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The map label for this gene is purQ [H]

Identifier: 123968376

GI number: 123968376

Start: 729823

End: 730488

Strand: Direct

Name: purQ [H]

Synonym: A9601_08431

Alternate gene names: 123968376

Gene position: 729823-730488 (Clockwise)

Preceding gene: 123968375

Following gene: 123968394

Centisome position: 43.7

GC content: 36.19

Gene sequence:

>666_bases
ATGGATAATTTTACTGTAGGAGTTGTTGTCTTCCCTGGTTCTAATTGTGATCGTGATGTTTCATGGGCATTGGAAGGTTG
TTTAGACATAAGAACAAAATACTTGTGGCATGAGTCTTCAGATTTAAGTGATGTAGATGCAATAGTTTTACCCGGAGGAT
TTAGCTATGGTGATTATTTAAGATGCGGAGCAATTGCGAGATTCTCTCCATTAATAAATGCCTTGGATGAGTTTGTTAAA
AGCGGGAAAAGAGTTTTAGGAATTTGTAATGGGTTTCAAATTTTGACAGAATCAGGGTTTTTGCCTGGTGCGCTTGTTGC
AAATAAAAATCTTAATTTTATCTGTGATGACGTTGAACTGGACATCATTTCTTCAAAAGGAGGTTGGTTCAATAATGTAG
ATGAAAAACAAACAATTAAGTTGCCAATAGCGCATGGGGAAGGAAGATATCATTGTGATTCTGATACTTTAAAGAAACTT
GTAGATAATGAATTGATCGCTTTGAGATATAGAAATAATCCCAATGGATCCTCATTCGATATCGCGGGCATAACTAATGA
GAAGGGAAATGTTCTTGGTTTAATGCCTCATCCAGAGCGAGCATGCGACGAGACAATTGGTGGGACTGATGGTCTCTTTA
CATTAAAATCATTAATATTGAAATAA

Upstream 100 bases:

>100_bases
GGTGAAGACGAAGTAAGGAAAAAAATTGATTTATTGTGTGATAGGTTATTCGCAAATATTGTTATTGAAGATTATGAGTA
TTCACTAGAAAAATTATAAG

Downstream 100 bases:

>100_bases
AAAAAGACCTCCAATTTTGGTGGTCTTTTTTTATTTAATTTGGGAAGAAATTAAACAGTAGCTTTTACTTTTGGATCCAA
ATCACCTTTTGCGTAAAGAT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYLRCGAIARFSPLINALDEFVK
SGKRVLGICNGFQILTESGFLPGALVANKNLNFICDDVELDIISSKGGWFNNVDEKQTIKLPIAHGEGRYHCDSDTLKKL
VDNELIALRYRNNPNGSSFDIAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK

Sequences:

>Translated_221_residues
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYLRCGAIARFSPLINALDEFVK
SGKRVLGICNGFQILTESGFLPGALVANKNLNFICDDVELDIISSKGGWFNNVDEKQTIKLPIAHGEGRYHCDSDTLKKL
VDNELIALRYRNNPNGSSFDIAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK
>Mature_221_residues
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYLRCGAIARFSPLINALDEFVK
SGKRVLGICNGFQILTESGFLPGALVANKNLNFICDDVELDIISSKGGWFNNVDEKQTIKLPIAHGEGRYHCDSDTLKKL
VDNELIALRYRNNPNGSSFDIAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=197, Percent_Identity=32.48730964467, Blast_Score=77, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6321498, Length=237, Percent_Identity=26.5822784810127, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24582111, Length=232, Percent_Identity=29.7413793103448, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24582109, Length=232, Percent_Identity=29.7413793103448, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17137292, Length=232, Percent_Identity=29.7413793103448, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24178; Mature: 24178

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYL
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCEEEECCCCCCCCHH
RCGAIARFSPLINALDEFVKSGKRVLGICNGFQILTESGFLPGALVANKNLNFICDDVEL
HHCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCCCCEEEECCCCCEEECCEEE
DIISSKGGWFNNVDEKQTIKLPIAHGEGRYHCDSDTLKKLVDNELIALRYRNNPNGSSFD
EEEECCCCCCCCCCCCEEEEEEEECCCCCEEECHHHHHHHHCCCEEEEEECCCCCCCEEE
IAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK
EEEEECCCCCEEEECCCCHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYL
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCEEEECCCCCCCCHH
RCGAIARFSPLINALDEFVKSGKRVLGICNGFQILTESGFLPGALVANKNLNFICDDVEL
HHCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCCCCEEEECCCCCEEECCEEE
DIISSKGGWFNNVDEKQTIKLPIAHGEGRYHCDSDTLKKLVDNELIALRYRNNPNGSSFD
EEEECCCCCCCCCCCCEEEEEEEECCCCCEEECHHHHHHHHCCCEEEEEECCCCCCCEEE
IAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK
EEEEECCCCCEEEECCCCHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA