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The map label for this gene is engA [H]

Identifier: 123967979

GI number: 123967979

Start: 383474

End: 384847

Strand: Direct

Name: engA [H]

Synonym: A9601_04421

Alternate gene names: 123967979

Gene position: 383474-384847 (Clockwise)

Preceding gene: 123967978

Following gene: 123967980

Centisome position: 22.96

GC content: 33.99

Gene sequence:

>1374_bases
TTGATTCTTCCTACAATAGCAATTATCGGAAGACCGAACGTTGGGAAATCTACCTTAGTTAATCGTCTTTGCCAAAGTAA
TGATGCAATAGTATTTGATAAGCCTGGTGTTACAAGAGATAGAACTTATCAAAATGCTTCATGGGGAGGTAAGGAATTTC
AAATAGTCGATACTGGAGGTTTAGTTTTTGATGACGAAAGTGAATTTCTCCCAGAGATAAGGACACAAGTCTTCTTGGCT
CTAGAAGAGGCTTCACTTGCGTTACTGGTGGTAGATGGAAATCAAGGCGTTACTGATGGTGATTTATCAATAGCAAAATG
GTTAAGAAACTCAAGCTGCAAAACAATTGTTGCTGTTAATAAATGCGAATCGACTACTTTAGGAATATCCCTAGCTTCAG
AGTTCTGGAAATTAGGATTGGGCGAACCTAACCCTGTTTCAGCTATTCATGGTTCAGGTACTGGAGATCTTTTAGATCTC
GTTATTGGCGAACTTCCTGAAAATAATATCCAGGATGATGAAGAAAAGATAATGATGTCAATTATTGGTAGGCCTAATGT
TGGTAAATCTAGTTTGTTAAATTCAATCTGTGGAGAAAAAAGAGCAATAGTTAGTGATATTAGTGGCACGACAACTGATT
CAATAGATACGCTTATTAAAAAAGGTGATAATAATTGGAAAATTATTGATACTGCAGGGATTAGAAGAAAGAAAAATGTT
AAATATGGCACTGAATTCTTTGGTATTAATAGGGCTTTTAAATCTATAGATAGAAGTGATGTTTGTGTTTTAGTTATAGA
TGCTGTAGATGGAGTAACTGATCAAGACCAGAAGCTGGCTGGGCGCATAGAAGAACAAGGTAGAGCTTGTATAATTGTTG
TTAATAAATGGGATCTTATAGAAAAAAATAGTTCAACAATTTATCAAGTAGAAAAAGAACTAAGATCTAAACTATATTTT
TTACACTGGTCAAAAATGATTTTTATATCTGCCCTAACTGGTCAAAGGGTTGATAATATTTTTGAGCATGCTCTTAATGC
TGTAAATCAACATAGAAGAAGAGTTACAACATCTGTAGTTAATGAAGTACTAAAAGAATCAATCAGTTGGAAAAGTCCTC
CAACGAAGAGAAGCGGCAAGCAAGGTAGGCTTTATTACGGTACTCAAGTAAAGAACAAACCTCCCACTTTTACTCTTTTT
GTAAATGACCCTAAATTATTCGGAATAACTTATAGAAGATATATTGAAAAACAAATTAGAGTAAATTTAGGCTTTGAAGG
CACACCTCTAATTTTACTTTGGAGAGGAAAACAGCAAAGAGCTTTAAATAAAGAAGTCGAAAGAGAAAATATTGAGTTAA
TTCAAAAAGATTAA

Upstream 100 bases:

>100_bases
ATTTTGGCGATCCAGAAATTAAATAAGTTTTTTTGAATAAGGTAAATGATTCTATTAAAGGTATAGTTGTAATGGATACT
ATTTTCTTTGGAGAGAAGAA

Downstream 100 bases:

>100_bases
TGAATTTGCTAACCAAATTTTCTGTTGGTCAATACGTTCATGGTAATAGAAGTTGGCTAAGAATTATAGATAGTAGATTA
AAAATAATTATCGTAATGAT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MILPTIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQIVDTGGLVFDDESEFLPEIRTQVFLA
LEEASLALLVVDGNQGVTDGDLSIAKWLRNSSCKTIVAVNKCESTTLGISLASEFWKLGLGEPNPVSAIHGSGTGDLLDL
VIGELPENNIQDDEEKIMMSIIGRPNVGKSSLLNSICGEKRAIVSDISGTTTDSIDTLIKKGDNNWKIIDTAGIRRKKNV
KYGTEFFGINRAFKSIDRSDVCVLVIDAVDGVTDQDQKLAGRIEEQGRACIIVVNKWDLIEKNSSTIYQVEKELRSKLYF
LHWSKMIFISALTGQRVDNIFEHALNAVNQHRRRVTTSVVNEVLKESISWKSPPTKRSGKQGRLYYGTQVKNKPPTFTLF
VNDPKLFGITYRRYIEKQIRVNLGFEGTPLILLWRGKQQRALNKEVERENIELIQKD

Sequences:

>Translated_457_residues
MILPTIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQIVDTGGLVFDDESEFLPEIRTQVFLA
LEEASLALLVVDGNQGVTDGDLSIAKWLRNSSCKTIVAVNKCESTTLGISLASEFWKLGLGEPNPVSAIHGSGTGDLLDL
VIGELPENNIQDDEEKIMMSIIGRPNVGKSSLLNSICGEKRAIVSDISGTTTDSIDTLIKKGDNNWKIIDTAGIRRKKNV
KYGTEFFGINRAFKSIDRSDVCVLVIDAVDGVTDQDQKLAGRIEEQGRACIIVVNKWDLIEKNSSTIYQVEKELRSKLYF
LHWSKMIFISALTGQRVDNIFEHALNAVNQHRRRVTTSVVNEVLKESISWKSPPTKRSGKQGRLYYGTQVKNKPPTFTLF
VNDPKLFGITYRRYIEKQIRVNLGFEGTPLILLWRGKQQRALNKEVERENIELIQKD
>Mature_457_residues
MILPTIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQIVDTGGLVFDDESEFLPEIRTQVFLA
LEEASLALLVVDGNQGVTDGDLSIAKWLRNSSCKTIVAVNKCESTTLGISLASEFWKLGLGEPNPVSAIHGSGTGDLLDL
VIGELPENNIQDDEEKIMMSIIGRPNVGKSSLLNSICGEKRAIVSDISGTTTDSIDTLIKKGDNNWKIIDTAGIRRKKNV
KYGTEFFGINRAFKSIDRSDVCVLVIDAVDGVTDQDQKLAGRIEEQGRACIIVVNKWDLIEKNSSTIYQVEKELRSKLYF
LHWSKMIFISALTGQRVDNIFEHALNAVNQHRRRVTTSVVNEVLKESISWKSPPTKRSGKQGRLYYGTQVKNKPPTFTLF
VNDPKLFGITYRRYIEKQIRVNLGFEGTPLILLWRGKQQRALNKEVERENIELIQKD

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=474, Percent_Identity=35.6540084388186, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI2367268, Length=93, Percent_Identity=41.9354838709677, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788919, Length=218, Percent_Identity=27.5229357798165, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=123, Percent_Identity=39.0243902439024, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=147, Percent_Identity=40.1360544217687, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51104; Mature: 51104

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILPTIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQIVDTGG
CCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCC
LVFDDESEFLPEIRTQVFLALEEASLALLVVDGNQGVTDGDLSIAKWLRNSSCKTIVAVN
EEECCCHHHHHHHHHHHEEEEECCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEEE
KCESTTLGISLASEFWKLGLGEPNPVSAIHGSGTGDLLDLVIGELPENNIQDDEEKIMMS
CCCCCEEHHHHHHHHHHCCCCCCCCCCEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
IIGRPNVGKSSLLNSICGEKRAIVSDISGTTTDSIDTLIKKGDNNWKIIDTAGIRRKKNV
HHCCCCCCHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCC
KYGTEFFGINRAFKSIDRSDVCVLVIDAVDGVTDQDQKLAGRIEEQGRACIIVVNKWDLI
CCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCEE
EKNSSTIYQVEKELRSKLYFLHWSKMIFISALTGQRVDNIFEHALNAVNQHRRRVTTSVV
ECCCCHHHHHHHHHHHHEEEEEEHHEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NEVLKESISWKSPPTKRSGKQGRLYYGTQVKNKPPTFTLFVNDPKLFGITYRRYIEKQIR
HHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHHE
VNLGFEGTPLILLWRGKQQRALNKEVERENIELIQKD
EEECCCCCCEEEEECCCHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure
MILPTIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQIVDTGG
CCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCC
LVFDDESEFLPEIRTQVFLALEEASLALLVVDGNQGVTDGDLSIAKWLRNSSCKTIVAVN
EEECCCHHHHHHHHHHHEEEEECCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEEE
KCESTTLGISLASEFWKLGLGEPNPVSAIHGSGTGDLLDLVIGELPENNIQDDEEKIMMS
CCCCCEEHHHHHHHHHHCCCCCCCCCCEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
IIGRPNVGKSSLLNSICGEKRAIVSDISGTTTDSIDTLIKKGDNNWKIIDTAGIRRKKNV
HHCCCCCCHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCC
KYGTEFFGINRAFKSIDRSDVCVLVIDAVDGVTDQDQKLAGRIEEQGRACIIVVNKWDLI
CCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCEE
EKNSSTIYQVEKELRSKLYFLHWSKMIFISALTGQRVDNIFEHALNAVNQHRRRVTTSVV
ECCCCHHHHHHHHHHHHEEEEEEHHEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NEVLKESISWKSPPTKRSGKQGRLYYGTQVKNKPPTFTLFVNDPKLFGITYRRYIEKQIR
HHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHHE
VNLGFEGTPLILLWRGKQQRALNKEVERENIELIQKD
EEECCCCCCEEEEECCCHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA