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The map label for this gene is tqsA [H]

Identifier: 123968466

GI number: 123968466

Start: 803297

End: 804340

Strand: Reverse

Name: tqsA [H]

Synonym: A9601_09331

Alternate gene names: 123968466

Gene position: 804340-803297 (Counterclockwise)

Preceding gene: 123968467

Following gene: 123968459

Centisome position: 48.17

GC content: 26.25

Gene sequence:

>1044_bases
TTGAATAGTTCATCATATTTCAAGTTAGTAGTAATATTAATCACTTTATTAATAGTATGGACTTTAAGGGATTTTCTCCT
ACTAATAATTTGTTCTTTAGTAATTTCAAATATTGTATGTAATTTATCTAATCAAATCCAAAAAGGTTTGAAAATTCCTC
GATCGATTTCTTTGTTTCTTGTCTTAGCCGTCATATCAGTAATAATATTTACTATTTTTATTCTTGTATTACCTCCGTTT
ATAAAAGAATTCAATGAAATACTAGTTGACATTCCAAATGCTTTATCAAAAATAAATATATTGATCAATACAAATCTGAA
CAAATTTAATAACTTATTTTATGGCAAACAATCAGAAAATGTTATAGACATATTCAGTTTAATAAATAATGTAGTTACCA
TTCCAGATGTCTCAACTATTGCAAAAGCTATTCAAGAAAGTTTTAAGAATTTAATTAATATTGCGGGGAATCTAGGTTCA
GGTCTTTTGAGATTAATATTCGTATTAGCAGTGAGTTTGATGATTTCTATTGAACCAAAACAATATAAAGAAAATGTACT
TCTATTAATACCAAAAAATTACCGTAATAAATTTAGAAATATTCTGGAAAAATGCAATATTGCATTAGCAAATTGGACCT
TTTCTATGGTCATAAGCTCATTATCAGTAGGTTTATTATCATTAATAGTTTTATCTATATTAGATGTCAAATACGTTGTC
TCAAATGCCTTAATAGCAATGGTTCTTAATATAATTCCGAATATAGGTCCAGTTATAAGTGGTATATTTCCAATCTCAAT
TGCACTACTAGATAATTTTTGGAAACCACTGGCAGTTTTAGGATCATATATAATTATTCAAAATATTGAAAGCTATATCA
TAATGCCATCTATAATGAAGAAAAAAGCAAACCTACTTCCTGGTTTGACATTAATATCACAATTTGGATTTACCTTCATT
TTTGGTCCATTAGGATTAATACTATCTCTTCCATTAGCTGTAGTAATACAGGTTTTAATCAAAGAATCATTTAAAGATAT
TTAA

Upstream 100 bases:

>100_bases
AAGAACACGCCAGACTTTGACAGATTTATGAGATTTGCAAATAGTTATGCCAAATCAAATGGATTAGGATATTCTGAAAA
GAAGTAGAATATTATGAAAA

Downstream 100 bases:

>100_bases
AAACTACTTGATTAATTTTTTATATAAATATGGGTATGAAAAAAGTATAAAGATAGCTAAGGGGTGTTTACCCATAGCAA
AATATAAAGAGTTAAAAGTA

Product: permease

Products: NA

Alternate protein names: Transport of quorum-sensing signal protein [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MNSSSYFKLVVILITLLIVWTLRDFLLLIICSLVISNIVCNLSNQIQKGLKIPRSISLFLVLAVISVIIFTIFILVLPPF
IKEFNEILVDIPNALSKINILINTNLNKFNNLFYGKQSENVIDIFSLINNVVTIPDVSTIAKAIQESFKNLINIAGNLGS
GLLRLIFVLAVSLMISIEPKQYKENVLLLIPKNYRNKFRNILEKCNIALANWTFSMVISSLSVGLLSLIVLSILDVKYVV
SNALIAMVLNIIPNIGPVISGIFPISIALLDNFWKPLAVLGSYIIIQNIESYIIMPSIMKKKANLLPGLTLISQFGFTFI
FGPLGLILSLPLAVVIQVLIKESFKDI

Sequences:

>Translated_347_residues
MNSSSYFKLVVILITLLIVWTLRDFLLLIICSLVISNIVCNLSNQIQKGLKIPRSISLFLVLAVISVIIFTIFILVLPPF
IKEFNEILVDIPNALSKINILINTNLNKFNNLFYGKQSENVIDIFSLINNVVTIPDVSTIAKAIQESFKNLINIAGNLGS
GLLRLIFVLAVSLMISIEPKQYKENVLLLIPKNYRNKFRNILEKCNIALANWTFSMVISSLSVGLLSLIVLSILDVKYVV
SNALIAMVLNIIPNIGPVISGIFPISIALLDNFWKPLAVLGSYIIIQNIESYIIMPSIMKKKANLLPGLTLISQFGFTFI
FGPLGLILSLPLAVVIQVLIKESFKDI
>Mature_347_residues
MNSSSYFKLVVILITLLIVWTLRDFLLLIICSLVISNIVCNLSNQIQKGLKIPRSISLFLVLAVISVIIFTIFILVLPPF
IKEFNEILVDIPNALSKINILINTNLNKFNNLFYGKQSENVIDIFSLINNVVTIPDVSTIAKAIQESFKNLINIAGNLGS
GLLRLIFVLAVSLMISIEPKQYKENVLLLIPKNYRNKFRNILEKCNIALANWTFSMVISSLSVGLLSLIVLSILDVKYVV
SNALIAMVLNIIPNIGPVISGIFPISIALLDNFWKPLAVLGSYIIIQNIESYIIMPSIMKKKANLLPGLTLISQFGFTFI
FGPLGLILSLPLAVVIQVLIKESFKDI

Specific function: Controls the transport of the quorum-sensing signal AI-2 either by enhancing its secretion or inhibiting its uptake and consequently represses biofilm formation and motility and affects the global gene expression in biofilms [H]

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family [H]

Homologues:

Organism=Escherichia coli, GI1787885, Length=125, Percent_Identity=32.8, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002549 [H]

Pfam domain/function: PF01594 UPF0118 [H]

EC number: NA

Molecular weight: Translated: 38573; Mature: 38573

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSSYFKLVVILITLLIVWTLRDFLLLIICSLVISNIVCNLSNQIQKGLKIPRSISLFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VLAVISVIIFTIFILVLPPFIKEFNEILVDIPNALSKINILINTNLNKFNNLFYGKQSEN
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHCCCCCCCCC
VIDIFSLINNVVTIPDVSTIAKAIQESFKNLINIAGNLGSGLLRLIFVLAVSLMISIEPK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCH
QYKENVLLLIPKNYRNKFRNILEKCNIALANWTFSMVISSLSVGLLSLIVLSILDVKYVV
HHHCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNALIAMVLNIIPNIGPVISGIFPISIALLDNFWKPLAVLGSYIIIQNIESYIIMPSIMK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKANLLPGLTLISQFGFTFIFGPLGLILSLPLAVVIQVLIKESFKDI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSSSYFKLVVILITLLIVWTLRDFLLLIICSLVISNIVCNLSNQIQKGLKIPRSISLFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VLAVISVIIFTIFILVLPPFIKEFNEILVDIPNALSKINILINTNLNKFNNLFYGKQSEN
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHCCCCCCCCC
VIDIFSLINNVVTIPDVSTIAKAIQESFKNLINIAGNLGSGLLRLIFVLAVSLMISIEPK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCH
QYKENVLLLIPKNYRNKFRNILEKCNIALANWTFSMVISSLSVGLLSLIVLSILDVKYVV
HHHCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNALIAMVLNIIPNIGPVISGIFPISIALLDNFWKPLAVLGSYIIIQNIESYIIMPSIMK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKANLLPGLTLISQFGFTFIFGPLGLILSLPLAVVIQVLIKESFKDI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]