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The map label for this gene is lspA [H]

Identifier: 123968479

GI number: 123968479

Start: 814832

End: 815287

Strand: Reverse

Name: lspA [H]

Synonym: A9601_09461

Alternate gene names: 123968479

Gene position: 815287-814832 (Counterclockwise)

Preceding gene: 123968480

Following gene: 123968478

Centisome position: 48.82

GC content: 17.98

Gene sequence:

>456_bases
ATGGTTAATAAAATACAAACAAAATTATATTTTTTATCATTAAGTATTTTTATTGTTCTAATAGATCAATTTACAAAGTA
TTTAATATCTTATGAAAAATTATTTGTCAATAAAGATTTTCTTTTATTCAAATTAGACCTTGTAAAGAATTATGGGGCAG
CATTTAACATATTTAGTGGTAGTAGAATTTTTTTATCTTTAATAAGTATTATCTTTTCAATATTAATTATTTATTTAATA
TTTAGGAAAAATACCTTAAACATATTTGATTTATATGCTTATAGCTTTATACTTGGTGGAACTTTTGGTAATGGTATAGA
TAGAATATATAAAGGATTTGTGGTTGATTTTATAAATTTAAATATTATAAATTTTCCAGTATTTAATATTGCTGATATAT
CTATTAATATTGGTTTTATTTTTTTACTGTATAACTTATTTAAAAATAATAGATAA

Upstream 100 bases:

>100_bases
TAGGTAAATACTCATTAGGTAAGATTGGATATCATTTTTTAATGCTTTTTCCACTCTTATTACTTATAAAACCTATAGAA
CGAATAAAACATAATAAATA

Downstream 100 bases:

>100_bases
AATGAATCACTTGAAGTTAAAGTATATAAAGTATTTGGTCTTAATATTATTTCTATATATTTTATTTTCGATATTTGTAA
GAATAGTAAATATTTATACT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MVNKIQTKLYFLSLSIFIVLIDQFTKYLISYEKLFVNKDFLLFKLDLVKNYGAAFNIFSGSRIFLSLISIIFSILIIYLI
FRKNTLNIFDLYAYSFILGGTFGNGIDRIYKGFVVDFINLNIINFPVFNIADISINIGFIFLLYNLFKNNR

Sequences:

>Translated_151_residues
MVNKIQTKLYFLSLSIFIVLIDQFTKYLISYEKLFVNKDFLLFKLDLVKNYGAAFNIFSGSRIFLSLISIIFSILIIYLI
FRKNTLNIFDLYAYSFILGGTFGNGIDRIYKGFVVDFINLNIINFPVFNIADISINIGFIFLLYNLFKNNR
>Mature_151_residues
MVNKIQTKLYFLSLSIFIVLIDQFTKYLISYEKLFVNKDFLLFKLDLVKNYGAAFNIFSGSRIFLSLISIIFSILIIYLI
FRKNTLNIFDLYAYSFILGGTFGNGIDRIYKGFVVDFINLNIINFPVFNIADISINIGFIFLLYNLFKNNR

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=156, Percent_Identity=32.0512820512821, Blast_Score=74, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17643; Mature: 17643

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKIQTKLYFLSLSIFIVLIDQFTKYLISYEKLFVNKDFLLFKLDLVKNYGAAFNIFSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHCCCCEEEECCC
SRIFLSLISIIFSILIIYLIFRKNTLNIFDLYAYSFILGGTFGNGIDRIYKGFVVDFINL
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
NIINFPVFNIADISINIGFIFLLYNLFKNNR
EEEECCCEEEEEEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVNKIQTKLYFLSLSIFIVLIDQFTKYLISYEKLFVNKDFLLFKLDLVKNYGAAFNIFSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHCCCCEEEECCC
SRIFLSLISIIFSILIIYLIFRKNTLNIFDLYAYSFILGGTFGNGIDRIYKGFVVDFINL
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
NIINFPVFNIADISINIGFIFLLYNLFKNNR
EEEECCCEEEEEEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12917641 [H]