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The map label for this gene is map [C]

Identifier: 123968069

GI number: 123968069

Start: 462692

End: 463531

Strand: Direct

Name: map [C]

Synonym: A9601_05321

Alternate gene names: 123968069

Gene position: 462692-463531 (Clockwise)

Preceding gene: 123968064

Following gene: 123968071

Centisome position: 27.71

GC content: 35.6

Gene sequence:

>840_bases
ATGAGACATTTTGCAGATCTTTTGTTAAATAAAAATAATTCCAAAGCTAATGATCAAGTTCCTTTTATTCAGAGGAGAAG
AGGAATCGAGATAAAGTCTTCACGGGAAATAAATTTGATGAAAAAATCTAGCAGAATTGTAGCTACCGTTTTGAGAGAAA
TTAATGACTTAATTAAACCTGGAATGAGTACAAAAGATTTAGATGATTTCGCGGAAAAGAGGATAAAAAGTTTTGGAGCT
GTGCCAAGTTTCAAGGGCTACCATGGATTCCCTTCTAGTATTTGTTCTAGTATTAATAATGAGGTTGTCCACGGTATTCC
AAGTAAAAATAAAATAATTAAAAATGGTGACTTGGTTAAAATTGATACAGGGGCATATTTAGATGGTTTCCATGGAGATA
GTTGTATATCAATTTGTGTAGGAGAAGTTAGTCCAAAGGCTCAAAAACTTAGTGATGTAGCTTTTAAAGCATTGTATGCG
GGCCTTTCGAAAATCAAAGCCGGGAATACACTTCTTGATGTGGCTGGGGAAATCGAAGACGTTGTCGTAAAAAATGGCTT
TAGTGTTGTAGAAGACTACACAGGTCATGGAGTTGGACGAAATCTTCATGAAGAACCATCGGTATTTAATTTTCGGACCA
AAGAATTGCCTAACGTCGTCCTTCGCGAAGGAATGACATTAGCGGTGGAACCTATTGTTAATGAAGGGACTAAATTTTGC
AAAACACTAAATGATAGATGGACCGTAATAACAAAAGATGGAAAACTATCTGCCCAATGGGAGCATACAATAGTTGTTTT
AAAAGATGGTATTGAAATATTGACAGATCGAGATTTCTAG

Upstream 100 bases:

>100_bases
TTCATTTTCGTTTCTTTCCTATTGTTATTGATAGATTTAAGGTAGCCAAGATCATAAAGGCTATTTTGAAGATATTTACT
TATTACTATTATTTATTCCA

Downstream 100 bases:

>100_bases
GCACTAAGATTTATATTTATAGATAATTTGGCAATATAAATAATTAAAAAATTCTTTCAATGGGAAAAGTACATATGTTA
AAGGGTTTGGACTAATTATT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRHFADLLLNKNNSKANDQVPFIQRRRGIEIKSSREINLMKKSSRIVATVLREINDLIKPGMSTKDLDDFAEKRIKSFGA
VPSFKGYHGFPSSICSSINNEVVHGIPSKNKIIKNGDLVKIDTGAYLDGFHGDSCISICVGEVSPKAQKLSDVAFKALYA
GLSKIKAGNTLLDVAGEIEDVVVKNGFSVVEDYTGHGVGRNLHEEPSVFNFRTKELPNVVLREGMTLAVEPIVNEGTKFC
KTLNDRWTVITKDGKLSAQWEHTIVVLKDGIEILTDRDF

Sequences:

>Translated_279_residues
MRHFADLLLNKNNSKANDQVPFIQRRRGIEIKSSREINLMKKSSRIVATVLREINDLIKPGMSTKDLDDFAEKRIKSFGA
VPSFKGYHGFPSSICSSINNEVVHGIPSKNKIIKNGDLVKIDTGAYLDGFHGDSCISICVGEVSPKAQKLSDVAFKALYA
GLSKIKAGNTLLDVAGEIEDVVVKNGFSVVEDYTGHGVGRNLHEEPSVFNFRTKELPNVVLREGMTLAVEPIVNEGTKFC
KTLNDRWTVITKDGKLSAQWEHTIVVLKDGIEILTDRDF
>Mature_279_residues
MRHFADLLLNKNNSKANDQVPFIQRRRGIEIKSSREINLMKKSSRIVATVLREINDLIKPGMSTKDLDDFAEKRIKSFGA
VPSFKGYHGFPSSICSSINNEVVHGIPSKNKIIKNGDLVKIDTGAYLDGFHGDSCISICVGEVSPKAQKLSDVAFKALYA
GLSKIKAGNTLLDVAGEIEDVVVKNGFSVVEDYTGHGVGRNLHEEPSVFNFRTKELPNVVLREGMTLAVEPIVNEGTKFC
KTLNDRWTVITKDGKLSAQWEHTIVVLKDGIEILTDRDF

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=34.2741935483871, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI164420681, Length=249, Percent_Identity=35.3413654618474, Blast_Score=162, Evalue=3e-40,
Organism=Escherichia coli, GI1786364, Length=251, Percent_Identity=45.0199203187251, Blast_Score=217, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI71996291, Length=253, Percent_Identity=34.7826086956522, Blast_Score=158, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6323273, Length=255, Percent_Identity=35.6862745098039, Blast_Score=170, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24583427, Length=246, Percent_Identity=36.1788617886179, Blast_Score=160, Evalue=8e-40,
Organism=Drosophila melanogaster, GI21355531, Length=253, Percent_Identity=35.5731225296443, Blast_Score=155, Evalue=2e-38,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 30889; Mature: 30889

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHFADLLLNKNNSKANDQVPFIQRRRGIEIKSSREINLMKKSSRIVATVLREINDLIKP
CCHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCC
GMSTKDLDDFAEKRIKSFGAVPSFKGYHGFPSSICSSINNEVVHGIPSKNKIIKNGDLVK
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHEECCCCCCCEEECCCEEE
IDTGAYLDGFHGDSCISICVGEVSPKAQKLSDVAFKALYAGLSKIKAGNTLLDVAGEIED
EECCCEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VVVKNGFSVVEDYTGHGVGRNLHEEPSVFNFRTKELPNVVLREGMTLAVEPIVNEGTKFC
HHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCHHHHHCCCEEEECCHHHHHHHHH
KTLNDRWTVITKDGKLSAQWEHTIVVLKDGIEILTDRDF
HHCCCCEEEEEECCCEEEEECEEEEEEECCCEEECCCCC
>Mature Secondary Structure
MRHFADLLLNKNNSKANDQVPFIQRRRGIEIKSSREINLMKKSSRIVATVLREINDLIKP
CCHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCC
GMSTKDLDDFAEKRIKSFGAVPSFKGYHGFPSSICSSINNEVVHGIPSKNKIIKNGDLVK
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHEECCCCCCCEEECCCEEE
IDTGAYLDGFHGDSCISICVGEVSPKAQKLSDVAFKALYAGLSKIKAGNTLLDVAGEIED
EECCCEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VVVKNGFSVVEDYTGHGVGRNLHEEPSVFNFRTKELPNVVLREGMTLAVEPIVNEGTKFC
HHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCHHHHHCCCEEEECCHHHHHHHHH
KTLNDRWTVITKDGKLSAQWEHTIVVLKDGIEILTDRDF
HHCCCCEEEEEECCCEEEEECEEEEEEECCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]