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The map label for this gene is ubiE [H]

Identifier: 123968472

GI number: 123968472

Start: 807302

End: 808357

Strand: Reverse

Name: ubiE [H]

Synonym: A9601_09391

Alternate gene names: 123968472

Gene position: 808357-807302 (Counterclockwise)

Preceding gene: 123968473

Following gene: 123968471

Centisome position: 48.41

GC content: 30.02

Gene sequence:

>1056_bases
ATGGCTAGGGAATCTATCTCAAAAATTGCATATAAAACGCTACAACAAAGTAAAAGCATTGCAGGTTTCGCTCACAAGCA
GATTAGTTCAAGATTAATGAACTTTATTCTTCCCGATTCAAAGCTTGAAAATTTTAATATAGATAGAGACCTTCTAATGC
AAATCCAAAATTCAATGGATATCTTAAGAGAAGAAGATTGGAATGATGCAGAAAAAAATATATATCCAAAAAAATTATTG
TTTGACGAACCATGGCTTAGATATCTAACTCAATATCCTAAAATTTGGCTTGATATGCCTAACACATGGGATAGACGCAG
AAAACAAAACTTTGATGATCTTCCAAAATCAATTGATAAAGATAATTATCCTCAATATTATTTGAGAAATTTTCATCATC
AAACAGATGGTTATTTATCAGATTTTTCAGCCAGCATTTATGACCTACAAGTTGAGATACTTTTCAATGGGAGTGCTGAC
TCAATGAGGAGAAGAATAATTAAACCAATAAAAGAAGGACTTGAAATTTTTAGAGATAGAAAAAAAAGTTCTATAAAATT
ACTTGATGTGGCTACAGGATCAGGAAGAACATTAAAACAATTAAGAGCAGCATTTCCTAAAGAAAAAATTACAGGCATTG
ATTTATCTGATTCATACTTAAAAGAGGCAAGTAGATATATTTCAGATTTAGATGGAGATTTAATTCAGTTGATAAAAGGC
AACGCTGAGGAATTACCTTTTGAAAATGATAGTTTTCAATGCATTTCTTGTGTTTACCTGTTTCACGAATTACCTAGAAC
AATTAGAGCTAAAGTATTAAATGAATTTTTTAGAGTTCTTGAACCTGGTGGAATATTAGTTTTAGCTGATTCAATTCAAA
TAAGTGATTCACCTGACTTTACATCTGTAATGGAAAGCTTCTATAAATCATTTCATGAGCCTTTTTATTGTGATTACATA
AAAGAGGATATAAATTCTAAAATTGAGGATGTAGGGTTTAAAGATGTAAAATCAAATTCCTTTTTTATGACCAAAGTATG
GTCTGCTGTAAAGTAA

Upstream 100 bases:

>100_bases
TAAAAAAAACAATAGTTTAAATTAATCAATTTGAGAAATATCACAAAATATTCTCAAATTGATTTTTTTTTTGTTGGAAT
ATATATATATAAATCGAAAA

Downstream 100 bases:

>100_bases
AAAAAAACTCCTATGACCTATTGGGATAAAGATACTATTAAGCTGGTTCAAAGTCTTAATGACAAATTAAAGATTGATCA
TTCTAAATGGCATAAAGATA

Product: methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MARESISKIAYKTLQQSKSIAGFAHKQISSRLMNFILPDSKLENFNIDRDLLMQIQNSMDILREEDWNDAEKNIYPKKLL
FDEPWLRYLTQYPKIWLDMPNTWDRRRKQNFDDLPKSIDKDNYPQYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSAD
SMRRRIIKPIKEGLEIFRDRKKSSIKLLDVATGSGRTLKQLRAAFPKEKITGIDLSDSYLKEASRYISDLDGDLIQLIKG
NAEELPFENDSFQCISCVYLFHELPRTIRAKVLNEFFRVLEPGGILVLADSIQISDSPDFTSVMESFYKSFHEPFYCDYI
KEDINSKIEDVGFKDVKSNSFFMTKVWSAVK

Sequences:

>Translated_351_residues
MARESISKIAYKTLQQSKSIAGFAHKQISSRLMNFILPDSKLENFNIDRDLLMQIQNSMDILREEDWNDAEKNIYPKKLL
FDEPWLRYLTQYPKIWLDMPNTWDRRRKQNFDDLPKSIDKDNYPQYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSAD
SMRRRIIKPIKEGLEIFRDRKKSSIKLLDVATGSGRTLKQLRAAFPKEKITGIDLSDSYLKEASRYISDLDGDLIQLIKG
NAEELPFENDSFQCISCVYLFHELPRTIRAKVLNEFFRVLEPGGILVLADSIQISDSPDFTSVMESFYKSFHEPFYCDYI
KEDINSKIEDVGFKDVKSNSFFMTKVWSAVK
>Mature_350_residues
ARESISKIAYKTLQQSKSIAGFAHKQISSRLMNFILPDSKLENFNIDRDLLMQIQNSMDILREEDWNDAEKNIYPKKLLF
DEPWLRYLTQYPKIWLDMPNTWDRRRKQNFDDLPKSIDKDNYPQYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSADS
MRRRIIKPIKEGLEIFRDRKKSSIKLLDVATGSGRTLKQLRAAFPKEKITGIDLSDSYLKEASRYISDLDGDLIQLIKGN
AEELPFENDSFQCISCVYLFHELPRTIRAKVLNEFFRVLEPGGILVLADSIQISDSPDFTSVMESFYKSFHEPFYCDYIK
EDINSKIEDVGFKDVKSNSFFMTKVWSAVK

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014122
- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 41103; Mature: 40972

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARESISKIAYKTLQQSKSIAGFAHKQISSRLMNFILPDSKLENFNIDRDLLMQIQNSMD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
ILREEDWNDAEKNIYPKKLLFDEPWLRYLTQYPKIWLDMPNTWDRRRKQNFDDLPKSIDK
HHHCCCCCCHHHCCCCHHHHCCCHHHHHHHHCCEEEECCCCHHHHHHHCCHHHHHHHCCC
DNYPQYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSADSMRRRIIKPIKEGLEIFRDR
CCCCHHHHHHHCCCCCCHHHHHCCHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
KKSSIKLLDVATGSGRTLKQLRAAFPKEKITGIDLSDSYLKEASRYISDLDGDLIQLIKG
CCCCEEEEEECCCCCHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC
NAEELPFENDSFQCISCVYLFHELPRTIRAKVLNEFFRVLEPGGILVLADSIQISDSPDF
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEECCCCCH
TSVMESFYKSFHEPFYCDYIKEDINSKIEDVGFKDVKSNSFFMTKVWSAVK
HHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
ARESISKIAYKTLQQSKSIAGFAHKQISSRLMNFILPDSKLENFNIDRDLLMQIQNSMD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
ILREEDWNDAEKNIYPKKLLFDEPWLRYLTQYPKIWLDMPNTWDRRRKQNFDDLPKSIDK
HHHCCCCCCHHHCCCCHHHHCCCHHHHHHHHCCEEEECCCCHHHHHHHCCHHHHHHHCCC
DNYPQYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSADSMRRRIIKPIKEGLEIFRDR
CCCCHHHHHHHCCCCCCHHHHHCCHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
KKSSIKLLDVATGSGRTLKQLRAAFPKEKITGIDLSDSYLKEASRYISDLDGDLIQLIKG
CCCCEEEEEECCCCCHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC
NAEELPFENDSFQCISCVYLFHELPRTIRAKVLNEFFRVLEPGGILVLADSIQISDSPDF
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEECCCCCH
TSVMESFYKSFHEPFYCDYIKEDINSKIEDVGFKDVKSNSFFMTKVWSAVK
HHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]