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The map label for this gene is 123968378

Identifier: 123968378

GI number: 123968378

Start: 731760

End: 732827

Strand: Reverse

Name: 123968378

Synonym: A9601_08451

Alternate gene names: NA

Gene position: 732827-731760 (Counterclockwise)

Preceding gene: 123968379

Following gene: 123968377

Centisome position: 43.88

GC content: 38.01

Gene sequence:

>1068_bases
ATGGCTTTAAATTATTACAAAAATGAGCTTAAAGAAAATGCTCAATTACTAGCTTCTAAAGGAAAAGGAATATTAGCGGT
AGATGAATCCACTAAAACAGTAGGTAAAAGACTCGCTGGAATTGGCGTTGAGAATACTGAAGACAATAGGAAGGCATATA
GAGGAATGCTTTTTACTACACAAGGTCTTGGCAAATATATAAGTGGAGCAATCCTCTTCGAAGAAACTCTTTATCAGAAT
CACCAAGATGGCGAGTCAATGGTTAAGAAACTAAATGATTTAGGTATTATTCCAGGTATAAAGGTCGATAAAGGCCTAAA
TCCACTTCCAGGAGGAGGAGATGTAGAAACTTTTTGCTCTGGCCTAGATGGGTTAGTTGAAAGAGCCGCAAAATATTATG
AACAAGGTGCCAGATTTGCAAAGTGGAGAGCAGTTCTGCAAATTACAAATGATGGTTGTCCTTCAAAACTATCAATTCAA
GAGAATGCTTGGGGATTAGCAAGGTATGCAAGATCAGTTCAAGAATCTGGGTTAGTACCAATTATTGAACCAGAAATCTT
AATGGACGGCGACCATACTATTGAAAAAACTGCTGAAGTTCAAGAAGAGGTAATAAAGCAGGTTTATATTGCCTGTCAAG
CAAATGGAGTATTTCTAGAAGGTACTCTATTAAAACCTTCTATGACTGTTAATGGAGCAGATTGTCCAACAAAGGCTGAT
CCTATGAAGGTTGCTGAAATGACAATTAGAACTATGGAAAGATGCGTTCCTGCATCTGTTCCTGGAATAGTTTTCTTATC
AGGAGGGTTAAGCGAAGAAGCTGCTTCAGTTTATCTAAATAATATGAACACTCTTTACAGGAAAGCTTTATGGAATGTTT
CATTCTCCTATGGAAGAGCATTACAACATTCATGCTTAAAGGCCTGGAAAGGAAGCGATGTTGAAGGAGGTCAAAAAGCA
TTAATAGCAAGAGCTCAAGCAAACTCTGAAGCTTCAAAAGGTGCCTATGTAGCAGGATCTCAACCTTCATCTGATGAGCA
ATTGTTTGTGGCCGGCTACACTTATTAA

Upstream 100 bases:

>100_bases
TATACATTTATAAGTAGCAATTATCACCCCATAAAGTATTGAATTGATTTTATTTTTTTTTCATATTCTGGAAAAATCAA
TTGAACTGAATTATTAAAGA

Downstream 100 bases:

>100_bases
CTAAAAACTCCTAAAAATGTACTCTGGGTCATAAAATAAGTTTCTTTAATTTAGTATTTTGTATATCTAATGACGTGACA
TTTGATACCTCTTTATACTA

Product: fructose-1,6-bisphosphate aldolase class I

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MALNYYKNELKENAQLLASKGKGILAVDESTKTVGKRLAGIGVENTEDNRKAYRGMLFTTQGLGKYISGAILFEETLYQN
HQDGESMVKKLNDLGIIPGIKVDKGLNPLPGGGDVETFCSGLDGLVERAAKYYEQGARFAKWRAVLQITNDGCPSKLSIQ
ENAWGLARYARSVQESGLVPIIEPEILMDGDHTIEKTAEVQEEVIKQVYIACQANGVFLEGTLLKPSMTVNGADCPTKAD
PMKVAEMTIRTMERCVPASVPGIVFLSGGLSEEAASVYLNNMNTLYRKALWNVSFSYGRALQHSCLKAWKGSDVEGGQKA
LIARAQANSEASKGAYVAGSQPSSDEQLFVAGYTY

Sequences:

>Translated_355_residues
MALNYYKNELKENAQLLASKGKGILAVDESTKTVGKRLAGIGVENTEDNRKAYRGMLFTTQGLGKYISGAILFEETLYQN
HQDGESMVKKLNDLGIIPGIKVDKGLNPLPGGGDVETFCSGLDGLVERAAKYYEQGARFAKWRAVLQITNDGCPSKLSIQ
ENAWGLARYARSVQESGLVPIIEPEILMDGDHTIEKTAEVQEEVIKQVYIACQANGVFLEGTLLKPSMTVNGADCPTKAD
PMKVAEMTIRTMERCVPASVPGIVFLSGGLSEEAASVYLNNMNTLYRKALWNVSFSYGRALQHSCLKAWKGSDVEGGQKA
LIARAQANSEASKGAYVAGSQPSSDEQLFVAGYTY
>Mature_354_residues
ALNYYKNELKENAQLLASKGKGILAVDESTKTVGKRLAGIGVENTEDNRKAYRGMLFTTQGLGKYISGAILFEETLYQNH
QDGESMVKKLNDLGIIPGIKVDKGLNPLPGGGDVETFCSGLDGLVERAAKYYEQGARFAKWRAVLQITNDGCPSKLSIQE
NAWGLARYARSVQESGLVPIIEPEILMDGDHTIEKTAEVQEEVIKQVYIACQANGVFLEGTLLKPSMTVNGADCPTKADP
MKVAEMTIRTMERCVPASVPGIVFLSGGLSEEAASVYLNNMNTLYRKALWNVSFSYGRALQHSCLKAWKGSDVEGGQKAL
IARAQANSEASKGAYVAGSQPSSDEQLFVAGYTY

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI40354205, Length=354, Percent_Identity=50.5649717514124, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI4885063, Length=354, Percent_Identity=47.7401129943503, Blast_Score=308, Evalue=4e-84,
Organism=Homo sapiens, GI34577112, Length=354, Percent_Identity=47.4576271186441, Blast_Score=300, Evalue=1e-81,
Organism=Homo sapiens, GI34577110, Length=354, Percent_Identity=47.4576271186441, Blast_Score=300, Evalue=1e-81,
Organism=Homo sapiens, GI4557305, Length=354, Percent_Identity=47.4576271186441, Blast_Score=300, Evalue=1e-81,
Organism=Homo sapiens, GI193794814, Length=354, Percent_Identity=47.4576271186441, Blast_Score=300, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI25150450, Length=358, Percent_Identity=47.2067039106145, Blast_Score=305, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI71983985, Length=352, Percent_Identity=47.7272727272727, Blast_Score=298, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI71983990, Length=233, Percent_Identity=49.7854077253219, Blast_Score=211, Evalue=6e-55,
Organism=Drosophila melanogaster, GI45553577, Length=354, Percent_Identity=50.5649717514124, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI24650282, Length=352, Percent_Identity=50.2840909090909, Blast_Score=311, Evalue=3e-85,
Organism=Drosophila melanogaster, GI24650280, Length=352, Percent_Identity=50.2840909090909, Blast_Score=311, Evalue=3e-85,
Organism=Drosophila melanogaster, GI24650278, Length=352, Percent_Identity=50.2840909090909, Blast_Score=311, Evalue=3e-85,
Organism=Drosophila melanogaster, GI221459619, Length=337, Percent_Identity=51.0385756676558, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24650288, Length=337, Percent_Identity=51.0385756676558, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24650304, Length=348, Percent_Identity=45.1149425287356, Blast_Score=273, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38500; Mature: 38369

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00158 ALDOLASE_CLASS_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNYYKNELKENAQLLASKGKGILAVDESTKTVGKRLAGIGVENTEDNRKAYRGMLFTT
CCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHEEEH
QGLGKYISGAILFEETLYQNHQDGESMVKKLNDLGIIPGIKVDKGLNPLPGGGDVETFCS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCHHHHHH
GLDGLVERAAKYYEQGARFAKWRAVLQITNDGCPSKLSIQENAWGLARYARSVQESGLVP
HHHHHHHHHHHHHHHCCHHHHHHEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCE
IIEPEILMDGDHTIEKTAEVQEEVIKQVYIACQANGVFLEGTLLKPSMTVNGADCPTKAD
EECCCEEECCCCHHHHHHHHHHHHHHHHHHHEECCCEEEEEEEECCCEEECCCCCCCCCC
PMKVAEMTIRTMERCVPASVPGIVFLSGGLSEEAASVYLNNMNTLYRKALWNVSFSYGRA
CHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LQHSCLKAWKGSDVEGGQKALIARAQANSEASKGAYVAGSQPSSDEQLFVAGYTY
HHHHHHHHHCCCCCCCCHHHHEEHHHCCCCCCCCEEEECCCCCCCCEEEEEEECC
>Mature Secondary Structure 
ALNYYKNELKENAQLLASKGKGILAVDESTKTVGKRLAGIGVENTEDNRKAYRGMLFTT
CCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHEEEH
QGLGKYISGAILFEETLYQNHQDGESMVKKLNDLGIIPGIKVDKGLNPLPGGGDVETFCS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCHHHHHH
GLDGLVERAAKYYEQGARFAKWRAVLQITNDGCPSKLSIQENAWGLARYARSVQESGLVP
HHHHHHHHHHHHHHHCCHHHHHHEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCE
IIEPEILMDGDHTIEKTAEVQEEVIKQVYIACQANGVFLEGTLLKPSMTVNGADCPTKAD
EECCCEEECCCCHHHHHHHHHHHHHHHHHHHEECCCEEEEEEEECCCEEECCCCCCCCCC
PMKVAEMTIRTMERCVPASVPGIVFLSGGLSEEAASVYLNNMNTLYRKALWNVSFSYGRA
CHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LQHSCLKAWKGSDVEGGQKALIARAQANSEASKGAYVAGSQPSSDEQLFVAGYTY
HHHHHHHHHCCCCCCCCHHHHEEHHHCCCCCCCCEEEECCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]