAQFLPWLESKNEDYQFQRVDSEINEL
EDKESKEIVDKDGKSNTDNLRDTIVKALKNEKVTVKVQSLSSKDAPPAMILLPEQMRRINDMGAYMEQKMPGLPEYHVLL
INKEHPLIVGLNKITGNKIIIDEKDPIENPLASKIANHVYDMAKLSVGGLDQEQIINLQNNNAELISELLNSTN
>Mature_634_residues
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNGVDAISKRRMASMAGDCENTEEAQVKITINREKSTLTISDNGIGM
NDEEIKKYINQVAFSSAEEFLTKYKKDNDEFIGHFGLGFYSSFMVADRVDILTKSAIGESKAFKWSCDGSPNFTLEESER
ETIGTDVILHLLEEEKEFIEPERIKSLIKKYCDFMPIDVLLEGETINKKNPPWRKQPSELKDEDYIELYKYLYPFQGDPL
LWIHLNTDYPYDIQGILYFPKLSGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGVIDSTDIPLNVSRSALQTDRK
VRSISSFISKKIANKLKDLIKNSPEFYAEIWDSISAFIKIGAIEDEKFADLVNNSIIFETILNSEKDVTKDIENKSLIKS
NDKYFTTLANYKERNKLTDSKKIIYCSDLIAQSSALNICLSDNKEVIKSDPLIDAQFLPWLESKNEDYQFQRVDSEINEL
EDKESKEIVDKDGKSNTDNLRDTIVKALKNEKVTVKVQSLSSKDAPPAMILLPEQMRRINDMGAYMEQKMPGLPEYHVLL
INKEHPLIVGLNKITGNKIIIDEKDPIENPLASKIANHVYDMAKLSVGGLDQEQIINLQNNNAELISELLNSTN

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=636, Percent_Identity=27.5157232704403, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI4507677, Length=652, Percent_Identity=28.0674846625767, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI153792590, Length=198, Percent_Identity=35.8585858585859, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI154146191, Length=198, Percent_Identity=35.8585858585859, Blast_Score=123, Evalue=7e-28,
Organism=Homo sapiens, GI20149594, Length=200, Percent_Identity=37, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1786679, Length=587, Percent_Identity=29.9829642248722, Blast_Score=235, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI115535205, Length=645, Percent_Identity=28.9922480620155, Blast_Score=245, Evalue=5e-65,
Organism=Caenorhabditis elegans, GI115535167, Length=431, Percent_Identity=32.0185614849188, Blast_Score=232, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17542208, Length=691, Percent_Identity=27.9305354558611, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17559162, Length=414, Percent_Identity=27.7777777777778, Blast_Score=174, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323840, Length=607, Percent_Identity=28.006589785832, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6325016, Length=216, Percent_Identity=35.6481481481481, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24586016, Length=662, Percent_Identity=28.8519637462236, Blast_Score=252, Evalue=6e-67,
Organism=Drosophila melanogaster, GI21357739, Length=690, Percent_Identity=27.2463768115942, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI17647529, Length=197, Percent_Identity=33.502538071066, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72462; Mature: 72462

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNGVDAISKRRMASMAGDCENTEEAQV
CCCCCEEEECHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEE
KITINREKSTLTISDNGIGMNDEEIKKYINQVAFSSAEEFLTKYKKDNDEFIGHFGLGFY
EEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHHHH
SSFMVADRVDILTKSAIGESKAFKWSCDGSPNFTLEESERETIGTDVILHLLEEEKEFIE
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCC
PERIKSLIKKYCDFMPIDVLLEGETINKKNPPWRKQPSELKDEDYIELYKYLYPFQGDPL
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCE
LWIHLNTDYPYDIQGILYFPKLSGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGV
EEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHC
IDSTDIPLNVSRSALQTDRKVRSISSFISKKIANKLKDLIKNSPEFYAEIWDSISAFIKI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEE
GAIEDEKFADLVNNSIIFETILNSEKDVTKDIENKSLIKSNDKYFTTLANYKERNKLTDS
CCCCCHHHHHHHCCCHHHHHHHCCCHHHHHHCCCCHHHCCCCCEEEHHHHHHHHHCCCCC
KKIIYCSDLIAQSSALNICLSDNKEVIKSDPLIDAQFLPWLESKNEDYQFQRVDSEINEL
CEEEEEHHHHHCCCCEEEEECCCCHHHHCCCCCCHHHCCHHCCCCCCCHHHHHHHHHHHH
EDKESKEIVDKDGKSNTDNLRDTIVKALKNEKVTVKVQSLSSKDAPPAMILLPEQMRRIN
CCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECHHHHHHHH
DMGAYMEQKMPGLPEYHVLLINKEHPLIVGLNKITGNKIIIDEKDPIENPLASKIANHVY
HHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHH
DMAKLSVGGLDQEQIINLQNNNAELISELLNSTN
HHHHHCCCCCCHHHEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNGVDAISKRRMASMAGDCENTEEAQV
CCCCCEEEECHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEE
KITINREKSTLTISDNGIGMNDEEIKKYINQVAFSSAEEFLTKYKKDNDEFIGHFGLGFY
EEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHHHH
SSFMVADRVDILTKSAIGESKAFKWSCDGSPNFTLEESERETIGTDVILHLLEEEKEFIE
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCC
PERIKSLIKKYCDFMPIDVLLEGETINKKNPPWRKQPSELKDEDYIELYKYLYPFQGDPL
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCE
LWIHLNTDYPYDIQGILYFPKLSGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGV
EEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHC
IDSTDIPLNVSRSALQTDRKVRSISSFISKKIANKLKDLIKNSPEFYAEIWDSISAFIKI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEE
GAIEDEKFADLVNNSIIFETILNSEKDVTKDIENKSLIKSNDKYFTTLANYKERNKLTDS
CCCCCHHHHHHHCCCHHHHHHHCCCHHHHHHCCCCHHHCCCCCEEEHHHHHHHHHCCCCC
KKIIYCSDLIAQSSALNICLSDNKEVIKSDPLIDAQFLPWLESKNEDYQFQRVDSEINEL
CEEEEEHHHHHCCCCEEEEECCCCHHHHCCCCCCHHHCCHHCCCCCCCHHHHHHHHHHHH
EDKESKEIVDKDGKSNTDNLRDTIVKALKNEKVTVKVQSLSSKDAPPAMILLPEQMRRIN
CCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECHHHHHHHH
DMGAYMEQKMPGLPEYHVLLINKEHPLIVGLNKITGNKIIIDEKDPIENPLASKIANHVY
HHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHH
DMAKLSVGGLDQEQIINLQNNNAELISELLNSTN
HHHHHCCCCCCHHHEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10722592 [H]