Click here to switch to the map view.

The map label for this gene is cobK [H]

Identifier: 123968095

GI number: 123968095

Start: 487312

End: 488109

Strand: Direct

Name: cobK [H]

Synonym: A9601_05601

Alternate gene names: 123968095

Gene position: 487312-488109 (Clockwise)

Preceding gene: 123968093

Following gene: 123968096

Centisome position: 29.18

GC content: 27.82

Gene sequence:

>798_bases
ATGCAGAATCCAGGAAATTGCTATAAAAATGTTTGGATCCTATCAGGAACTTCGGATGGACCTGTAATAGCTAATAGGCT
TCTTGAACTTAATTATTCAGTCTTTGCAAGTGTTTTATCTTATAAAGCAGGGCAAGCTTATATCGAAAATCCAAAGTTAC
ATATCATTACGGGGAAATTAAATAATAAAGATCAAATAATTAATTTCATAAATAAAAATAAAATCACATGCGTTGTCGAC
GCTACTCATCCTTTTGCCATAATAATTTCTAAAAATCTTAATAATGCATGTAAAGAAATTAATACACCTCTTTTACTATT
TGAGAGGAAATCTCTAATAAATAACACTAATAATTTTTTTTATATTGATCATTTAAAGGATATAAATAATGTTGATATAG
CAAATAAGAATATTCTTCTTGCAATAGGATCAAGATTCCTTAACGAGACAGCTAGTTATTATATGAATTGTAAAGCAAAT
GTATTTACAAGGGTTCTTCCAACTTATGAGAGTATAACTAAAGCTTTTGGATCATGTATTAAAAATTCCAACATAGCGAT
ACTTGAACCGAGTAAAAATAATAATAGCATTTTAGAAAAAAGACTTTGTGATTTTTGGGAGATAGATTATGTTCTATGCA
GAGAATCTGGAAGTTATTCTCAGAAAAACTGGGAGAGTATAGTTTCTGGAAGTAAGATGAAGTTATTTTTGGTTAAAAGG
CCGAAAGTTAAAAATGATTATTCTTACTCTTTTGATCAATATCACAATTTGATAAATCACATAATTAAAAAATATTGA

Upstream 100 bases:

>100_bases
AGTTTGGTTTTCTTTGGTATACCTCATTTGGGGAGCGCTATTAATGACCGCCTGAATTAAACAATGATTCATTACTTACT
ATTTAATTAAAGACATACTG

Downstream 100 bases:

>100_bases
TGTTTAATTCATTATGGAAGTATTAGTTATGATCACAACTGAATCAAGTAACGCAAATGCTTTGCGAATGGCTAAATTAC
TAATACAAAATAAACTTGCA

Product: precorrin-6X reductase

Products: Precorrin 6A; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MQNPGNCYKNVWILSGTSDGPVIANRLLELNYSVFASVLSYKAGQAYIENPKLHIITGKLNNKDQIINFINKNKITCVVD
ATHPFAIIISKNLNNACKEINTPLLLFERKSLINNTNNFFYIDHLKDINNVDIANKNILLAIGSRFLNETASYYMNCKAN
VFTRVLPTYESITKAFGSCIKNSNIAILEPSKNNNSILEKRLCDFWEIDYVLCRESGSYSQKNWESIVSGSKMKLFLVKR
PKVKNDYSYSFDQYHNLINHIIKKY

Sequences:

>Translated_265_residues
MQNPGNCYKNVWILSGTSDGPVIANRLLELNYSVFASVLSYKAGQAYIENPKLHIITGKLNNKDQIINFINKNKITCVVD
ATHPFAIIISKNLNNACKEINTPLLLFERKSLINNTNNFFYIDHLKDINNVDIANKNILLAIGSRFLNETASYYMNCKAN
VFTRVLPTYESITKAFGSCIKNSNIAILEPSKNNNSILEKRLCDFWEIDYVLCRESGSYSQKNWESIVSGSKMKLFLVKR
PKVKNDYSYSFDQYHNLINHIIKKY
>Mature_265_residues
MQNPGNCYKNVWILSGTSDGPVIANRLLELNYSVFASVLSYKAGQAYIENPKLHIITGKLNNKDQIINFINKNKITCVVD
ATHPFAIIISKNLNNACKEINTPLLLFERKSLINNTNNFFYIDHLKDINNVDIANKNILLAIGSRFLNETASYYMNCKAN
VFTRVLPTYESITKAFGSCIKNSNIAILEPSKNNNSILEKRLCDFWEIDYVLCRESGSYSQKNWESIVSGSKMKLFLVKR
PKVKNDYSYSFDQYHNLINHIIKKY

Specific function: Catalyzes the reduction of the macrocycle of cobalt- precorrin-6X into cobalt-precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: 1.3.1.54

Molecular weight: Translated: 30359; Mature: 30359

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNPGNCYKNVWILSGTSDGPVIANRLLELNYSVFASVLSYKAGQAYIENPKLHIITGKL
CCCCCCCEEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCCCEEECCCEEEEEECCC
NNKDQIINFINKNKITCVVDATHPFAIIISKNLNNACKEINTPLLLFERKSLINNTNNFF
CCHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCHHHHHCCCCEEEEECHHHHCCCCCEE
YIDHLKDINNVDIANKNILLAIGSRFLNETASYYMNCKANVFTRVLPTYESITKAFGSCI
EEEECCCCCCCEECCCCEEEEEHHHHHHHHHHHEECCCHHHHHHHHCCHHHHHHHHHHHH
KNSNIAILEPSKNNNSILEKRLCDFWEIDYVLCRESGSYSQKNWESIVSGSKMKLFLVKR
CCCCEEEECCCCCCCHHHHHHHCHHHCCCEEEEECCCCCCHHHHHHHHCCCCEEEEEEEC
PKVKNDYSYSFDQYHNLINHIIKKY
CCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQNPGNCYKNVWILSGTSDGPVIANRLLELNYSVFASVLSYKAGQAYIENPKLHIITGKL
CCCCCCCEEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCCCEEECCCEEEEEECCC
NNKDQIINFINKNKITCVVDATHPFAIIISKNLNNACKEINTPLLLFERKSLINNTNNFF
CCHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCHHHHHCCCCEEEEECHHHHCCCCCEE
YIDHLKDINNVDIANKNILLAIGSRFLNETASYYMNCKANVFTRVLPTYESITKAFGSCI
EEEECCCCCCCEECCCCEEEEEHHHHHHHHHHHEECCCHHHHHHHHCCHHHHHHHHHHHH
KNSNIAILEPSKNNNSILEKRLCDFWEIDYVLCRESGSYSQKNWESIVSGSKMKLFLVKR
CCCCEEEECCCCCCCHHHHHHHCHHHCCCEEEEECCCCCCHHHHHHHHCCCCEEEEEEEC
PKVKNDYSYSFDQYHNLINHIIKKY
CCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 6B; NADP+

Specific reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]