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The map label for this gene is minD [H]

Identifier: 123967882

GI number: 123967882

Start: 315530

End: 316357

Strand: Reverse

Name: minD [H]

Synonym: A9601_03451

Alternate gene names: 123967882

Gene position: 316357-315530 (Counterclockwise)

Preceding gene: 123967883

Following gene: 123967881

Centisome position: 18.94

GC content: 36.11

Gene sequence:

>828_bases
ATGTTAAAAATCGTGGGGAAGAATACTCGCACAATATTAATCTGTTCTGGTAAGGGAGGGGTTGGTAAAACAACTTTAAC
TGCAAACCTAGGGATAGCACTTGCTAATAGCGGAGCAACAACTGCTGTATTAGATGCTGATTTTGGCTTAAGAAATTTAG
ATCTTCTTCTAGGATTAGAAAATCGCATCATTTATACAGCTCAAGATGTTCTAGACAAGAACTGTCGTCTCGACCAAGCA
TTGGTTAGACATAAAAAGGAGCCTAATCTTGCTCTTCTACCTGCTGGAGATCCAAGGATGTTGGATTGGATGAAGCCCGA
AGATATGAAAAAAATTAGTGAGCTACTTAGTGAGAACTTTGATTTTGTCTTAGTAGATTGTCCTGCTGGTGTAGAAGATG
GCTTTAAAAATGCTCTTGCAGCCTGTAAAGAAGCTATTGTTGTAACTAACCCAGAATTATCCGCAGTGAGGGATGCAGAT
AGAGTAATAGGAATTCTTAATACTTCAGATATTGAGCCTATTCAACTTGTAATCAATAGAGTTCGCCCTAACATGATGGC
TAGTCAAGAAATGTTATCCATCGAAGATGTTCAAGGGATCCTTTCTTTGCCTTTATTAGGTATTGTTTTAGAAGATGAAC
AGGTAATAATAAGTACAAATAGAGGAGAGCCACTGACACTTTCAGATAGTAGATCTCCTGCAAAAAAATGTTATTTGAAT
GTTTCTCAAAGACTTACAAATAAAGATATACCAATTATCGATCCCAAAAAAGAAGGCAAAAGTCTTAAAGATAAATTCAT
GAGATTAATGCAAACAAAGGTTTTTTAA

Upstream 100 bases:

>100_bases
ATCAATAATTTGCAATAAATAAATTCAAATTAGATAAATTTAAGAATTACTTAATCTTTAAAATATTTAACTTTCTGCAT
GTGGCTTTATTATTTGTAAA

Downstream 100 bases:

>100_bases
AATGATGACTCTCAGAGATCTTATAAATAAATTACTAGGCAGAGAAACGTCTAGTGCTAATACAGCAAGAGAAAGATTAC
AACTTGTACTGGCTCATGAC

Product: putative septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MLKIVGKNTRTILICSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLENRIIYTAQDVLDKNCRLDQA
LVRHKKEPNLALLPAGDPRMLDWMKPEDMKKISELLSENFDFVLVDCPAGVEDGFKNALAACKEAIVVTNPELSAVRDAD
RVIGILNTSDIEPIQLVINRVRPNMMASQEMLSIEDVQGILSLPLLGIVLEDEQVIISTNRGEPLTLSDSRSPAKKCYLN
VSQRLTNKDIPIIDPKKEGKSLKDKFMRLMQTKVF

Sequences:

>Translated_275_residues
MLKIVGKNTRTILICSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLENRIIYTAQDVLDKNCRLDQA
LVRHKKEPNLALLPAGDPRMLDWMKPEDMKKISELLSENFDFVLVDCPAGVEDGFKNALAACKEAIVVTNPELSAVRDAD
RVIGILNTSDIEPIQLVINRVRPNMMASQEMLSIEDVQGILSLPLLGIVLEDEQVIISTNRGEPLTLSDSRSPAKKCYLN
VSQRLTNKDIPIIDPKKEGKSLKDKFMRLMQTKVF
>Mature_275_residues
MLKIVGKNTRTILICSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLENRIIYTAQDVLDKNCRLDQA
LVRHKKEPNLALLPAGDPRMLDWMKPEDMKKISELLSENFDFVLVDCPAGVEDGFKNALAACKEAIVVTNPELSAVRDAD
RVIGILNTSDIEPIQLVINRVRPNMMASQEMLSIEDVQGILSLPLLGIVLEDEQVIISTNRGEPLTLSDSRSPAKKCYLN
VSQRLTNKDIPIIDPKKEGKSLKDKFMRLMQTKVF

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=254, Percent_Identity=24.0157480314961, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1787423, Length=262, Percent_Identity=40.8396946564886, Blast_Score=192, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6322188, Length=179, Percent_Identity=27.3743016759777, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24667611, Length=201, Percent_Identity=27.363184079602, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 30195; Mature: 30195

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIVGKNTRTILICSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLE
CEEEECCCCCEEEEECCCCCCCCEEEEEECCEEEECCCCEEEEEECCCCCCCEEEEEECC
NRIIYTAQDVLDKNCRLDQALVRHKKEPNLALLPAGDPRMLDWMKPEDMKKISELLSENF
CCEEEEEHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCEECCCCCHHHHHHHHHHHCCC
DFVLVDCPAGVEDGFKNALAACKEAIVVTNPELSAVRDADRVIGILNTSDIEPIQLVINR
CEEEEECCCCHHHHHHHHHHHHHCEEEEECCCHHHHHCCCCEEEEECCCCCCHHHHHHHH
VRPNMMASQEMLSIEDVQGILSLPLLGIVLEDEQVIISTNRGEPLTLSDSRSPAKKCYLN
HCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCCCEEEECCCCCCHHHHHHH
VSQRLTNKDIPIIDPKKEGKSLKDKFMRLMQTKVF
HHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKIVGKNTRTILICSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLE
CEEEECCCCCEEEEECCCCCCCCEEEEEECCEEEECCCCEEEEEECCCCCCCEEEEEECC
NRIIYTAQDVLDKNCRLDQALVRHKKEPNLALLPAGDPRMLDWMKPEDMKKISELLSENF
CCEEEEEHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCEECCCCCHHHHHHHHHHHCCC
DFVLVDCPAGVEDGFKNALAACKEAIVVTNPELSAVRDADRVIGILNTSDIEPIQLVINR
CEEEEECCCCHHHHHHHHHHHHHCEEEEECCCHHHHHCCCCEEEEECCCCCCHHHHHHHH
VRPNMMASQEMLSIEDVQGILSLPLLGIVLEDEQVIISTNRGEPLTLSDSRSPAKKCYLN
HCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCCCEEEECCCCCCHHHHHHH
VSQRLTNKDIPIIDPKKEGKSLKDKFMRLMQTKVF
HHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]